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Prevalence, risk factors and outcomes of cardiac disease in cystic fibrosis: a multinational retrospective cohort study.
Frost F, Nazareth D, Fauchier L, Wat D, Shelley J, Austin P, Walshaw MJ, Lip GYH. Frost F, et al. Among authors: walshaw mj. Eur Respir J. 2023 Oct 26;62(4):2300174. doi: 10.1183/13993003.00174-2023. Print 2023 Oct. Eur Respir J. 2023. PMID: 37474158 Free PMC article.
BACKGROUND: Although people living with cystic fibrosis (PwCF) often have some risk factors for cardiovascular disease, including diabetes and chronic inflammation, little is known about the long-term cardiac risk in this condition. We aimed to determine the characteristic …
BACKGROUND: Although people living with cystic fibrosis (PwCF) often have some risk factors for cardiovascular disease, including diabetes a …
Developing an ecological approach to physical activity promotion in adults with Cystic fibrosis.
Shelley J, Dawson EA, Boddy LM, Stewart CE, Frost F, Nazareth D, Walshaw MJ, Knowles ZR. Shelley J, et al. Among authors: walshaw mj. PLoS One. 2022 Aug 1;17(8):e0272355. doi: 10.1371/journal.pone.0272355. eCollection 2022. PLoS One. 2022. PMID: 35914006 Free PMC article.
Increasing levels of habitual PA may be more feasible and result in greater compliance than conventional exercise training inventions which give little or no attention to long-term PA behaviour. Despite this there is limited research exploring perceptions of PA among adult …
Increasing levels of habitual PA may be more feasible and result in greater compliance than conventional exercise training inventions which …
Ivacaftor Is Associated with Reduced Lung Infection by Key Cystic Fibrosis Pathogens. A Cohort Study Using National Registry Data.
Frost FJ, Nazareth DS, Charman SC, Winstanley C, Walshaw MJ. Frost FJ, et al. Among authors: walshaw mj. Ann Am Thorac Soc. 2019 Nov;16(11):1375-1382. doi: 10.1513/AnnalsATS.201902-122OC. Ann Am Thorac Soc. 2019. PMID: 31319678
Rationale: Ivacaftor can greatly improve clinical outcomes in people with cystic fibrosis (CF) and has been shown to have in vitro antibacterial properties, yet the long-term microbiological outcomes of treatment are unknown.Objectives: To investigate changes in respirator …
Rationale: Ivacaftor can greatly improve clinical outcomes in people with cystic fibrosis (CF) and has been shown to have in vitro antibacte …
Extensive diversification is a common feature of Pseudomonas aeruginosa populations during respiratory infections in cystic fibrosis.
Ashish A, Paterson S, Mowat E, Fothergill JL, Walshaw MJ, Winstanley C. Ashish A, et al. Among authors: walshaw mj. J Cyst Fibros. 2013 Dec;12(6):790-3. doi: 10.1016/j.jcf.2013.04.003. Epub 2013 May 1. J Cyst Fibros. 2013. PMID: 23642644 Free PMC article.
BACKGROUND: Populations of the Liverpool Epidemic Strain (LES) of Pseudomonas aeruginosa undergo extensive diversification in the cystic fibrosis (CF) lung during long-term chronic infections. METHODS: We analyzed sets of 40 isolates from the sputa of five CF patients, eac …
BACKGROUND: Populations of the Liverpool Epidemic Strain (LES) of Pseudomonas aeruginosa undergo extensive diversification in the cystic fib …
Long-term effect of insulin treatment in cystic fibrosis-related diabetes.
Mohan K, Israel KL, Miller H, Grainger R, Ledson MJ, Walshaw MJ. Mohan K, et al. Among authors: walshaw mj. Respiration. 2008;76(2):181-6. doi: 10.1159/000110206. Epub 2007 Oct 25. Respiration. 2008. PMID: 17960051
BACKGROUND: Although insulin treatment confers short-term benefit in cystic fibrosis-related diabetes (CFRD), few studies have compared its long-term effect on the clinical outcome. OBJECTIVES: In this study, we aimed to investigate the long-term impact of in …
BACKGROUND: Although insulin treatment confers short-term benefit in cystic fibrosis-related diabetes (CFRD), few studies have compar …
A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance.
Salunkhe P, Smart CH, Morgan JA, Panagea S, Walshaw MJ, Hart CA, Geffers R, Tümmler B, Winstanley C. Salunkhe P, et al. Among authors: walshaw mj. J Bacteriol. 2005 Jul;187(14):4908-20. doi: 10.1128/JB.187.14.4908-4920.2005. J Bacteriol. 2005. PMID: 15995206 Free PMC article.
The LES may represent a clone with enhanced virulence and antimicrobial resistance characteristics that can vary or are lost due to mutations during long-term colonization but have contributed to the successful spread of the lineage throughout the CF population of the Unit …
The LES may represent a clone with enhanced virulence and antimicrobial resistance characteristics that can vary or are lost due to mutation …
Renal impairment in cystic fibrosis patients due to repeated intravenous aminoglycoside use.
Al-Aloul M, Miller H, Alapati S, Stockton PA, Ledson MJ, Walshaw MJ. Al-Aloul M, et al. Among authors: walshaw mj. Pediatr Pulmonol. 2005 Jan;39(1):15-20. doi: 10.1002/ppul.20138. Pediatr Pulmonol. 2005. PMID: 15521084 Clinical Trial.
Although there are reports of cases of acute renal failure occurring in cystic fibrosis (CF) patients, usually in association with the use of nephrotoxic antibiotic therapy, there have been no studies of renal function in this patient group. We hypothesized that long-term …
Although there are reports of cases of acute renal failure occurring in cystic fibrosis (CF) patients, usually in association with the use o …
13 results