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The safety of repeated ketamine dosing in paediatrics: A systematic review.
James L, James IG, Wakefield J. James L, et al. Among authors: wakefield j. J Psychopharmacol. 2023 Aug;37(8):757-763. doi: 10.1177/02698811231177240. Epub 2023 Jun 2. J Psychopharmacol. 2023. PMID: 37264952 Review.
BACKGROUND: Ketamine is emerging as an effective, rapidly acting antidepressant in adult research. Hypothetical concerns about its long-term safety and impact on the developing brain are limiting its research in children. ...The longest follow-up period was 6 months. There …
BACKGROUND: Ketamine is emerging as an effective, rapidly acting antidepressant in adult research. Hypothetical concerns about its long-t
The mental health benefits of community helping during crisis: Coordinated helping, community identification and sense of unity during the COVID-19 pandemic.
Bowe M, Wakefield JRH, Kellezi B, Stevenson C, McNamara N, Jones BA, Sumich A, Heym N. Bowe M, et al. Among authors: wakefield jrh. J Community Appl Soc Psychol. 2022 May-Jun;32(3):521-535. doi: 10.1002/casp.2520. Epub 2021 Apr 5. J Community Appl Soc Psychol. 2022. PMID: 34230792 Free PMC article.
Implications for the promotion and support of voluntary helping initiatives in the context of longer-term responses to the COVID-19 pandemic are provided. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement....
Implications for the promotion and support of voluntary helping initiatives in the context of longer-term responses to the COVID-19 p …
Social Prescribing as 'Social Cure': A longitudinal study of the health benefits of social connectedness within a Social Prescribing pathway.
Wakefield JRH, Kellezi B, Stevenson C, McNamara N, Bowe M, Wilson I, Halder MM, Mair E. Wakefield JRH, et al. J Health Psychol. 2022 Feb;27(2):386-396. doi: 10.1177/1359105320944991. Epub 2020 Jul 23. J Health Psychol. 2022. PMID: 32700974 Free PMC article.
Data were collected at pathway entry from patients with long-term health conditions, or who felt isolated/lonely/anxious (N = 630), then again 4 months later (N = 178), and 6-9 months later (N = 63). ...
Data were collected at pathway entry from patients with long-term health conditions, or who felt isolated/lonely/anxious (N = 630), t …
PREDICTIVE MODELING OF CHOLERA OUTBREAKS IN BANGLADESH.
Koepke AA, Longini IM Jr, Halloran ME, Wakefield J, Minin VN. Koepke AA, et al. Among authors: wakefield j. Ann Appl Stat. 2016 Jun;10(2):575-595. doi: 10.1214/16-AOAS908. Epub 2016 Jul 22. Ann Appl Stat. 2016. PMID: 27746850 Free PMC article.
We test this method using both simulation and data from Mathbaria, Bangladesh. Parameter estimates are used to make short-term predictions that capture the formation and decline of epidemic peaks. ...
We test this method using both simulation and data from Mathbaria, Bangladesh. Parameter estimates are used to make short-term predic …
The Ran Pathway in Drosophila melanogaster Mitosis.
Chen JW, Barker AR, Wakefield JG. Chen JW, et al. Among authors: wakefield jg. Front Cell Dev Biol. 2015 Nov 26;3:74. doi: 10.3389/fcell.2015.00074. eCollection 2015. Front Cell Dev Biol. 2015. PMID: 26636083 Free PMC article. Review.
Ran-regulated pathways in mitosis bear many similarities to the well-characterized functions of Ran in nuclear transport and, as with transport, the majority of these mitotic effects are mediated through affecting the physical interaction between karyopherins and Spindle Assembly …
Ran-regulated pathways in mitosis bear many similarities to the well-characterized functions of Ran in nuclear transport and, as with transp …
Bayesian penalized spline models for the analysis of spatio-temporal count data.
Bauer C, Wakefield J, Rue H, Self S, Feng Z, Wang Y. Bauer C, et al. Among authors: wakefield j. Stat Med. 2016 May 20;35(11):1848-65. doi: 10.1002/sim.6785. Epub 2015 Nov 3. Stat Med. 2016. PMID: 26530705 Free PMC article.
The data are aggregated by geographical areas and by week, with the aims of the analysis being to gain insight into the space-time dynamics and to make short-term predictions, which will aid in the implementation of public health campaigns in those areas with a large predi …
The data are aggregated by geographical areas and by week, with the aims of the analysis being to gain insight into the space-time dynamics …
Incorporating spatial variability within epidemiological studies of environmental exposures.
Shaddick G, Lee D, Wakefield J. Shaddick G, et al. Among authors: wakefield j. Int J Appl Earth Obs Geoinf. 2013 Jun;22:65-74. doi: 10.1016/j.jag.2012.03.011. Int J Appl Earth Obs Geoinf. 2013. PMID: 25253999 Free PMC article.
In addition to simulation studies, we apply the models to a case study of the short-term effects of particulate matter on respiratory mortality using data from Greater London for the period 2002-2005....
In addition to simulation studies, we apply the models to a case study of the short-term effects of particulate matter on respiratory …
Therapeutic implications of a barrier-based pathogenesis of atopic dermatitis.
Elias PM, Wakefield JS. Elias PM, et al. Among authors: wakefield js. Clin Rev Allergy Immunol. 2011 Dec;41(3):282-95. doi: 10.1007/s12016-010-8231-1. Clin Rev Allergy Immunol. 2011. PMID: 21174234 Free PMC article. Review.
Therapeutic implications of these insights are as follows: While current therapy has been largely directed toward ameliorating Th2-mediated inflammation and/or pruritus, these therapies are fraught with short-term and potential long-term risks. In contrast, "barrier …
Therapeutic implications of these insights are as follows: While current therapy has been largely directed toward ameliorating Th2-mediated …
Long-term associations of outdoor air pollution with mortality in Great Britain.
Elliott P, Shaddick G, Wakefield JC, de Hoogh C, Briggs DJ. Elliott P, et al. Among authors: wakefield jc. Thorax. 2007 Dec;62(12):1088-94. doi: 10.1136/thx.2006.076851. Epub 2007 Jul 31. Thorax. 2007. PMID: 17666438 Free PMC article.
BACKGROUND: Recent studies have indicated long-term effects on mortality of particulate and sulphur dioxide (SO(2)) pollution, but uncertainties remain over the size of any effects, potential latency and generalisability. ...CONCLUSIONS: These findings add to the evidence …
BACKGROUND: Recent studies have indicated long-term effects on mortality of particulate and sulphur dioxide (SO(2)) pollution, but un …
17 results