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Intragastric balloon as an adjunct to lifestyle programme in severely obese adolescents: impact on biomedical outcomes and skeletal health.
Sachdev P, Reece L, Thomson M, Natarajan A, Copeland RJ, Wales JK, Wright NP. Sachdev P, et al. Among authors: wales jk. Int J Obes (Lond). 2018 Jan;42(1):115-118. doi: 10.1038/ijo.2017.215. Epub 2017 Sep 5. Int J Obes (Lond). 2018. PMID: 28871150 Free PMC article.
Changes were not sustained at 2 years though some parameters (Diastolic BP, HBA1c, insulin AUC) demonstrated longer-term improvement despite weight regain. Despite weight loss, bone mass accrual showed age appropriate increases. In conclusion, the intragastric balloon was …
Changes were not sustained at 2 years though some parameters (Diastolic BP, HBA1c, insulin AUC) demonstrated longer-term improvement …
Adult height of preterm infants: a longitudinal cohort study.
Ferguson EC, Wright NP, Gibson AT, Carney S, Wright A, Wales JK. Ferguson EC, et al. Among authors: wales jk. Arch Dis Child. 2017 Jun;102(6):503-508. doi: 10.1136/archdischild-2016-310469. Epub 2016 Dec 20. Arch Dis Child. 2017. PMID: 27998884
RESULTS: There was no significant difference in the final height SD score (SDS) of children born at term (n=30) and those born prematurely and AGA (n=70) (0.45 term vs 0.22 preterm). ...When the difference between final height SDS and mid-parental height SDS were co …
RESULTS: There was no significant difference in the final height SD score (SDS) of children born at term (n=30) and those born premat …
Intra-gastric balloon as an adjunct to lifestyle support in severely obese adolescents; impact on weight, physical activity, cardiorespiratory fitness and psychosocial well-being.
Reece LJ, Sachdev P, Copeland RJ, Thomson M, Wales JK, Wright NP. Reece LJ, et al. Among authors: wales jk. Int J Obes (Lond). 2017 Apr;41(4):591-597. doi: 10.1038/ijo.2016.192. Epub 2016 Oct 31. Int J Obes (Lond). 2017. PMID: 27795553 Free PMC article.
CONCLUSION: An intra-gastric balloon as an adjunct to a lifestyle support programme represents a safe and well-tolerated treatment approach in severely obese adolescents, with short-term effects on weight change. Improvements in psychosocial health, physical activity and c …
CONCLUSION: An intra-gastric balloon as an adjunct to a lifestyle support programme represents a safe and well-tolerated treatment approach …
Transition in endocrinology: the challenge of maintaining continuity.
Downing J, Gleeson HK, Clayton PE, Davis JR, Wales JK, Callery P. Downing J, et al. Among authors: wales jk. Clin Endocrinol (Oxf). 2013 Jan;78(1):29-35. doi: 10.1111/j.1365-2265.2012.04473.x. Clin Endocrinol (Oxf). 2013. PMID: 22734661
Measures that promote continuity of contact could reduce the risk of long-term disengagement with care. Further development and research is required to identify the best ways to help young people with endocrine conditions in the transition from child to adult status....
Measures that promote continuity of contact could reduce the risk of long-term disengagement with care. Further development and resea …
Very low birth weight survivors have reduced peak bone mass and reduced insulin sensitivity.
Smith CM, Wright NP, Wales JK, Mackenzie C, Primhak RA, Eastell R, Walsh JS. Smith CM, et al. Among authors: wales jk. Clin Endocrinol (Oxf). 2011 Oct;75(4):443-9. doi: 10.1111/j.1365-2265.2011.04118.x. Clin Endocrinol (Oxf). 2011. PMID: 21635277
CONTEXT: Increasing numbers of very low birth weight (VLBW) infants are surviving into adulthood because of improvements in neonatal intensive care. Adverse events in early life can have long-term effects through reprogramming of metabolic systems. OBJECTIVE: To det …
CONTEXT: Increasing numbers of very low birth weight (VLBW) infants are surviving into adulthood because of improvements in neonatal …
Growth and the premature baby.
Gibson A, Carney S, Wales JK. Gibson A, et al. Among authors: wales jk. Horm Res. 2006;65 Suppl 3:75-81. doi: 10.1159/000091510. Epub 2006 Apr 10. Horm Res. 2006. PMID: 16612118 Review.
In the most immature infants, growth retardation may continue for many months and catch-up may be delayed and incomplete. Evidence from long-term studies suggests that preterm infants will be shorter and lighter than term controls and that reduced stature and head s …
In the most immature infants, growth retardation may continue for many months and catch-up may be delayed and incomplete. Evidence from long …
Thiamine-responsive megaloblastic anaemia syndrome: long-term follow-up and mutation analysis of seven families.
Ricketts CJ, Minton JA, Samuel J, Ariyawansa I, Wales JK, Lo IF, Barrett TG. Ricketts CJ, et al. Among authors: wales jk. Acta Paediatr. 2006 Jan;95(1):99-104. doi: 10.1080/08035250500323715. Acta Paediatr. 2006. PMID: 16373304
This is a unique monogenic form of vitamin-dependent diabetes for which there is limited long-term data. We aimed to study genotype-phenotype relationships and long-term follow-up in our cohort. ...
This is a unique monogenic form of vitamin-dependent diabetes for which there is limited long-term data. We aimed to study genotype-p …
Monitoring serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3), IGF-I/IGFBP-3 molar ratio and leptin during growth hormone treatment for disordered growth.
Tillmann V, Patel L, Gill MS, Whatmore AJ, Price DA, Kibirige MS, Wales JK, Clayton PE. Tillmann V, et al. Among authors: wales jk. Clin Endocrinol (Oxf). 2000 Sep;53(3):329-36. doi: 10.1046/j.1365-2265.2000.01105.x. Clin Endocrinol (Oxf). 2000. PMID: 10971450 Free article.
As a GH dose-dependent increase in serum IGF-I and IGF-I/IGFBP-3 may be associated with adverse effects, serum IGF-I and IGFBP-3 should be monitored routinely during long-term GH treatment. Serum leptin was the only variable that correlated with first year growth response …
As a GH dose-dependent increase in serum IGF-I and IGF-I/IGFBP-3 may be associated with adverse effects, serum IGF-I and IGFBP-3 should be m …
Neonatal and post-natal growth.
Gibson AT, Carney S, Cavazzoni E, Wales JK. Gibson AT, et al. Among authors: wales jk. Horm Res. 2000;53 Suppl 1:42-9. doi: 10.1159/000053204. Horm Res. 2000. PMID: 10895042 Review.
The accuracy with which such measurements are made and recorded is frequently questionable, however, and short- and medium-term changes in growth may be difficult to interpret in the light of normal variations in the pattern of growth. Infants who are small at birth …
The accuracy with which such measurements are made and recorded is frequently questionable, however, and short- and medium-term chang …
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