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Short-term deceleration capacity of heart rate: a sensitive marker of cardiac autonomic dysfunction in idiopathic Parkinson's disease.
Carricarte Naranjo C, Marras C, Visanji NP, Cornforth DJ, Sanchez-Rodriguez L, Schüle B, Goldman SM, Estévez M, Stein PK, Lang AE, Jelinek HF, Machado A. Carricarte Naranjo C, et al. Among authors: visanji np. Clin Auton Res. 2021 Dec;31(6):729-736. doi: 10.1007/s10286-021-00815-4. Epub 2021 Jul 12. Clin Auton Res. 2021. PMID: 34251546
CONCLUSIONS: Deceleration-related oscillations of HRV were significantly reduced in the older PD patients compared to healthy controls, suggesting that short-term DC may be a sensitive marker of cardiac autonomic dysfunction in PD. DC may be complementary to traditional ma …
CONCLUSIONS: Deceleration-related oscillations of HRV were significantly reduced in the older PD patients compared to healthy controls, sugg …
Increased markers of cardiac vagal activity in leucine-rich repeat kinase 2-associated Parkinson's disease.
Carricarte Naranjo C, Marras C, Visanji NP, Cornforth DJ, Sanchez-Rodriguez L, Schüle B, Goldman SM, Estévez M, Stein PK, Lang AE, Jelinek HF, Machado A. Carricarte Naranjo C, et al. Among authors: visanji np. Clin Auton Res. 2019 Dec;29(6):603-614. doi: 10.1007/s10286-019-00632-w. Epub 2019 Aug 23. Clin Auton Res. 2019. PMID: 31444591
We aimed to assess cardiac autonomic modulation through standard and novel approaches to HRV analysis in individuals who carry the LRRK2 G2019S mutation. METHODS: Short-term electrocardiograms were recorded in 14 LRRK2-associated PD patients, 25 LRRK2-non-manifesting carri …
We aimed to assess cardiac autonomic modulation through standard and novel approaches to HRV analysis in individuals who carry the LRRK2 G20 …
Dopamine D3 receptor stimulation underlies the development of L-DOPA-induced dyskinesia in animal models of Parkinson's disease.
Visanji NP, Fox SH, Johnston T, Reyes G, Millan MJ, Brotchie JM. Visanji NP, et al. Neurobiol Dis. 2009 Aug;35(2):184-92. doi: 10.1016/j.nbd.2008.11.010. Epub 2008 Dec 9. Neurobiol Dis. 2009. PMID: 19118628
Development of L-DOPA-induced dyskinesia (LID) remains a major problem in the long-term treatment of Parkinson's disease (PD). Sensitization to L-DOPA correlates with ectopic expression of D3 dopamine receptors in the striatum, implicating D3 receptors in development of LI …
Development of L-DOPA-induced dyskinesia (LID) remains a major problem in the long-term treatment of Parkinson's disease (PD). Sensit …