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Late Effects Screening Guidelines after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement From the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects After Pediatric HCT.
Dietz AC, Savage SA, Vlachos A, Mehta PA, Bresters D, Tolar J, Bonfim C, Dalle JH, de la Fuente J, Skinner R, Boulad F, Duncan CN, Baker KS, Pulsipher MA, Lipton JM, Wagner JE, Alter BP. Dietz AC, et al. Biol Blood Marrow Transplant. 2017 Sep;23(9):1422-1428. doi: 10.1016/j.bbmt.2017.05.022. Epub 2017 May 19. Biol Blood Marrow Transplant. 2017. PMID: 28533057 Free PMC article. Review.
This companion article outlines consensus disease-specific long-term follow-up screening guidelines for patients with IMBFS....
This companion article outlines consensus disease-specific long-term follow-up screening guidelines for patients with IMBFS....
Recommendations for Screening and Management of Late Effects in Patients with Severe Combined Immunodeficiency after Allogenic Hematopoietic Cell Transplantation: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT.
Heimall J, Buckley RH, Puck J, Fleisher TA, Gennery AR, Haddad E, Neven B, Slatter M, Roderick S, Baker KS, Dietz AC, Duncan C, Griffith LM, Notarangelo L, Pulsipher MA, Cowan MJ. Heimall J, et al. Biol Blood Marrow Transplant. 2017 Aug;23(8):1229-1240. doi: 10.1016/j.bbmt.2017.04.026. Epub 2017 May 4. Biol Blood Marrow Transplant. 2017. PMID: 28479164 Free PMC article. Review.
Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Cell Transplantation for Inherited Bone Marrow Failure Syndromes: Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation.
Dietz AC, Mehta PA, Vlachos A, Savage SA, Bresters D, Tolar J, Boulad F, Dalle JH, Bonfim C, de la Fuente J, Duncan CN, Baker KS, Pulsipher MA, Lipton JM, Wagner JE, Alter BP. Dietz AC, et al. Biol Blood Marrow Transplant. 2017 May;23(5):726-735. doi: 10.1016/j.bbmt.2017.01.075. Epub 2017 Jan 20. Biol Blood Marrow Transplant. 2017. PMID: 28115275 Free PMC article. Review.
Later in life, these patients face a variety of medical conditions, which may be a manifestation of underlying disease or due to pre-HCT therapy, the HCT, or a combination of all these elements. Very limited long-term follow-up data exist in these populations, with FA the …
Later in life, these patients face a variety of medical conditions, which may be a manifestation of underlying disease or due to pre-HCT the …
Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Stem Cell Transplantation (HCT) for Severe Combined Immunodeficiency Patients: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT.
Heimall J, Puck J, Buckley R, Fleisher TA, Gennery AR, Neven B, Slatter M, Haddad E, Notarangelo LD, Baker KS, Dietz AC, Duncan C, Pulsipher MA, Cowan MJ. Heimall J, et al. Biol Blood Marrow Transplant. 2017 Mar;23(3):379-387. doi: 10.1016/j.bbmt.2016.12.619. Epub 2017 Jan 6. Biol Blood Marrow Transplant. 2017. PMID: 28068510 Free PMC article. Review.
In at least 1 study of SCID patients who received no conditioning, long-term survival was 77% at 8.7 years (range out to 26 years) after transplantation. ...Specific guidelines regarding a recommended approach to long-term follow-up, including laboratory and clinica …
In at least 1 study of SCID patients who received no conditioning, long-term survival was 77% at 8.7 years (range out to 26 years) af …
The Second Pediatric Blood and Marrow Transplant Consortium International Consensus Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: Defining the Unique Late Effects of Children Undergoing Hematopoietic Cell Transplantation for Immune Deficiencies, Inherited Marrow Failure Disorders, and Hemoglobinopathies.
Dietz AC, Duncan CN, Alter BP, Bresters D, Cowan MJ, Notarangelo L, Rosenberg PS, Shenoy S, Skinner R, Walters MC, Wagner J, Baker KS, Pulsipher MA. Dietz AC, et al. Biol Blood Marrow Transplant. 2017 Jan;23(1):24-29. doi: 10.1016/j.bbmt.2016.10.004. Epub 2016 Oct 11. Biol Blood Marrow Transplant. 2017. PMID: 27737772 Free PMC article. Review.
The purpose of the conference was to address the unmet need for greater understanding of and the screening for long-term complications in the growing population of survivors of transplantation for nonmalignant disorders. ...
The purpose of the conference was to address the unmet need for greater understanding of and the screening for long-term complication …
Evolving hematopoietic stem cell transplantation strategies in severe aplastic anemia.
