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Clinical, serological and DNA testing in Bengo Province, Angola further reveals low filarial endemicity and opportunities for disease elimination.
Paulo R, Brito M, Van-Dunem P, Martins A, Novak RJ, Jacob B, Molyneux DM, Unnasch TR, Stothard JR, Kelly-Hope L. Paulo R, et al. Among authors: unnasch tr. Parasite Epidemiol Control. 2020 Sep 23;11:e00183. doi: 10.1016/j.parepi.2020.e00183. eCollection 2020 Nov. Parasite Epidemiol Control. 2020. PMID: 33072898 Free PMC article.
For L. loa, 6.2% (n = 100/16616) individuals were found to have eyeworm, based on the rapid assessment procedure for loiasis (RAPLOA) surveys, and 11.5% (n =178/1543) based on nested PCR analyses of venous blood. L. loa prevalences in long-term residents (>10 years) and …
For L. loa, 6.2% (n = 100/16616) individuals were found to have eyeworm, based on the rapid assessment procedure for loiasis (RAPLOA) survey …
Distinct effects of acute versus chronic corticosterone exposure on Zebra finch responses to West Nile virus.
Martin LB, Kernbach ME, Unnasch TR. Martin LB, et al. Among authors: unnasch tr. Conserv Physiol. 2019 Dec 5;7(1):coz094. doi: 10.1093/conphys/coz094. eCollection 2019. Conserv Physiol. 2019. PMID: 31824675 Free PMC article.
Wild animals are exposed to both short- (acute) and long-term (chronic) stressors. The glucocorticoid hormones, such as corticosterone (CORT), facilitate coping with such stressors, but these hormones can have quite distinct effects contingent on the duration of their elev …
Wild animals are exposed to both short- (acute) and long-term (chronic) stressors. The glucocorticoid hormones, such as corticosteron …
Large-Scale Complete-Genome Sequencing and Phylodynamic Analysis of Eastern Equine Encephalitis Virus Reveals Source-Sink Transmission Dynamics in the United States.
Tan Y, Lam TT, Heberlein-Larson LA, Smole SC, Auguste AJ, Hennigan S, Halpin RA, Fedorova N, Puri V, Stockwell TB, Shilts MH, Andreadis T, Armstrong PM, Tesh RB, Weaver SC, Unnasch TR, Ciota AT, Kramer LD, Das SR. Tan Y, et al. Among authors: unnasch tr. J Virol. 2018 May 29;92(12):e00074-18. doi: 10.1128/JVI.00074-18. Print 2018 Jun 15. J Virol. 2018. PMID: 29618651 Free PMC article.
Phylogenetic analysis suggested EEEV evolves relatively slowly and that transmission is enzootic in Florida, characterized by higher genetic diversity and long-term local persistence. In contrast, EEEV strains in New York and Massachusetts were characterized by lower genet …
Phylogenetic analysis suggested EEEV evolves relatively slowly and that transmission is enzootic in Florida, characterized by higher genetic …
Interruption of the transmission of Onchocerca volvulus in the Kashoya-Kitomi focus, western Uganda by long-term ivermectin treatment and elimination of the vector Simulium neavei by larviciding.
Lakwo T, Garms R, Wamani J, Tukahebwa EM, Byamukama E, Onapa AW, Tukesiga E, Katamanywa J, Begumisa S, Habomugisha P, Oguttu D, Byamukama E, Richards F, Unnasch TR, Katabarwa M. Lakwo T, et al. Among authors: unnasch tr. Acta Trop. 2017 Mar;167:128-136. doi: 10.1016/j.actatropica.2016.12.029. Epub 2016 Dec 26. Acta Trop. 2017. PMID: 28034767
Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont.
Bennuru S, Cotton JA, Ribeiro JM, Grote A, Harsha B, Holroyd N, Mhashilkar A, Molina DM, Randall AZ, Shandling AD, Unnasch TR, Ghedin E, Berriman M, Lustigman S, Nutman TB. Bennuru S, et al. Among authors: unnasch tr. mBio. 2016 Nov 23;7(6):e02028-16. doi: 10.1128/mBio.02028-16. mBio. 2016. PMID: 27881553 Free PMC article.
Onchocerciasis (river blindness) is a neglected tropical disease that has been successfully targeted by mass drug treatment programs in the Americas and small parts of Africa. Achieving the long-term goal of elimination of onchocerciasis, however, requires additional tools …
Onchocerciasis (river blindness) is a neglected tropical disease that has been successfully targeted by mass drug treatment programs in the …
Interruption of Onchocerca volvulus transmission in the Abu Hamed focus, Sudan.
Higazi TB, Zarroug IM, Mohamed HA, Elmubark WA, Deran TC, Aziz N, Katabarwa M, Hassan HK, Unnasch TR, Mackenzie CD, Richards F, Hashim K. Higazi TB, et al. Among authors: unnasch tr. Am J Trop Med Hyg. 2013 Jul;89(1):51-7. doi: 10.4269/ajtmh.13-0112. Epub 2013 May 20. Am J Trop Med Hyg. 2013. PMID: 23690554 Free PMC article.
Because this assessment of the focus meets the 2001 World Health Organization (WHO) criteria for interrupted transmission, treatment was halted in 2012, and a post-treatment surveillance period was initiated in anticipation of declaration of disease elimination in this area. We p …
Because this assessment of the focus meets the 2001 World Health Organization (WHO) criteria for interrupted transmission, treatment was hal …
Pool screen polymerase chain reaction for estimating the prevalence of Onchocerca volvulus infection in Simulium damnosum sensu lato: results of a field trial in an area subject to successful vector control.
Yamèogo L, Toè L, Hougard JM, Boatin BA, Unnasch TR. Yamèogo L, et al. Among authors: unnasch tr. Am J Trop Med Hyg. 1999 Jan;60(1):124-8. doi: 10.4269/ajtmh.1999.60.124. Am J Trop Med Hyg. 1999. PMID: 9988335
Here, we report a method of restricting the pool screen PCR assay to infectious parasites and the results of a field test in an area subject to long-term vector control. The prevalence of infection determined by dissection did not differ from that determined by pool screen …
Here, we report a method of restricting the pool screen PCR assay to infectious parasites and the results of a field test in an area subject …