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Osimertinib for Japanese patients with T790M-positive advanced non-small-cell lung cancer: A pooled subgroup analysis.
Hirashima T, Satouchi M, Hida T, Nishio M, Kato T, Sakai H, Imamura F, Kiura K, Okamoto I, Kasahara K, Uchida H, Vowler SL, Mitsudomi T. Hirashima T, et al. Among authors: vowler sl. Cancer Sci. 2019 Sep;110(9):2884-2893. doi: 10.1111/cas.14120. Epub 2019 Aug 1. Cancer Sci. 2019. PMID: 31265163 Free PMC article. Clinical Trial.
The most common all-cause adverse events (AEs) were rash (grouped term; 65.4%), diarrhea (51.9%), paronychia (grouped term; 49.4%), and dry skin (grouped term; 39.5%). ...
The most common all-cause adverse events (AEs) were rash (grouped term; 65.4%), diarrhea (51.9%), paronychia (grouped term; 49 …
Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study.
Ross-Adams H, Lamb AD, Dunning MJ, Halim S, Lindberg J, Massie CM, Egevad LA, Russell R, Ramos-Montoya A, Vowler SL, Sharma NL, Kay J, Whitaker H, Clark J, Hurst R, Gnanapragasam VJ, Shah NC, Warren AY, Cooper CS, Lynch AG, Stark R, Mills IG, Grönberg H, Neal DE; CamCaP Study Group. Ross-Adams H, et al. Among authors: vowler sl. EBioMedicine. 2015 Jul 29;2(9):1133-44. doi: 10.1016/j.ebiom.2015.07.017. eCollection 2015 Sep. EBioMedicine. 2015. PMID: 26501111 Free PMC article.
These subgroups were able to consistently predict biochemical relapse (p = 0.0017 and p = 0.016 respectively) and were further validated in a third cohort with long-term follow-up (p = 0.027). We show the relative contributions of gene expression and copy number data on ph …
These subgroups were able to consistently predict biochemical relapse (p = 0.0017 and p = 0.016 respectively) and were further validated in …
Cognition, continence and transfer status at the time of discharge from an acute hospital setting and their associations with an unfavourable discharge outcome after stroke.
Myint PK, Vowler SL, Redmayne O, Fulcher RA. Myint PK, et al. Among authors: vowler sl. Gerontology. 2008;54(4):202-9. doi: 10.1159/000126491. Epub 2008 Apr 11. Gerontology. 2008. PMID: 18408357
Consecutive acute stroke admissions between 1997 and 2003 who were discharged alive were identified and the likelihood of adverse discharge outcomes defined as institutionalization or a requirement for longer-term rehabilitation was estimated. RESULTS: A total of 2,521 dis …
Consecutive acute stroke admissions between 1997 and 2003 who were discharged alive were identified and the likelihood of adverse discharge …
A 5-year observational study of the outcome in pediatric cholesteatoma surgery.
Yung M, Jacobsen NL, Vowler SL. Yung M, et al. Among authors: vowler sl. Otol Neurotol. 2007 Dec;28(8):1038-40. doi: 10.1097/mao.0b013e318159e799. Otol Neurotol. 2007. PMID: 17971719
CONCLUSION: Currently, there is no consensus on how outcomes of cholesteatoma surgery are reported. The authors recommend that these should be long-term data (5 yr or longer), using survival analyses for recidivistic rate and cutoff analyses for postoperative otorrhea and …
CONCLUSION: Currently, there is no consensus on how outcomes of cholesteatoma surgery are reported. The authors recommend that these should …
Long-term results in ossiculoplasty: an analysis of prognostic factors.
Yung M, Vowler SL. Yung M, et al. Among authors: vowler sl. Otol Neurotol. 2006 Sep;27(6):874-81. doi: 10.1097/01.mao.0000226305.43951.13. Otol Neurotol. 2006. PMID: 16788423
Absent malleus and otorrhea are important unfavorable factors for short-term outcome in ossiculoplasty (6 months), whereas absent malleus is the only important unfavorable factor for long-term outcome in ossiculoplasty (5 years)....
Absent malleus and otorrhea are important unfavorable factors for short-term outcome in ossiculoplasty (6 months), whereas absent mal …
Utilisation of diagnostic computerised tomography imaging and immediate clinical outcomes in older people with stroke before and after introduction of the National Service Framework for older people. A comparative study of hospital-based stroke registry data (1997-2003): Norfolk experience.
Myint PK, Vowler SL, Redmayne O, Fulcher RA. Myint PK, et al. Among authors: vowler sl. Age Ageing. 2006 Jul;35(4):399-403. doi: 10.1093/ageing/afl030. Age Ageing. 2006. PMID: 16788080
Continual monitoring using stroke registry data may help to assess whether these effects are sustained in the longer term....
Continual monitoring using stroke registry data may help to assess whether these effects are sustained in the longer term....
Effect of acid suppression on molecular predictors for esophageal cancer.
Lao-Sirieix P, Roy A, Worrall C, Vowler SL, Gardiner S, Fitzgerald RC. Lao-Sirieix P, et al. Among authors: vowler sl. Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):288-93. doi: 10.1158/1055-9965.EPI-05-0528. Cancer Epidemiol Biomarkers Prev. 2006. PMID: 16492917
Acid suppression had no effect on c-myc or apoptosis. CONCLUSION: Long-term acid suppression reduces proliferation in Barrett's esophagus samples but has no advantageous effect on c-myc, apoptosis, or COX-2....
Acid suppression had no effect on c-myc or apoptosis. CONCLUSION: Long-term acid suppression reduces proliferation in Barrett's esoph …