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Long-term outcome of patients presenting with myocardial injury or myocardial infarction.
Haller PM, Kellner C, Sörensen NA, Lehmacher J, Toprak B, Schock A, Hartikainen TS, Twerenbold R, Zeller T, Westermann D, Neumann JT. Haller PM, et al. Among authors: twerenbold r. Clin Res Cardiol. 2023 Nov 20. doi: 10.1007/s00392-023-02334-w. Online ahead of print. Clin Res Cardiol. 2023. PMID: 37982865
AIMS: Patients with acute or chronic myocardial injury are frequently identified in the context of suspected myocardial infarction (MI). We aimed to investigate their long-term follow-up. METHODS AND RESULTS: We prospectively enrolled 2714 patients with suspected MI and fo …
AIMS: Patients with acute or chronic myocardial injury are frequently identified in the context of suspected myocardial infarction (MI). We …
Diagnostic and prognostic value of the sex-specific 99th percentile of four high-sensitivity cardiac troponin assays in patients with suspected myocardial infarction.
Lehmacher J, Sörensen NA, Twerenbold R, Goßling A, Haller PM, Hartikainen TS, Schock A, Toprak B, Zeller T, Westermann D, Neumann JT. Lehmacher J, et al. Among authors: twerenbold r. Eur Heart J Acute Cardiovasc Care. 2024 Feb 9;13(1):3-12. doi: 10.1093/ehjacc/zuad131. Eur Heart J Acute Cardiovasc Care. 2024. PMID: 37890108

Concentrations above 99th percentile were independent predictors for impaired long-term outcome (hazard ratios 1.2-1.5, P < 0.001). CONCLUSION: We describe a good diagnostic accuracy of four hs-cTn assays using the assay-specific 99th percentile for detection of MI. ...

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Concentrations above 99th percentile were independent predictors for impaired long-term outcome (hazard ratios 1.2-1.5, P < 0.001)

