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Prevalence, risk factors and outcomes of cardiac disease in cystic fibrosis: a multinational retrospective cohort study.
Frost F, Nazareth D, Fauchier L, Wat D, Shelley J, Austin P, Walshaw MJ, Lip GYH. Frost F, et al. Among authors: walshaw mj. Eur Respir J. 2023 Oct 26;62(4):2300174. doi: 10.1183/13993003.00174-2023. Print 2023 Oct. Eur Respir J. 2023. PMID: 37474158 Free PMC article.
BACKGROUND: Although people living with cystic fibrosis (PwCF) often have some risk factors for cardiovascular disease, including diabetes and chronic inflammation, little is known about the long-term cardiac risk in this condition. We aimed to determine the characteristic …
BACKGROUND: Although people living with cystic fibrosis (PwCF) often have some risk factors for cardiovascular disease, including diabetes a …
Developing an ecological approach to physical activity promotion in adults with Cystic fibrosis.
Shelley J, Dawson EA, Boddy LM, Stewart CE, Frost F, Nazareth D, Walshaw MJ, Knowles ZR. Shelley J, et al. Among authors: walshaw mj. PLoS One. 2022 Aug 1;17(8):e0272355. doi: 10.1371/journal.pone.0272355. eCollection 2022. PLoS One. 2022. PMID: 35914006 Free PMC article.
Increasing levels of habitual PA may be more feasible and result in greater compliance than conventional exercise training inventions which give little or no attention to long-term PA behaviour. Despite this there is limited research exploring perceptions of PA among adult …
Increasing levels of habitual PA may be more feasible and result in greater compliance than conventional exercise training inventions which …
Ivacaftor Is Associated with Reduced Lung Infection by Key Cystic Fibrosis Pathogens. A Cohort Study Using National Registry Data.
Frost FJ, Nazareth DS, Charman SC, Winstanley C, Walshaw MJ. Frost FJ, et al. Among authors: walshaw mj. Ann Am Thorac Soc. 2019 Nov;16(11):1375-1382. doi: 10.1513/AnnalsATS.201902-122OC. Ann Am Thorac Soc. 2019. PMID: 31319678
Rationale: Ivacaftor can greatly improve clinical outcomes in people with cystic fibrosis (CF) and has been shown to have in vitro antibacterial properties, yet the long-term microbiological outcomes of treatment are unknown.Objectives: To investigate changes in respirator …
Rationale: Ivacaftor can greatly improve clinical outcomes in people with cystic fibrosis (CF) and has been shown to have in vitro antibacte …
Evidence summary: the relationship between oral health and pulmonary disease.
Manger D, Walshaw M, Fitzgerald R, Doughty J, Wanyonyi KL, White S, Gallagher JE. Manger D, et al. Among authors: walshaw m. Br Dent J. 2017 Apr 7;222(7):527-533. doi: 10.1038/sj.bdj.2017.315. Br Dent J. 2017. PMID: 28387268 Review.
The methodology involved a streamlined rapid review process and synthesis of the data.Results The results identified a number of systematic reviews of medium to high quality which provide evidence that oral health and oral hygiene habits have an impact on incidence and outcomes o …
The methodology involved a streamlined rapid review process and synthesis of the data.Results The results identified a number of systematic …
Systematic review of the dry powder inhalers colistimethate sodium and tobramycin in cystic fibrosis.
Uttley L, Harnan S, Cantrell A, Taylor C, Walshaw M, Brownlee K, Tappenden P. Uttley L, et al. Among authors: walshaw m. Eur Respir Rev. 2013 Dec;22(130):476-86. doi: 10.1183/09059180.00001513. Eur Respir Rev. 2013. PMID: 24293463 Free PMC article. Review.
Three trials were included, and both dry powder formulations were reported to be non-inferior in the short term to nebulised tobramycin for FEV1. However, long-term follow-up data were missing and the effect on exacerbation rates was not always reported. Whilst shor …
Three trials were included, and both dry powder formulations were reported to be non-inferior in the short term to nebulised tobramyc …
Extensive diversification is a common feature of Pseudomonas aeruginosa populations during respiratory infections in cystic fibrosis.
Ashish A, Paterson S, Mowat E, Fothergill JL, Walshaw MJ, Winstanley C. Ashish A, et al. Among authors: walshaw mj. J Cyst Fibros. 2013 Dec;12(6):790-3. doi: 10.1016/j.jcf.2013.04.003. Epub 2013 May 1. J Cyst Fibros. 2013. PMID: 23642644 Free PMC article.
BACKGROUND: Populations of the Liverpool Epidemic Strain (LES) of Pseudomonas aeruginosa undergo extensive diversification in the cystic fibrosis (CF) lung during long-term chronic infections. METHODS: We analyzed sets of 40 isolates from the sputa of five CF patients, eac …
BACKGROUND: Populations of the Liverpool Epidemic Strain (LES) of Pseudomonas aeruginosa undergo extensive diversification in the cystic fib …
Long-term effect of insulin treatment in cystic fibrosis-related diabetes.
Mohan K, Israel KL, Miller H, Grainger R, Ledson MJ, Walshaw MJ. Mohan K, et al. Among authors: walshaw mj. Respiration. 2008;76(2):181-6. doi: 10.1159/000110206. Epub 2007 Oct 25. Respiration. 2008. PMID: 17960051
BACKGROUND: Although insulin treatment confers short-term benefit in cystic fibrosis-related diabetes (CFRD), few studies have compared its long-term effect on the clinical outcome. OBJECTIVES: In this study, we aimed to investigate the long-term impact of in …
BACKGROUND: Although insulin treatment confers short-term benefit in cystic fibrosis-related diabetes (CFRD), few studies have compar …
Comparison of methods of assessment of renal function in cystic fibrosis (CF) patients.
Al-Aloul M, Jackson M, Bell G, Ledson M, Walshaw M. Al-Aloul M, et al. Among authors: walshaw m. J Cyst Fibros. 2007 Jan;6(1):41-7. doi: 10.1016/j.jcf.2006.05.004. Epub 2006 Jun 27. J Cyst Fibros. 2007. PMID: 16807143 Free article.
Renal failure is increasingly being recognised in CF patients, usually as a consequence of long-term nephrotoxic therapy. There is a need for a simple method of assessment of renal function in this patient group. ...
Renal failure is increasingly being recognised in CF patients, usually as a consequence of long-term nephrotoxic therapy. There is a …
17 results