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Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.
Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, Ventetuolo CE, Vieillard-Baron A, Voelkel NF, Vonk-Noordegraaf A, Hassoun PM; American Thoracic Society Assembly on Pulmonary Circulation. Lahm T, et al. Among authors: voelkel nf. Am J Respir Crit Care Med. 2018 Aug 15;198(4):e15-e43. doi: 10.1164/rccm.201806-1160ST. Am J Respir Crit Care Med. 2018. PMID: 30109950 Free PMC article.
BACKGROUND: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short- and long-term outcomes. Although remarkable progress has been made in the understanding of RV function and failure since the meeting o …
BACKGROUND: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive syndromes is a significant determinant of short- a …
'End-stage' heart failure therapy: potential lessons from congenital heart disease: from pulmonary artery banding and interatrial communication to parallel circulation.
Schranz D, Akintuerk H, Voelkel NF. Schranz D, et al. Among authors: voelkel nf. Heart. 2017 Feb 15;103(4):262-267. doi: 10.1136/heartjnl-2015-309110. Epub 2016 Dec 23. Heart. 2017. PMID: 28011759 Free PMC article. Review.
Therefore, novel therapeutical strategies are needed. Based on pathophysiological insights regarding (1) the long-term impact of an obstructive pulmonary outflow tract in neonates with congenitally corrected transposition of the great arteries, (2) the importance of a rest …
Therefore, novel therapeutical strategies are needed. Based on pathophysiological insights regarding (1) the long-term impact of an o …
"Nihilism" of chronic heart failure therapy in children and why effective therapy is withheld.
Schranz D, Voelkel NF. Schranz D, et al. Among authors: voelkel nf. Eur J Pediatr. 2016 Apr;175(4):445-55. doi: 10.1007/s00431-016-2700-3. Epub 2016 Feb 19. Eur J Pediatr. 2016. PMID: 26895877 Free PMC article. Review.
Chronic therapy with long-acting diuretics and fluid restriction are not advocated because short-term effects are achieved at the expense of further neuro-humoral stimulation. It remains unclear why diuretics are recommended although evidence-based studies, documenting lon …
Chronic therapy with long-acting diuretics and fluid restriction are not advocated because short-term effects are achieved at the exp …
Treatment for pulmonary arterial hypertension-associated right ventricular dysfunction.
Gomez-Arroyo J, Sandoval J, Simon MA, Dominguez-Cano E, Voelkel NF, Bogaard HJ. Gomez-Arroyo J, et al. Among authors: voelkel nf. Ann Am Thorac Soc. 2014 Sep;11(7):1101-15. doi: 10.1513/AnnalsATS.201312-425FR. Ann Am Thorac Soc. 2014. PMID: 25079379 Review.
Although this may initially improve cardiac performance, the long-term effects on myocardial oxygen consumption and function are unclear. ...
Although this may initially improve cardiac performance, the long-term effects on myocardial oxygen consumption and function are uncl …
A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects.
Gomez-Arroyo J, Saleem SJ, Mizuno S, Syed AA, Bogaard HJ, Abbate A, Taraseviciene-Stewart L, Sung Y, Kraskauskas D, Farkas D, Conrad DH, Nicolls MR, Voelkel NF. Gomez-Arroyo J, et al. Among authors: voelkel nf. Am J Physiol Lung Cell Mol Physiol. 2012 May 15;302(10):L977-91. doi: 10.1152/ajplung.00362.2011. Epub 2012 Feb 3. Am J Physiol Lung Cell Mol Physiol. 2012. PMID: 22307907 Free PMC article. Review.
Many chronic pulmonary diseases are associated with pulmonary hypertension (PH) and pulmonary vascular remodeling, which is a term that continues to be used to describe a wide spectrum of vascular abnormalities. ...
Many chronic pulmonary diseases are associated with pulmonary hypertension (PH) and pulmonary vascular remodeling, which is a term th …
COPD/emphysema: The vascular story.
Voelkel NF, Gomez-Arroyo J, Mizuno S. Voelkel NF, et al. Pulm Circ. 2011 Jul-Sep;1(3):320-6. doi: 10.4103/2045-8932.87295. Pulm Circ. 2011. PMID: 22140621 Free PMC article.
We propose that a "sick lung circulation" rather than the right heart afterload may better explain the cardiac abnormalities in COPD patients which are usually summarized with the term "cor pulmonale." The mechanisms and causes of pulmonary hypertension are likely complex …
We propose that a "sick lung circulation" rather than the right heart afterload may better explain the cardiac abnormalities in COPD patient …
Human Immunodeficiency Virus nef signature sequences are associated with pulmonary hypertension.
Almodovar S, Knight R, Allshouse AA, Roemer S, Lozupone C, McDonald D, Widmann J, Voelkel NF, Shelton RJ, Suarez EB, Hammer KW, Goujard C, Petrosillo N, Simonneau G, Hsue PY, Humbert M, Flores SC. Almodovar S, et al. Among authors: voelkel nf. AIDS Res Hum Retroviruses. 2012 Jun;28(6):607-18. doi: 10.1089/AID.2011.0021. Epub 2012 Jan 17. AIDS Res Hum Retroviruses. 2012. PMID: 22066947 Free PMC article.
Severe pulmonary hypertension (PH) associated with vascular remodeling is a long-term complication of HIV infection (HIV-PH) affecting 1/200 infected individuals vs. 1/200,000 frequency in the uninfected population. ...
Severe pulmonary hypertension (PH) associated with vascular remodeling is a long-term complication of HIV infection (HIV-PH) affectin …
Endothelial cells and pulmonary arterial hypertension: apoptosis, proliferation, interaction and transdifferentiation.
Sakao S, Tatsumi K, Voelkel NF. Sakao S, et al. Among authors: voelkel nf. Respir Res. 2009 Oct 13;10(1):95. doi: 10.1186/1465-9921-10-95. Respir Res. 2009. PMID: 19825167 Free PMC article. Review.
In this article, we review pathogenetic concepts of severe pulmonary arterial hypertension and explain the term "complex vascular lesion ", commonly named "plexiform lesion", with endothelial cell dysfunction, i.e., apoptosis, proliferation, interaction with smooth muscle …
In this article, we review pathogenetic concepts of severe pulmonary arterial hypertension and explain the term "complex vascular les …
Estrogen exposure, obesity and thyroid disease in women with severe pulmonary hypertension.
Sweeney L, Voelkel NF. Sweeney L, et al. Among authors: voelkel nf. Eur J Med Res. 2009 Sep 28;14(10):433-42. doi: 10.1186/2047-783x-14-10-433. Eur J Med Res. 2009. PMID: 19748850 Free PMC article.
In particular, no studies have attempted to evaluate for concurrent thyroid disease, obesity and long-term estrogen exposure in patients. 88 patients attending the Pulmonary Hypertension Association 8th International meeting completed a questionnaire and were interviewed. …
In particular, no studies have attempted to evaluate for concurrent thyroid disease, obesity and long-term estrogen exposure in patie …
Pulmonary arterial hypertension and its association with HIV infection: an overview.
Lederman MM, Sereni D, Simonneau G, Voelkel NF. Lederman MM, et al. Among authors: voelkel nf. AIDS. 2008 Sep;22 Suppl 3:S1-6. doi: 10.1097/01.aids.0000327509.30385.3b. AIDS. 2008. PMID: 18845916 Review.
With this improvement in survival has come an increasing recognition of the importance of many long-term sequelae of subclinical immune deficiency and the attendant immune activation that characterize HIV infection. ...
With this improvement in survival has come an increasing recognition of the importance of many long-term sequelae of subclinical immu …
18 results