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Ageing is reversed, and metabolism is reset to young levels in recovering dauer larvae of C. elegans.
Houthoofd K, Braeckman BP, Lenaerts I, Brys K, De Vreese A, Van Eygen S, Vanfleteren JR. Houthoofd K, et al. Among authors: vanfleteren jr. Exp Gerontol. 2002 Aug-Sep;37(8-9):1015-21. doi: 10.1016/s0531-5565(02)00063-3. Exp Gerontol. 2002. PMID: 12213552
We have investigated physiological changes associated with long-term diapause survival, and found that dauer larvae slowly develop senescence-like symptoms, including decrease of metabolic capacity, aconitase enzyme activity, and ATP stores, and increase of lipofuscin- and …
We have investigated physiological changes associated with long-term diapause survival, and found that dauer larvae slowly develop se …
Modulation of kinase activities in dauers and in long-lived mutants of Caenorhabditis elegans.
Vanfleteren JR, De Vreese A. Vanfleteren JR, et al. J Gerontol A Biol Sci Med Sci. 1997 Jul;52(4):B212-6. doi: 10.1093/gerona/52a.4.b212. J Gerontol A Biol Sci Med Sci. 1997. PMID: 9224426
Elevated levels of PKA and PTK were also present in dauer larvae, developmentally arrested juveniles specialized for long-term survival, relative to L3 larvae, the alternative developmental stage. ...
Elevated levels of PKA and PTK were also present in dauer larvae, developmentally arrested juveniles specialized for long-term surviv …