Dietz AC, Lucchini G, Samarasinghe S, Pulsipher MA. Dietz AC, et al. Curr Opin Pediatr. 2016 Feb;28(1):3-11. doi: 10.1097/MOP.0000000000000299. Curr Opin Pediatr. 2016. PMID: 26626557 Free PMC article. Review.
RECENT FINDINGS: Advances in understanding the genetics of inherited bone marrow failure syndromes (IBMFS) have allowed more confidence in accurately diagnosing SAA and avoiding treatments that could be dangerous and ineffective in individuals with IBMFS, which can be diagnosed i …
RECENT FINDINGS: Advances in understanding the genetics of inherited bone marrow failure syndromes (IBMFS) have allowed more confidence in a …
National Cancer Institute, National Heart, Lung and Blood Institute/Pediatric Blood and Marrow Transplantation Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: the need for pediatric-specific long-term follow-up guidelines.
Pulsipher MA, Skinner R, McDonald GB, Hingorani S, Armenian SH, Cooke KR, Gracia C, Petryk A, Bhatia S, Bunin N, Nieder ML, Dvorak CC, Sung L, Sanders JE, Kurtzberg J, Baker KS. Pulsipher MA, et al. Biol Blood Marrow Transplant. 2012 Mar;18(3):334-47. doi: 10.1016/j.bbmt.2012.01.003. Epub 2012 Jan 14. Biol Blood Marrow Transplant. 2012. PMID: 22248713 Free PMC article.
In this article we discuss the strengths and weaknesses of current published recommendations and conclude that pediatric-specific guidelines for post-HCT screening and management would be beneficial to the long-term health of these patients and would promote late effects r …
In this article we discuss the strengths and weaknesses of current published recommendations and conclude that pediatric-specific guidelines …
NCI, NHLBI/PBMTC First International Conference on Late Effects after Pediatric Hematopoietic Cell Transplantation: health-related quality of life, functional, and neurocognitive outcomes.
Parsons SK, Phipps S, Sung L, Baker KS, Pulsipher MA, Ness KK. Parsons SK, et al. Biol Blood Marrow Transplant. 2012 Feb;18(2):162-71. doi: 10.1016/j.bbmt.2011.12.501. Epub 2011 Dec 10. Biol Blood Marrow Transplant. 2012. PMID: 22155139 Free PMC article.
Direct and comprehensive measures of physical performance may help further clarify the proportion of individuals who have subclinical problems amenable to intervention before apparent functional loss becomes a problem. There is a need to include longer term survivors in su …
Direct and comprehensive measures of physical performance may help further clarify the proportion of individuals who have subclinical proble …
National Cancer Institute-National Heart, Lung and Blood Institute/pediatric Blood and Marrow Transplant Consortium First International Consensus Conference on late effects after pediatric hematopoietic cell transplantation: long-term organ damage and dysfunction.
Nieder ML, McDonald GB, Kida A, Hingorani S, Armenian SH, Cooke KR, Pulsipher MA, Baker KS. Nieder ML, et al. Biol Blood Marrow Transplant. 2011 Nov;17(11):1573-84. doi: 10.1016/j.bbmt.2011.09.013. Epub 2011 Oct 1. Biol Blood Marrow Transplant. 2011. PMID: 21963877 Free PMC article.
Long-term complications after hematopoietic cell transplantation (HCT) have been studied in detail. ...The interplay between inflammatory processes and dysregulated cellular repair likely contributes to end-organ fibrosis and dysfunction. Although many long-term pro …
Long-term complications after hematopoietic cell transplantation (HCT) have been studied in detail. ...The interplay between inflamma …
NCI, NHLBI first international consensus conference on late effects after pediatric hematopoietic cell transplantation: etiology and pathogenesis of late effects after HCT performed in childhood--methodologic challenges.
Bhatia S, Davies SM, Scott Baker K, Pulsipher MA, Hansen JA. Bhatia S, et al. Biol Blood Marrow Transplant. 2011 Oct;17(10):1428-35. doi: 10.1016/j.bbmt.2011.07.005. Epub 2011 Jul 18. Biol Blood Marrow Transplant. 2011. PMID: 21763253 Free PMC article. Review.
Technical and supportive care has resulted in survival rates that exceed 70% for those who survive the first 2 years after HCT. However, long-term survivors carry a high burden of morbidity, including endocrinopathies, musculoskeletal disorders, cardiopulmonary compromise, …
Technical and supportive care has resulted in survival rates that exceed 70% for those who survive the first 2 years after HCT. However, lon …