Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression.
Xhonneux LP, Knight O, Lernmark Å, Bonifacio E, Hagopian WA, Rewers MJ, She JX, Toppari J, Parikh H, Smith KGC, Ziegler AG, Akolkar B, Krischer JP, McKinney EF.
Xhonneux LP, et al.
Sci Transl Med. 2021 Mar 31;13(587):eabd5666. doi: 10.1126/scitranslmed.abd5666.
Sci Transl Med. 2021.
PMID: 33790023
Free PMC article.
The number, type, and titer of islet autoantibodies are associated with long-term disease risk but do not cause disease, and robust early predictors of individual progression to T1D onset remain elusive. ...
The number, type, and titer of islet autoantibodies are associated with long-term disease risk but do not cause disease, and robust e …