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Year Number of Results
2008 3
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2010 7
2011 10
2012 13
2013 10
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2015 11
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2017 4
2018 2
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2022 3
2024 0

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66 results

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Page 1
A Phase 2 Randomized, Double-Blind, Placebo-controlled Trial of Oral Camostat Mesylate for Early Treatment of COVID-19 Outpatients Showed Shorter Illness Course and Attenuation of Loss of Smell and Taste.
Chupp G, Spichler-Moffarah A, Søgaard OS, Esserman D, Dziura J, Danzig L, Chaurasia R, Patra KP, Salovey A, Nunez A, May J, Astorino L, Patel A, Halene S, Wang J, Hui P, Patel P, Lu J, Li F, Gan G, Parziale S, Katsovich L, Desir GV, Vinetz JM. Chupp G, et al. medRxiv [Preprint]. 2022 Jan 31:2022.01.28.22270035. doi: 10.1101/2022.01.28.22270035. medRxiv. 2022. PMID: 35132421 Free PMC article. Preprint.
TRIAL REGISTRATION: Clinicaltrials.gov, NCT04353284 (04/20/20)(https://clinicaltrials.gov/ct2/show/NCT04353284?term=camostat+%2C+yale&draw=2&rank=1)....
TRIAL REGISTRATION: Clinicaltrials.gov, NCT04353284 (04/20/20)(https://clinicaltrials.gov/ct2/show/NCT04353284?term=camostat+%2C+yale …
Pioglitazone transiently stimulates paraoxonase-2 expression in male nonhuman primate brain: Implications for sex-specific therapeutics in neurodegenerative disorders.
Blackburn JK, Jamwal S, Wang W, Elsworth JD. Blackburn JK, et al. Neurochem Int. 2022 Jan;152:105222. doi: 10.1016/j.neuint.2021.105222. Epub 2021 Nov 9. Neurochem Int. 2022. PMID: 34767873 Free PMC article.
This transient increase was detected in substantia nigra, striatum, hippocampus, and dorsolateral prefrontal cortex The short-term impact of pioglitazone on PON2 expression in striatum may contribute to the discrepancy in the potency of the drug between short-term a …
This transient increase was detected in substantia nigra, striatum, hippocampus, and dorsolateral prefrontal cortex The short-term im …
Long-Term Complications in Youth-Onset Type 2 Diabetes.
TODAY Study Group; Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, Tesfaldet B, Tryggestad J, White NH, Zeitler P. TODAY Study Group, et al. N Engl J Med. 2021 Jul 29;385(5):416-426. doi: 10.1056/NEJMoa2100165. N Engl J Med. 2021. PMID: 34320286 Free PMC article.
Blood Biomarkers and 6- to 7-Year Childhood Outcomes Following Neonatal Encephalopathy.
Pappas A, Shankaran S, McDonald SA, Carlo WA, Laptook AR, Tyson JE, Das A, Skogstrand K, Hougaard DM, Higgins RD. Pappas A, et al. Am J Perinatol. 2022 May;39(7):732-749. doi: 10.1055/s-0040-1717072. Epub 2020 Oct 10. Am J Perinatol. 2022. PMID: 33038899 Free PMC article. Clinical Trial.
OBJECTIVE: This study aimed to profile the cytokine/chemokine response from day 0 to 7 in infants (36 weeks of gestational age) with neonatal encephalopathy (NE) and to explore the association with long-term outcomes. STUDY DESIGN: This was a secondary study of the Eunice …
OBJECTIVE: This study aimed to profile the cytokine/chemokine response from day 0 to 7 in infants (36 weeks of gestational age) with neonata …
Blood myo-inositol concentrations in preterm and term infants.
Brion LP, Phelps DL, Ward RM, Nolen TL, Hallman NMK, Das A, Zaccaro DJ, Ball MB, Watterberg KL, Frantz ID 3rd, Cotten CM, Poindexter BB, Oh W, Lugo RA, Van Meurs KP, O'Shea TM, Zaterka-Baxter KM, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Brion LP, et al. J Perinatol. 2021 Feb;41(2):247-254. doi: 10.1038/s41372-020-00799-5. Epub 2020 Sep 15. J Perinatol. 2021. PMID: 32934363 Free PMC article.
