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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2006 4
2007 1
2008 5
2009 9
2010 9
2011 5
2012 8
2013 7
2014 12
2015 13
2016 4
2017 4
2018 6
2019 5
2020 3
2021 6
2022 3
2023 5
2024 1

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92 results

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Page 1
Effect of carvedilol versus placebo on cardiac function in anthracycline-exposed survivors of childhood cancer (PREVENT-HF): a randomised, controlled, phase 2b trial.
Armenian SH, Hudson MM, Lindenfeld L, Chen S, Chow EJ, Colan S, Collier W, Su X, Marcus E, Echevarria M, Iukuridze A, Robison LL, Wong FL, Chen MH, Bhatia S. Armenian SH, et al. Lancet Oncol. 2024 Feb;25(2):235-245. doi: 10.1016/S1470-2045(23)00637-X. Epub 2024 Jan 9. Lancet Oncol. 2024. PMID: 38215764 Clinical Trial.
BACKGROUND: Carvedilol improves cardiac function in patients with heart failure but remains untested as cardioprotective therapy in long-term childhood cancer survivors (ie, those who have completed treatment for childhood cancer and are in remission) at risk for heart fai …
BACKGROUND: Carvedilol improves cardiac function in patients with heart failure but remains untested as cardioprotective therapy in long- …
Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors.
Leary SES, Onar-Thomas A, Fangusaro J, Gottardo NG, Cohen K, Smith A, Huang A, Haas-Kogan D, Fouladi M; COG Central Nervous System Committee. Leary SES, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30600. doi: 10.1002/pbc.30600. Epub 2023 Aug 3. Pediatr Blood Cancer. 2023. PMID: 37534382
There remain significant challenges to overcome: children with unresectable low-grade glioma may require multiple prolonged courses of therapy affecting quality of life; children with high-grade glioma have a dismal long-term prognosis; children with medulloblastoma may su …
There remain significant challenges to overcome: children with unresectable low-grade glioma may require multiple prolonged courses of thera …
Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials.
Raetz EA, Rebora P, Conter V, Schrappe M, Devidas M, Escherich G, Imai C, De Moerloose B, Schmiegelow K, Burns MA, Elitzur S, Pieters R, Attarbaschi A, Yeoh A, Pui CH, Stary J, Cario G, Bodmer N, Moorman AV, Buldini B, Vora A, Valsecchi MG. Raetz EA, et al. J Clin Oncol. 2023 Nov 10;41(32):5025-5034. doi: 10.1200/JCO.23.00088. Epub 2023 Jul 24. J Clin Oncol. 2023. PMID: 37487146
PURPOSE: Historically, patients with T-cell acute lymphoblastic leukemia (T-ALL) who fail to achieve remission at the end of induction (EOI) have had poor long-term survival. The goal of this study was to examine the efficacy of contemporary therapy, including allogeneic h …
PURPOSE: Historically, patients with T-cell acute lymphoblastic leukemia (T-ALL) who fail to achieve remission at the end of induction (EOI) …
Children's Oncology Group's 2023 blueprint for research: Radiation oncology.
Kalapurakal JA, Wolden SL, Haas-Kogan D, Laack NN, Hua CH, Paulino AC, Hill-Kayser CE, Hoppe BS, Fitzgerald TJ; COG Radiation Oncology Discipline Committee. Kalapurakal JA, et al. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30593. doi: 10.1002/pbc.30593. Epub 2023 Jul 24. Pediatr Blood Cancer. 2023. PMID: 37486145
Phase II Randomized Trial of Lenalidomide in Children With Pilocytic Astrocytomas and Optic Pathway Gliomas: A Report From the Children's Oncology Group.
Warren KE, Vezina G, Krailo M, Springer L, Buxton A, Peer CJ, Figg WD, William-Hughes C, Kessel S, Fouladi M, Gajjar A, Bowers D. Warren KE, et al. J Clin Oncol. 2023 Jun 20;41(18):3374-3383. doi: 10.1200/JCO.22.01777. Epub 2023 May 1. J Clin Oncol. 2023. PMID: 37126770 Clinical Trial.
PURPOSE: Children with low-grade glioma often require long-term therapy and suffer from treatment morbidity. Although targeted agents are promising, tumor targets often encompass normal developmental pathways and long-term effects of inhibition are unknown. ...
PURPOSE: Children with low-grade glioma often require long-term therapy and suffer from treatment morbidity. Although targeted agents …
Dexrazoxane and Long-Term Heart Function in Survivors of Childhood Cancer.
