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Spatial effects in modeling pharmacokinetics of rapid action drugs.
Bull Math Biol. 2002 May;64(3):483-500. doi: 10.1006/bulm.2001.0281.
Bull Math Biol. 2002.
PMID: 12094406
This model, which overcomes the limitations of the classical compartment models routinely used in pharmacokinetics, incorporates spatial effects due to heterogeneity in the circulation: it takes the form of a dispersion equation on a circular domain, with a time-dependent leakage …
This model, which overcomes the limitations of the classical compartment models routinely used in pharmacokinetics, incorporates spatial eff …
Clinical pharmacokinetics of neuromuscular relaxants in pregnancy.
Guay J, Grenier Y, Varin F.
Guay J, et al. Among authors: varin f.
Clin Pharmacokinet. 1998 Jun;34(6):483. doi: 10.2165/00003088-199834060-00004.
Clin Pharmacokinet. 1998.
PMID: 9646009
Review.
This may be explained by the increased glomerular filtration rate reported in pregnant women. The clinical duration of vecuronium in term and postpartum women is twice that reported in nonpregnant women. ...
This may be explained by the increased glomerular filtration rate reported in pregnant women. The clinical duration of vecuronium in term …
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