OBJECTIVE: To describe relationship between cord blood (representing fetal) myo-inositol concentrations and gestational age (GA) and to determine trends of blood concentrations in enterally and parenterally fed infants from birth to 70 days of age. DESIGN/METHODS: Samples …
OBJECTIVE: To describe relationship between cord blood (representing fetal) myo-inositol concentrations and gestational age (GA) and to dete …
Circadian-Like Rhythmicity of Extracellular Brain Glutamate in Epilepsy.
Sandhu MRS, Dhaher R, Gruenbaum SE, Raaisa R, Spencer DD, Pavlova MK, Zaveri HP, Eid T. Sandhu MRS, et al. Front Neurol. 2020 May 15;11:398. doi: 10.3389/fneur.2020.00398. eCollection 2020. Front Neurol. 2020. PMID: 32499751 Free PMC article.
We used a reverse translational rodent model of mesial temporal lobe epilepsy (MTLE) combined with long-term intracerebral microdialysis to monitor the hourly concentrations of glutamate in the seizure onset area (epileptogenic hippocampus) over several days. ...
We used a reverse translational rodent model of mesial temporal lobe epilepsy (MTLE) combined with long-term intracerebral microdialy …
Dose-Related Target Occupancy and Effects on Circuitry, Behavior, and Neuroplasticity of the Glycine Transporter-1 Inhibitor PF-03463275 in Healthy and Schizophrenia Subjects.
D'Souza DC, Carson RE, Driesen N, Johannesen J, Ranganathan M, Krystal JH; Yale GlyT1 Study Group. D'Souza DC, et al. Biol Psychiatry. 2018 Sep 15;84(6):413-421. doi: 10.1016/j.biopsych.2017.12.019. Epub 2018 Jan 31. Biol Psychiatry. 2018. PMID: 29499855 Free PMC article. Clinical Trial.
METHODS: In substudy 1, the effects of PF-03463275 (10, 20, and 40 mg twice a day) on occupancy of GlyT1 were tested using positron emission tomography and (18)F-MK-6577, and visual long-term potentiation (LTP) in schizophrenia patients (SZs) and healthy control subjects. …
METHODS: In substudy 1, the effects of PF-03463275 (10, 20, and 40 mg twice a day) on occupancy of GlyT1 were tested using positron emission …
Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study.
Gidding SS, Bacha F, Bjornstad P, Levitt Katz LE, Levitsky LL, Lynch J, Tryggestad JB, Weinstock RS, El Ghormli L, Lima JAC; TODAY Study Group. Gidding SS, et al. J Pediatr. 2018 Jan;192:86-92.e5. doi: 10.1016/j.jpeds.2017.09.012. J Pediatr. 2018. PMID: 29246363 Free PMC article. Clinical Trial.
CONCLUSIONS: Elevated serum concentrations of cardiac biomarkers were common in youth with type 2 diabetes, but their clinical significance is unclear and will require further long-term study. TRIAL REGISTRATION: ClinicalTrials.govNCT00081328....
CONCLUSIONS: Elevated serum concentrations of cardiac biomarkers were common in youth with type 2 diabetes, but their clinical significance …
Relationship of Kidney Injury Biomarkers with Long-Term Cardiovascular Outcomes after Cardiac Surgery.
Parikh CR, Puthumana J, Shlipak MG, Koyner JL, Thiessen-Philbrook H, McArthur E, Kerr K, Kavsak P, Whitlock RP, Garg AX, Coca SG. Parikh CR, et al. J Am Soc Nephrol. 2017 Dec;28(12):3699-3707. doi: 10.1681/ASN.2017010055. Epub 2017 Aug 14. J Am Soc Nephrol. 2017. PMID: 28808078 Free PMC article.
Clinical AKI, measured by serum creatinine elevation, is associated with long-term risks of adverse cardiovascular (CV) events and mortality in patients after cardiac surgery. ...These results suggest that clinical AKI at the time of cardiac surgery is indicative of concur …
Clinical AKI, measured by serum creatinine elevation, is associated with long-term risks of adverse cardiovascular (CV) events and mo …
66 results