Chow EJ, Aggarwal S, Doody DR, Aplenc R, Armenian SH, Baker KS, Bhatia S, Blythe N, Colan SD, Constine LS, Freyer DR, Kopp LM, Laverdière C, Leisenring WM, Sasaki N, Vrooman LM, Asselin BL, Schwartz CL, Lipshultz SE. Chow EJ, et al. J Clin Oncol. 2023 Apr 20;41(12):2248-2257. doi: 10.1200/JCO.22.02423. Epub 2023 Jan 20. J Clin Oncol. 2023. PMID: 36669148 Free PMC article.
PURPOSE: For survivors of childhood cancer treated with doxorubicin, dexrazoxane is cardioprotective for at least 5 years. However, longer-term data are lacking. METHODS: Within the Children's Oncology Group and the Dana Farber Cancer Institute's Childhood Acute Lymphoblas …
PURPOSE: For survivors of childhood cancer treated with doxorubicin, dexrazoxane is cardioprotective for at least 5 years. However, longer- …
Randomized Clinical Trial of a Self-care and Communication Intervention for Parents of Adolescent/Young Adults Undergoing High-Risk Cancer Treatment: A Report From the Children's Oncology Group.
Haase JE, Stegenga K, Robb SL, Hooke MC, Burns DS, Monahan PO, Stump TE, Henley AK, Haut PR, Cherven B, Roll L, Langevin AM, Pickler RH, Albritton K, Hawkins D, Osterkamp E, Mitby P, Smith J, Diaz VR, Garcia-Frausto E, Moore M. Haase JE, et al. Cancer Nurs. 2022 Jul-Aug 01;45(4):316-331. doi: 10.1097/NCC.0000000000001038. Epub 2021 Nov 24. Cancer Nurs. 2022. PMID: 34817419 Free PMC article. Clinical Trial.
Qualitative data demonstrate the parent intervention raised self-awareness and parent confidence in the short term. CONCLUSION: Parents found their intervention helpful. Absence of significant results may be due to short intervention duration, need for tailored content, un …
Qualitative data demonstrate the parent intervention raised self-awareness and parent confidence in the short term. CONCLUSION: Paren …
A gene expression-based model predicts outcome in children with intermediate-risk classical Hodgkin lymphoma.
Johnston RL, Mottok A, Chan FC, Jiang A, Diepstra A, Visser L, Telenius A, Gascoyne RD, Friedman DL, Schwartz CL, Kelly KM, Scott DW, Horton TM, Steidl C. Johnston RL, et al. Blood. 2022 Feb 10;139(6):889-893. doi: 10.1182/blood.2021011941. Blood. 2022. PMID: 34662378 Free PMC article. Clinical Trial.
Although cHL is highly curable, treatment with chemotherapy and radiation often come at the cost of long-term toxicity and morbidity. Effective risk-stratification tools are needed to tailor therapy. ...
Although cHL is highly curable, treatment with chemotherapy and radiation often come at the cost of long-term toxicity and morbidity. …
Late health outcomes after dexrazoxane treatment: A report from the Children's Oncology Group.
Chow EJ, Aplenc R, Vrooman LM, Doody DR, Huang YV, Aggarwal S, Armenian SH, Baker KS, Bhatia S, Constine LS, Freyer DR, Kopp LM, Leisenring WM, Asselin BL, Schwartz CL, Lipshultz SE. Chow EJ, et al. Cancer. 2022 Feb 15;128(4):788-796. doi: 10.1002/cncr.33974. Epub 2021 Oct 13. Cancer. 2022. PMID: 34644414 Free PMC article. Clinical Trial.
BACKGROUND: The objective of this study was to examine long-term outcomes among children newly diagnosed with cancer who were treated in dexrazoxane-containing clinical trials. ...CONCLUSIONS: Dexrazoxane did not appear to adversely affect long-term mortality, event …
BACKGROUND: The objective of this study was to examine long-term outcomes among children newly diagnosed with cancer who were treated …
Impact of the First Generation of Children's Oncology Group Clinical Trials on Clinical Practice for Wilms Tumor.
Dome JS, Mullen EA, Dix DB, Gratias EJ, Ehrlich PF, Daw NC, Geller JI, Chintagumpala M, Khanna G, Kalapurakal JA, Renfro LA, Perlman EJ, Grundy PE, Fernandez CV. Dome JS, et al. J Natl Compr Canc Netw. 2021 Aug 1;19(8):978-985. doi: 10.6004/jnccn.2021.7070. J Natl Compr Canc Netw. 2021. PMID: 34416705 Free PMC article. Review.
Conversely, therapy was reduced for patient subgroups with good outcomes and potential for long-term toxicity, such as those with lung metastasis with complete lung nodule response after 6 weeks of chemotherapy. ...
Conversely, therapy was reduced for patient subgroups with good outcomes and potential for long-term toxicity, such as those with lun …
92 results