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Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines.
Zsigrai S, Kalmár A, Barták BK, Nagy ZB, Szigeti KA, Valcz G, Kothalawala W, Dankó T, Sebestyén A, Barna G, Pipek O, Csabai I, Tulassay Z, Igaz P, Takács I, Molnár B. Zsigrai S, et al. Among authors: tulassay z. Cancers (Basel). 2022 Apr 3;14(7):1820. doi: 10.3390/cancers14071820. Cancers (Basel). 2022. PMID: 35406592 Free PMC article.
FA is involved in genetic and epigenetic regulation; therefore, it has a dual modulatory role in established neoplasms. We aimed to investigate the effect of short-term (72 h) FA supplementation on colorectal cancer; hence, HT-29 and SW480 cells were exposed to different F …
FA is involved in genetic and epigenetic regulation; therefore, it has a dual modulatory role in established neoplasms. We aimed to investig …
Pharmacological Approach to Gastric Acid Suppression: Past, Present, and Future.
Herszényi L, Bakucz T, Barabás L, Tulassay Z. Herszényi L, et al. Among authors: tulassay z. Dig Dis. 2020;38(2):104-111. doi: 10.1159/000505204. Epub 2019 Dec 17. Dig Dis. 2020. PMID: 31846972 Free article. Review.
The major advance has been the development of acid pump -antagonists, the potassium channel acid blocking drugs (-P-CABs). Long-term studies comparing P-CABs with PPIs will help to define the exact place and safety profile of this class of drug in the management of acid-re …
The major advance has been the development of acid pump -antagonists, the potassium channel acid blocking drugs (-P-CABs). Long-term …
Ferric maltol therapy for iron deficiency anaemia in patients with inflammatory bowel disease: long-term extension data from a Phase 3 study.
Schmidt C, Ahmad T, Tulassay Z, Baumgart DC, Bokemeyer B, Howaldt S, Stallmach A, Büning C; AEGIS Study Group. Schmidt C, et al. Among authors: tulassay z. Aliment Pharmacol Ther. 2016 Aug;44(3):259-70. doi: 10.1111/apt.13665. Epub 2016 May 29. Aliment Pharmacol Ther. 2016. PMID: 27237709 Free PMC article. Clinical Trial.
BACKGROUND: Ferric maltol was effective and well-tolerated in iron deficiency anaemia patients with inflammatory bowel disease during a 12-week placebo-controlled trial. AIM: To perform a Phase 3 extension study evaluating long-term efficacy and safety with ferric maltol i …
BACKGROUND: Ferric maltol was effective and well-tolerated in iron deficiency anaemia patients with inflammatory bowel disease during a 12-w …
Bisulfite-Based DNA Methylation Analysis from Recent and Archived Formalin-Fixed, Paraffin Embedded Colorectal Tissue Samples.
Kalmár A, Péterfia B, Hollósi P, Wichmann B, Bodor A, Patai ÁV, Schöller A, Krenács T, Tulassay Z, Molnár B. Kalmár A, et al. Among authors: tulassay z. Pathol Oncol Res. 2015 Sep;21(4):1149-56. doi: 10.1007/s12253-015-9945-4. Epub 2015 May 20. Pathol Oncol Res. 2015. PMID: 25991403 Free article.
In conclusion, reproducible DNA methylation patterns were obtained from recent samples using both isolation kits. However, long term storage may affect the reliability of the results leading to moderate differences between the efficiency of isolation kits....
In conclusion, reproducible DNA methylation patterns were obtained from recent samples using both isolation kits. However, long term …
Colorectal cancer in patients with inflammatory bowel disease: the true impact of the risk.
Herszényi L, Barabás L, Miheller P, Tulassay Z. Herszényi L, et al. Among authors: tulassay z. Dig Dis. 2015;33(1):52-7. doi: 10.1159/000368447. Epub 2014 Dec 17. Dig Dis. 2015. PMID: 25531497 Review.
IBD-associated CRC can frequently be detected at late stages and at a younger age. The long-term prognosis of CRC may be poorer in patients with IBD than in those with sporadic CRC. ...
IBD-associated CRC can frequently be detected at late stages and at a younger age. The long-term prognosis of CRC may be poorer in pa …
Helicobacter pylori infection: new pathogenetic and clinical aspects.
