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Endocrine-sensitive physical endpoints in newborns: ranges and predictors.
Shah R, Alshaikh B, Schall JI, Kelly A, Ford E, Zemel BS, Umbach DM, Adgent M, Stallings VA. Shah R, et al. Among authors: umbach dm. Pediatr Res. 2021 Feb;89(3):660-666. doi: 10.1038/s41390-020-0950-2. Epub 2020 May 12. Pediatr Res. 2021. PMID: 32396926 Free PMC article.
Studies using standardized measurement techniques that describe demographic and clinical variability in these endpoints are lacking. METHODS: Three hundred and eighty-eight healthy term newborns <3 days old were evaluated, 69% African American and 25% White. ...
Studies using standardized measurement techniques that describe demographic and clinical variability in these endpoints are lacking. METHODS …
Characterization of ovarian development in girls from birth to 9 months.
Chin HB, Baird DD, Kaplan SL, Darge K, Adgent MA, Ford EG, Rogan WJ, Stallings VA, Umbach DM. Chin HB, et al. Among authors: umbach dm. Paediatr Perinat Epidemiol. 2021 Jan;35(1):75-82. doi: 10.1111/ppe.12673. Epub 2020 Apr 13. Paediatr Perinat Epidemiol. 2021. PMID: 32285479 Free PMC article.
Results from the estimated overall ovarian growth trajectory show that ovarian volume increases more than sixfold during the first 16 weeks after birth and then remains relatively stable in the later weeks of infancy. ...This research contributes to future development of r …
Results from the estimated overall ovarian growth trajectory show that ovarian volume increases more than sixfold during the first 16 weeks …
Incidental findings during ultrasound of thyroid, breast, testis, uterus and ovary in healthy term neonates.
Calle-Toro JS, Kelly A, Ford EJ, Zemel BS, Schall JI, Adgent MA, Umbach DM, Rogan WJ, Stallings VA, Darge K, Kaplan SL. Calle-Toro JS, et al. Among authors: umbach dm. J Ultrasound. 2019 Sep;22(3):395-400. doi: 10.1007/s40477-019-00365-6. Epub 2019 Feb 27. J Ultrasound. 2019. PMID: 30811014 Free PMC article.
We describe ultrasound features in thyroid, breast buds, testes, uterus, and ovaries in infants up to 32 weeks old that vary from the expected tissue architecture. Infants described in this paper were enrolled as healthy term neonates in a longitudinal study of normal feed …
We describe ultrasound features in thyroid, breast buds, testes, uterus, and ovaries in infants up to 32 weeks old that vary from the expect …
Incident thyroid disease in female spouses of private pesticide applicators.
Shrestha S, Parks CG, Goldner WS, Kamel F, Umbach DM, Ward MH, Lerro CC, Koutros S, Hofmann JN, Beane Freeman LE, Sandler DP. Shrestha S, et al. Among authors: umbach dm. Environ Int. 2018 Sep;118:282-292. doi: 10.1016/j.envint.2018.05.041. Epub 2018 Jun 13. Environ Int. 2018. PMID: 29908479 Free PMC article.
Conversely, the insecticide phorate, and the herbicides imazethapyr and metolachlor were associated with decreased risk (HR ranging 0.63-0.73), as were long-term farm residence and other farm-related activities (HR ranging 0.69-0.84). ...
Conversely, the insecticide phorate, and the herbicides imazethapyr and metolachlor were associated with decreased risk (HR ranging 0.63-0.7 …
Military service, deployments, and exposures in relation to amyotrophic lateral sclerosis survival.
Beard JD, Engel LS, Richardson DB, Gammon MD, Baird C, Umbach DM, Allen KD, Stanwyck CL, Keller J, Sandler DP, Schmidt S, Kamel F. Beard JD, et al. Among authors: umbach dm. PLoS One. 2017 Oct 10;12(10):e0185751. doi: 10.1371/journal.pone.0185751. eCollection 2017. PLoS One. 2017. PMID: 29016608 Free PMC article.
We also used inverse probability weights to adjust for potential selection bias among a case group that included a disproportionate number of long-term survivors at enrollment. RESULTS: We observed 446 deaths during 24,267 person-months of follow-up (median follow-up: 28 m …
We also used inverse probability weights to adjust for potential selection bias among a case group that included a disproportionate number o …
Size of testes, ovaries, uterus and breast buds by ultrasound in healthy full-term neonates ages 0-3 days.
