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52 results

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Page 1
Lower Neurocognitive Functioning in HIV-Exposed Uninfected Children Compared With That in HIV-Unexposed Children.
Benki-Nugent SF, Yunusa R, Mueni A, Laboso T, Tamasha N, Njuguna I, Gómez L, Wamalwa DC, Tapia K, Maleche-Obimbo E, Bangirana P, Boivin MJ, John-Stewart GC. Benki-Nugent SF, et al. J Acquir Immune Defic Syndr. 2022 Apr 1;89(4):441-447. doi: 10.1097/QAI.0000000000002881. J Acquir Immune Defic Syndr. 2022. PMID: 35202050 Free PMC article.
In analyses adjusted for child's age and sex and caregiver's age, education, and household rent, CHEU had significantly lower mean z scores for global cognitive ability than CHUU [-0.35, 95% confidence interval (CI): -0.64 to -0.05; P = 0.02], short-term memory (-0.44, 95% …
In analyses adjusted for child's age and sex and caregiver's age, education, and household rent, CHEU had significantly lower mean z scores …
High Plasma Soluble CD163 During Infancy Is a Marker for Neurocognitive Outcomes in Early-Treated HIV-Infected Children.
Benki-Nugent SF, Martopullo I, Laboso T, Tamasha N, Wamalwa DC, Tapia K, Langat A, Maleche-Obimbo E, Marra CM, Bangirana P, Boivin MJ, John-Stewart GC. Benki-Nugent SF, et al. J Acquir Immune Defic Syndr. 2019 May 1;81(1):102-109. doi: 10.1097/QAI.0000000000001979. J Acquir Immune Defic Syndr. 2019. PMID: 30768490 Free PMC article.
We examined the relation between monocyte activation markers and early and long-term neurodevelopmental outcomes in early-treated HIV-infected children. ...After ART and viral suppression, monocyte activation may predict worse short- and long-term neurodevelopment o …
We examined the relation between monocyte activation markers and early and long-term neurodevelopmental outcomes in early-treated HIV …
Focal Brain Injury Associated with a Model of Severe Hypoxic-Ischemic Encephalopathy in Nonhuman Primates.
McAdams RM, McPherson RJ, Kapur RP, Juul SE. McAdams RM, et al. Dev Neurosci. 2017;39(1-4):107-123. doi: 10.1159/000456658. Epub 2017 Mar 25. Dev Neurosci. 2017. PMID: 28343228 Free PMC article.
To better understand the mechanisms contributing to brain injury and improve outcomes in neonates with HIE, better preclinical animal models that mimic the clinical situation following birth asphyxia in term newborns are needed. In an effort to achieve this goal, we …
To better understand the mechanisms contributing to brain injury and improve outcomes in neonates with HIE, better preclinical animal models …
Serial plasma metabolites following hypoxic-ischemic encephalopathy in a nonhuman primate model.
Chun PT, McPherson RJ, Marney LC, Zangeneh SZ, Parsons BA, Shojaie A, Synovec RE, Juul SE. Chun PT, et al. Dev Neurosci. 2015;37(2):161-71. doi: 10.1159/000370147. Epub 2015 Feb 27. Dev Neurosci. 2015. PMID: 25765047 Free PMC article.
Further comparison determined that 8 metabolites (arachidonic acid, butanoic acid, citric acid, fumaric acid, lactate, malate, propanoic acid, and succinic acid) correlated with early and/or long-term neurodevelopmental outcomes. The combined outcomes of death or cerebral …
Further comparison determined that 8 metabolites (arachidonic acid, butanoic acid, citric acid, fumaric acid, lactate, malate, propanoic aci …
Volitional muscle activity paired with transcranial magnetic stimulation increases corticospinal excitability.
Edwardson MA, Avery DH, Fetz EE. Edwardson MA, et al. Front Neurosci. 2015 Jan 12;8:442. doi: 10.3389/fnins.2014.00442. eCollection 2014. Front Neurosci. 2015. PMID: 25628525 Free PMC article.