Hagymási K, Tulassay Z. Hagymási K, et al. Among authors: tulassay z. World J Gastroenterol. 2014 Jun 7;20(21):6386-99. doi: 10.3748/wjg.v20.i21.6386. World J Gastroenterol. 2014. PMID: 24914360 Free PMC article. Review.
On the other hand, there is data showing that H. pylori infection could be beneficial for some human diseases. The unpredictability of the long-term consequences of H. pylori infection and the economic challenge in eradicating it is why identification of high-risk individu …
On the other hand, there is data showing that H. pylori infection could be beneficial for some human diseases. The unpredictability of the l …
[Statins and gastrointestinal cancers].
Sági V, Herszényi L, Tulassay Z, Gasztonyi B. Sági V, et al. Among authors: tulassay z. Orv Hetil. 2014 May 4;155(18):687-93. doi: 10.1556/OH.2014.29901. Orv Hetil. 2014. PMID: 24776382 Review. Hungarian.
Chemopreventive effect of hydrophilic statins could not be detected but it seems to be significant in the case of hydrophobic statins. There are only few data available on the long-term daily use of 30-40 mg statins. Further long-term evaluation of the effect of sta …
Chemopreventive effect of hydrophilic statins could not be detected but it seems to be significant in the case of hydrophobic statins. There …
[Prevalence of gastric polypoid lesions at an endoscopic facility].
Csontos AA, Fekete B, Lőrinczy K, Terjék O, Berczi L, Juhász M, Miheller P, Tulassay Z. Csontos AA, et al. Among authors: tulassay z. Orv Hetil. 2013 May 19;154(20):770-4. doi: 10.1556/OH.2013.29617. Orv Hetil. 2013. PMID: 23666023 Hungarian.
CONCLUSIONS: The frequency of gastric polyps was higher than expected from data published in the literature. Long-term proton pump-inhibitor use and chronic gastritis were associated with fundus gland and hyperplastic polyps, respectively....
CONCLUSIONS: The frequency of gastric polyps was higher than expected from data published in the literature. Long-term proton pump-in …
Early clinical remission and normalisation of CRP are the strongest predictors of efficacy, mucosal healing and dose escalation during the first year of adalimumab therapy in Crohn's disease.
Kiss LS, Szamosi T, Molnar T, Miheller P, Lakatos L, Vincze A, Palatka K, Barta Z, Gasztonyi B, Salamon A, Horvath G, Tóth GT, Farkas K, Banai J, Tulassay Z, Nagy F, Szenes M, Veres G, Lovasz BD, Vegh Z, Golovics PA, Szathmari M, Papp M, Lakatos PL; Hungarian IBD Study Group. Kiss LS, et al. Among authors: tulassay z. Aliment Pharmacol Ther. 2011 Oct;34(8):911-22. doi: 10.1111/j.1365-2036.2011.04827.x. Epub 2011 Aug 24. Aliment Pharmacol Ther. 2011. PMID: 21883326 Free article.
BACKGROUND: Adalimumab is a fully human monoclonal antibody targeting tumour necrosis factor with proven efficacy in the treatment of Crohn's disease (CD). AIM: To investigate the predictors of medium-term clinical efficacy and mucosal healing during adalimumab therapy, in …
BACKGROUND: Adalimumab is a fully human monoclonal antibody targeting tumour necrosis factor with proven efficacy in the treatment of Crohn' …
[Predictors of efficacy, mucosal healing and dose intensification during the first year of adalimumab therapy in patients with luminal and fistulizing Crohn's disease. National data from Hungary].
Kiss LS, Szamosi T, Molnár T, Miheller P, Lakatos L, Vincze A, Palatka K, Bartha Z, Gasztonyi B, Salamon A, Horváth G, Tóth GT, Farkas K, Banai J, Tulassay Z, Nagy F, Szenes M, Veres G, Lovász BD, Végh Z, Golovics PA, Szathmári M, Papp M, Lakatos PL. Kiss LS, et al. Among authors: tulassay z. Orv Hetil. 2011 Sep 4;152(36):1433-42. doi: 10.1556/OH.2011.29200. Orv Hetil. 2011. PMID: 21865144 Hungarian.
The aim of the present study was to investigate the predictors of medium term clinical efficacy and mucosal healing during adalimumab therapy in patients with Crohn's disease in specialized centers approved for biological therapy in Hungary. ...CONCLUSION: Clinical efficac …
The aim of the present study was to investigate the predictors of medium term clinical efficacy and mucosal healing during adalimumab …
27 results