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Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway.
Rose K, Ouellette Y, Bolon M, Tyml K. Rose K, et al. Among authors: tyml k. J Cell Physiol. 2005 Jul;204(1):131-8. doi: 10.1002/jcp.20283. J Cell Physiol. 2005. PMID: 15672421
The aim of the present study was to examine the effect of a short-term hypoxia (0.1% O(2), 1 h) plus reoxygenation (H/R) on electrical coupling in cultured monolayers of microvascular endothelial cells (rat skeletal muscle origin). ...These results indicate that endothelia …
The aim of the present study was to examine the effect of a short-term hypoxia (0.1% O(2), 1 h) plus reoxygenation (H/R) on electrica …
Nitric oxide attenuates but superoxide enhances iNOS expression in endotoxin- and IFNgamma-stimulated skeletal muscle endothelial cells.
Wu F, Cepinskas G, Wilson JX, Tyml K. Wu F, et al. Among authors: tyml k. Microcirculation. 2001 Dec;8(6):415-25. doi: 10.1038/sj/mn/7800113. Microcirculation. 2001. PMID: 11781814
METHODS: To model sepsis in vitro, monolayers of microvascular ECs derived from rat skeletal muscle were incubated with a mixture of lipopolysaccharide (LPS) (25 ng/mL) and interferongamma (IFNgamma) (100 U/mL) for up to 24 hours. Next, a long-term release NO donor (DETA N …
METHODS: To model sepsis in vitro, monolayers of microvascular ECs derived from rat skeletal muscle were incubated with a mixture of lipopol …
Capillary ultrastructure and functional capillary density.
Mathieu-Costello O, Manciet LH, Tyml K. Mathieu-Costello O, et al. Among authors: tyml k. Int J Microcirc Clin Exp. 1995 Sep-Oct;15(5):231-7. doi: 10.1159/000179023. Int J Microcirc Clin Exp. 1995. PMID: 8852620
It suggested an effect of the degree of tissue deterioration on the hyperemic response after short-term disuse in rat muscle, compared to longer-term atrophy in frog. ...
It suggested an effect of the degree of tissue deterioration on the hyperemic response after short-term disuse in rat muscle, compare …
Microvascular response to ischemia, and endothelial ultrastructure, in disused skeletal muscle.
Tyml K, Mathieu-Costello O, Noble E. Tyml K, et al. Microvasc Res. 1995 Jan;49(1):17-32. doi: 10.1006/mvre.1995.1003. Microvasc Res. 1995. PMID: 7746162
TTX disuse did not alter the pattern of reactive hyperemia following 30 min of complete ischemia. These results suggest that short-term TTX-induced atrophy affects both microvascular structure and resting state blood flow in rat skeletal muscle, but it does not affect the …
TTX disuse did not alter the pattern of reactive hyperemia following 30 min of complete ischemia. These results suggest that short-term …
Distribution of red blood cell velocity in capillary network, and endothelial ultrastructure, in aged rat skeletal muscle.
Tyml K, Mathieu-Costello O, Budreau CH. Tyml K, et al. Microvasc Res. 1992 Jul;44(1):1-13. doi: 10.1016/0026-2862(92)90097-9. Microvasc Res. 1992. PMID: 1640874
Within the microvascular bed, there was a less uniform postischemic response among capillaries. No long-term effect of ischemia was seen as velocity was already stable at the preischemic level 20 min after the tourniquet release. ...Thus, in this muscle model, aging was as …
Within the microvascular bed, there was a less uniform postischemic response among capillaries. No long-term effect of ischemia was s …