Studies of activity-dependent stimulation in non-human primates suggest that pairing each instance of volitional muscle activity with immediate intracortical stimulation causes long-term-potentiation-like effects. This technique holds promise for clinical rehabilitation, y …
Studies of activity-dependent stimulation in non-human primates suggest that pairing each instance of volitional muscle activity with immedi …
Serum bilirubin and bilirubin/albumin ratio as predictors of bilirubin encephalopathy.
Iskander I, Gamaleldin R, El Houchi S, El Shenawy A, Seoud I, El Gharbawi N, Abou-Youssef H, Aravkin A, Wennberg RP. Iskander I, et al. Pediatrics. 2014 Nov;134(5):e1330-9. doi: 10.1542/peds.2013-1764. Epub 2014 Oct 20. Pediatrics. 2014. PMID: 25332491 Free PMC article.
The objective of the study was to identify thresholds and compare specificities of TSB and B/A in detecting patients with acute and posttreatment auditory and neurologic impairment. METHODS: A total of 193 term/near-term infants, admitted for severe jaundice to Cair …
The objective of the study was to identify thresholds and compare specificities of TSB and B/A in detecting patients with acute and posttrea …
Using CD4 percentage and age to optimize pediatric antiretroviral therapy initiation.
Yin DE, Warshaw MG, Miller WC, Castro H, Fiscus SA, Harper LM, Harrison LJ, Klein NJ, Lewis J, Melvin AJ, Tudor-Williams G, McKinney RE Jr; PENPACT-1 (PENTA 9/PACTG 390) Study Team. Yin DE, et al. Pediatrics. 2014 Oct;134(4):e1104-16. doi: 10.1542/peds.2014-0527. Pediatrics. 2014. PMID: 25266426 Free PMC article. Clinical Trial.
CONCLUSIONS: Initiating HAART at higher CD4% and younger ages maximizes potential for immunologic recovery. Guidelines should weigh immunologic benefits against long-term risks....
CONCLUSIONS: Initiating HAART at higher CD4% and younger ages maximizes potential for immunologic recovery. Guidelines should weigh immunolo …
Changes in proteinuria and albuminuria with initiation of antiretroviral therapy: data from a randomized trial comparing tenofovir disoproxil fumarate/emtricitabine versus abacavir/lamivudine.
Wyatt CM, Kitch D, Gupta SK, Tierney C, Daar ES, Sax PE, Ha B, Melbourne K, McComsey GA; AIDS Clinical Trials Group Study A5224s Team. Wyatt CM, et al. J Acquir Immune Defic Syndr. 2014 Sep 1;67(1):36-44. doi: 10.1097/QAI.0000000000000245. J Acquir Immune Defic Syndr. 2014. PMID: 25117929 Free PMC article. Clinical Trial.
These are the first data from a randomized trial to suggest that initiation of TDF/FTC may not be associated with the same degree of improvement in proteinuria and albuminuria that have been reported with other regimens. Future studies should consider the long-term clinica …
These are the first data from a randomized trial to suggest that initiation of TDF/FTC may not be associated with the same degree of improve …
Relative efficacy of mindfulness-based relapse prevention, standard relapse prevention, and treatment as usual for substance use disorders: a randomized clinical trial.
Bowen S, Witkiewitz K, Clifasefi SL, Grow J, Chawla N, Hsu SH, Carroll HA, Harrop E, Collins SE, Lustyk MK, Larimer ME. Bowen S, et al. JAMA Psychiatry. 2014 May;71(5):547-56. doi: 10.1001/jamapsychiatry.2013.4546. JAMA Psychiatry. 2014. PMID: 24647726 Free PMC article. Clinical Trial.
Mindfulness-based relapse prevention (MBRP), a group-based psychosocial aftercare, integrates evidence-based practices from mindfulness-based interventions and cognitive-behavioral relapse prevention (RP) approaches. OBJECTIVE: To evaluate the long-term efficacy of MBRP in …
Mindfulness-based relapse prevention (MBRP), a group-based psychosocial aftercare, integrates evidence-based practices from mindfulness-base …
52 results