Kaplan SL, Edgar JC, Ford EG, Adgent MA, Schall JI, Kelly A, Umbach DM, Rogan WJ, Stallings VA, Darge K. Kaplan SL, et al. Among authors: umbach dm. Pediatr Radiol. 2016 Dec;46(13):1837-1847. doi: 10.1007/s00247-016-3681-0. Epub 2016 Aug 31. Pediatr Radiol. 2016. PMID: 27580909 Free PMC article.
BACKGROUND: Hormonally sensitive organs in the neonate can change size within days of birth as circulating maternal estrogen wanes. Although several reports document the size of these organs through infancy, few focus attention on the near-birth period. ...OBJECTIVE …
BACKGROUND: Hormonally sensitive organs in the neonate can change size within days of birth as circulating maternal estrogen wanes. A …
Military service, deployments, and exposures in relation to amyotrophic lateral sclerosis etiology.
Beard JD, Engel LS, Richardson DB, Gammon MD, Baird C, Umbach DM, Allen KD, Stanwyck CL, Keller J, Sandler DP, Schmidt S, Kamel F. Beard JD, et al. Among authors: umbach dm. Environ Int. 2016 May;91:104-15. doi: 10.1016/j.envint.2016.02.014. Epub 2016 Feb 23. Environ Int. 2016. PMID: 26923711 Free PMC article.
We used inverse probability weighting to adjust for potential bias from confounding, missing covariate data, and selection arising from a case group that disproportionately included long-term survivors and a control group that may or may not differ from U.S. military veter …
We used inverse probability weighting to adjust for potential bias from confounding, missing covariate data, and selection arising from a ca …
Urogenital epithelial cells as simple markers of estrogen response in infants: methods and applications.
Adgent MA, Flake GP, Umbach DM, Stallings VA, Bernbaum JC, Rogan WJ. Adgent MA, et al. Among authors: umbach dm. PLoS One. 2013 Oct 16;8(10):e77061. doi: 10.1371/journal.pone.0077061. eCollection 2013. PLoS One. 2013. PMID: 24146956 Free PMC article.
For example, growth of reproductive organs may be susceptible to estrogenic chemicals, but measuring it requires skilled ultrasound examination; timing of pubertal onset may be altered, but observing it requires long-term follow up. To address the need for a simple marker …
For example, growth of reproductive organs may be susceptible to estrogenic chemicals, but measuring it requires skilled ultrasound examinat …
US assessment of estrogen-responsive organ growth among healthy term infants: piloting methods for assessing estrogenic activity.
Nguyen RH, Umbach DM, Parad RB, Stroehla B, Rogan WJ, Estroff JA. Nguyen RH, et al. Among authors: umbach dm. Pediatr Radiol. 2011 May;41(5):633-42. doi: 10.1007/s00247-010-1895-0. Epub 2010 Nov 23. Pediatr Radiol. 2011. PMID: 21104239 Free PMC article.
OBJECTIVE: We evaluated ultrasonography for monitoring growth of multiple estrogen-responsive organs in healthy infants and developed organ-growth trajectories. MATERIALS AND METHODS: We studied 38 boys (61 visits) from birth to age 6 months and 41 girls (96 visits) from …
OBJECTIVE: We evaluated ultrasonography for monitoring growth of multiple estrogen-responsive organs in healthy infants and developed organ- …
Smoking duration, intensity, and risk of Parkinson disease.
Chen H, Huang X, Guo X, Mailman RB, Park Y, Kamel F, Umbach DM, Xu Q, Hollenbeck A, Schatzkin A, Blair A. Chen H, et al. Among authors: umbach dm. Neurology. 2010 Mar 16;74(11):878-84. doi: 10.1212/WNL.0b013e3181d55f38. Epub 2010 Mar 10. Neurology. 2010. PMID: 20220126 Free PMC article.
Close examination of smoking behaviors in early life showed that patients with PD were less likely to be smokers at each age period, but if they smoked, they smoked similar numbers of cigarettes per day as individuals without PD. CONCLUSIONS: This large study suggests that long- …
Close examination of smoking behaviors in early life showed that patients with PD were less likely to be smokers at each age period, but if …
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