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High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens.
Microbiol Spectr. 2022 Feb 23;10(1):e0169521. doi: 10.1128/spectrum.01695-21. Epub 2022 Feb 16.
Microbiol Spectr. 2022.
PMID: 35171046
Free PMC article.
Global control of COVID-19 will require the deployment of vaccines capable of inducing long-term protective immunity against SARS-CoV-2 variants. In this report, we describe an adjuvanted subunit candidate vaccine that affords elevated, sustained, and cross-variant SARS-Co …
Global control of COVID-19 will require the deployment of vaccines capable of inducing long-term protective immunity against SARS-CoV …
The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells.
Duette G, Hiener B, Morgan H, Mazur FG, Mathivanan V, Horsburgh BA, Fisher K, Tong O, Lee E, Ahn H, Shaik A, Fromentin R, Hoh R, Bacchus-Souffan C, Nasr N, Cunningham AL, Hunt PW, Chomont N, Turville SG, Deeks SG, Kelleher AD, Schlub TE, Palmer S.
Duette G, et al. Among authors: turville sg.
J Clin Invest. 2022 Apr 1;132(7):e154422. doi: 10.1172/JCI154422.
J Clin Invest. 2022.
PMID: 35133986
Free PMC article.
Despite long-term antiretroviral therapy (ART), HIV-1 persists within a reservoir of CD4+ T cells that contribute to viral rebound if treatment is interrupted. ...
Despite long-term antiretroviral therapy (ART), HIV-1 persists within a reservoir of CD4+ T cells that contribute to viral rebound if …
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Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells.
Turville SG, Santos JJ, Frank I, Cameron PU, Wilkinson J, Miranda-Saksena M, Dable J, Stössel H, Romani N, Piatak M Jr, Lifson JD, Pope M, Cunningham AL.
Turville SG, et al.
Blood. 2004 Mar 15;103(6):2170-9. doi: 10.1182/blood-2003-09-3129. Epub 2003 Nov 20.
Blood. 2004.
PMID: 14630806
Free article.
Although viral harboring and transfer from nonlysosomal compartments was transient, given DC-associated virus protein, nucleic acids, and infectious HIV-1 transfer to CD4+, lymphocytes decayed within 24 hours. However a second long-term transfer phase was apparent in immat …
Although viral harboring and transfer from nonlysosomal compartments was transient, given DC-associated virus protein, nucleic acids, and in …
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