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Transcatheter aortic valve implantation versus surgical aortic valve replacement in patients at low to intermediate surgical risk: rationale and design of the randomised DEDICATE Trial.
Seiffert M, Vonthein R, Baumgartner H, Borger MA, Choi YH, Falk V, Frey N, Hagendorff A, Hagl C, Hamm C, König IR, Landmesser U, Massberg S, Reichenspurner H, Thiele H, Twerenbold R, Vens M, Walther T, Ziegler A, Cremer J, Blankenberg S. Seiffert M, et al. Among authors: twerenbold r. EuroIntervention. 2023 Oct 23;19(8):652-658. doi: 10.4244/EIJ-D-23-00232. EuroIntervention. 2023. PMID: 37655862 Free article.
However, in younger, low-risk patients for whom both therapeutic options, TAVI and SAVR, are applicable, the optimal treatment strategy remains controversial, as data on long-term outcomes remain limited. The DEDICATE-DZHK6 Trial is an investigator-initiated, industry-inde …
However, in younger, low-risk patients for whom both therapeutic options, TAVI and SAVR, are applicable, the optimal treatment strategy rema …
Similar 5-Year Survival in Transfemoral and Transapical TAVI Patients: A Single-Center Experience.
Mork C, Twerenbold R, Gahl B, Eckstein F, Jeger R, Kaiser C, Reuthebuch O. Mork C, et al. Among authors: twerenbold r. Bioengineering (Basel). 2023 Jan 24;10(2):156. doi: 10.3390/bioengineering10020156. Bioengineering (Basel). 2023. PMID: 36829650 Free PMC article.
We aimed to compare different patient risk profiles, access-related complications, and long-term survival using inverse probability treatment weighting. This is a retrospective, single-center analysis of 925 consecutive patients with aortic valve stenosis undergoing TF-TAV …
We aimed to compare different patient risk profiles, access-related complications, and long-term survival using inverse probability t …
Development and validation of a prognostic model for the early identification of COVID-19 patients at risk of developing common long COVID symptoms.
Deforth M, Gebhard CE, Bengs S, Buehler PK, Schuepbach RA, Zinkernagel AS, Brugger SD, Acevedo CT, Patriki D, Wiggli B, Twerenbold R, Kuster GM, Pargger H, Schefold JC, Spinetti T, Wendel-Garcia PD, Hofmaenner DA, Gysi B, Siegemund M, Heinze G, Regitz-Zagrosek V, Gebhard C, Held U. Deforth M, et al. Among authors: twerenbold r. Diagn Progn Res. 2022 Nov 17;6(1):22. doi: 10.1186/s41512-022-00135-9. Diagn Progn Res. 2022. PMID: 36384641 Free PMC article.
Included were adult patients diagnosed with COVID-19 between February and December 2020 and treated as outpatients, at ward or intensive/intermediate care unit. Perceived long-term health impairments, including reduced exercise tolerance/reduced resilience, shortness of br …
Included were adult patients diagnosed with COVID-19 between February and December 2020 and treated as outpatients, at ward or intensive/int …
Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective cohort study (COVI-GAPP).
Risch M, Grossmann K, Aeschbacher S, Weideli OC, Kovac M, Pereira F, Wohlwend N, Risch C, Hillmann D, Lung T, Renz H, Twerenbold R, Rothenbühler M, Leibovitz D, Kovacevic V, Markovic A, Klaver P, Brakenhoff TB, Franks B, Mitratza M, Downward GS, Dowling A, Montes S, Grobbee DE, Cronin M, Conen D, Goodale BM, Risch L; COVID-19 remote early detection (COVID-RED) consortium. Risch M, et al. Among authors: twerenbold r. BMJ Open. 2022 Jun 21;12(6):e058274. doi: 10.1136/bmjopen-2021-058274. BMJ Open. 2022. PMID: 35728900 Free PMC article. Clinical Trial.
Based on a random split, the test set included 30% of participants and 70% were selected for the training set. The developed long short-term memory (LSTM) based recurrent neural network (RNN) algorithm had a recall (sensitivity) of 0.73 in the training set and 0.68 in the …
Based on a random split, the test set included 30% of participants and 70% were selected for the training set. The developed long short-t …
Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme.
Petersen EL, Goßling A, Adam G, Aepfelbacher M, Behrendt CA, Cavus E, Cheng B, Fischer N, Gallinat J, Kühn S, Gerloff C, Koch-Gromus U, Härter M, Hanning U, Huber TB, Kluge S, Knobloch JK, Kuta P, Schmidt-Lauber C, Lütgehetmann M, Magnussen C, Mayer C, Muellerleile K, Münch J, Nägele FL, Petersen M, Renné T, Riedl KA, Rimmele DL, Schäfer I, Schulz H, Tahir E, Waschki B, Wenzel JP, Zeller T, Ziegler A, Thomalla G, Twerenbold R, Blankenberg S. Petersen EL, et al. Among authors: twerenbold r. Eur Heart J. 2022 Mar 14;43(11):1124-1137. doi: 10.1093/eurheartj/ehab914. Eur Heart J. 2022. PMID: 34999762 Free PMC article.
AIMS: Long-term sequelae may occur after SARS-CoV-2 infection. We comprehensively assessed organ-specific functions in individuals after mild to moderate SARS-CoV-2 infection compared with controls from the general population. ...
AIMS: Long-term sequelae may occur after SARS-CoV-2 infection. We comprehensively assessed organ-specific functions in individuals af …
Incidence, clinical presentation, management, and outcome of acute pericarditis and myopericarditis.
Prepoudis A, Koechlin L, Nestelberger T, Boeddinghaus J, Lopez-Ayala P, Wussler D, Zimmermann T, Rubini Giménez M, Strebel I, Puelacher C, Shrestha S, Keller DI, Christ M, Gualandro DM, Twerenbold R, Martinez-Nadal G, Lopez-Barbeito B, Miro O, Mueller C; APACE investigators. Prepoudis A, et al. Among authors: twerenbold r. Eur Heart J Acute Cardiovasc Care. 2022 Feb 8;11(2):137-147. doi: 10.1093/ehjacc/zuab108. Eur Heart J Acute Cardiovasc Care. 2022. PMID: 34849666 Clinical Trial.
The overall incidence of pericarditis and myopericarditis was estimated relative to the established incidence of NSTEMI. Current management and long-term outcome of both conditions were also assessed. Among 2533 chest pain patients, the incidence of pericarditis, myoperica …
The overall incidence of pericarditis and myopericarditis was estimated relative to the established incidence of NSTEMI. Current management …
"Ciprofloxacin-induced" bilateral quadriceps tendon rupture: A case report and conclusions of the recent literature.
Suter C, Leemann H, Twerenbold R. Suter C, et al. Among authors: twerenbold r. Trauma Case Rep. 2021 Feb 10;32:100423. doi: 10.1016/j.tcr.2021.100423. eCollection 2021 Apr. Trauma Case Rep. 2021. PMID: 33665316 Free PMC article.
This review, published in early 2019, led to restriction of the usage of fluoroquinolones due to the risk of disabling and potentially long-term side effects. Furthermore, there have been a number of meta-analyses published in the recent years, which brought more clarity t …
This review, published in early 2019, led to restriction of the usage of fluoroquinolones due to the risk of disabling and potentially long- …
Serum Neurofilament Light Chain Levels in the Intensive Care Unit: Comparison between Severely Ill Patients with and without Coronavirus Disease 2019.
Sutter R, Hert L, De Marchis GM, Twerenbold R, Kappos L, Naegelin Y, Kuster GM, Benkert P, Jost J, Maceski AM, Rüegg S, Siegemund M, Leppert D, Tschudin-Sutter S, Kuhle J. Sutter R, et al. Among authors: twerenbold r. Ann Neurol. 2021 Mar;89(3):610-616. doi: 10.1002/ana.26004. Epub 2021 Jan 11. Ann Neurol. 2021. PMID: 33377539
After adjusting for neurological comorbidities and age, sNfL concentrations were higher in patients with COVID-19 versus both comparator groups. Higher sNfL levels were associated with unfavorable short-term outcome, indicating that neuronal injury is common and pronounced …
After adjusting for neurological comorbidities and age, sNfL concentrations were higher in patients with COVID-19 versus both comparator gro …
48 results