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1986 1
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Exuberant fibroblast activity compromises lung function via ADAMTS4.
Boyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM; PALISI Pediatric Intensive Care Influenza (PICFLU) Investigators; Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG. Boyd DF, et al. Nature. 2020 Nov;587(7834):466-471. doi: 10.1038/s41586-020-2877-5. Epub 2020 Oct 28. Nature. 2020. PMID: 33116313 Free PMC article.
Here we demonstrate that respiratory viral infection induces distinct fibroblast activation states, which we term extracellular matrix (ECM)-synthesizing, damage-responsive and interferon-responsive states. ...
Here we demonstrate that respiratory viral infection induces distinct fibroblast activation states, which we term extracellular matri …
"I Didn't Want My Baby to Pass, But I Didn't Want Him Suffering Either": Comparing Bereaved Parents' Narratives With Nursing End-of-Life Assessments in the Pediatric Intensive Care Unit.
Broden EG, Hinds PS, Werner-Lin AV, Curley MAQ; for the RESTORE Study Investigators. Broden EG, et al. J Hosp Palliat Nurs. 2022 Oct 1;24(5):271-280. doi: 10.1097/NJH.0000000000000884. Epub 2022 Jun 6. J Hosp Palliat Nurs. 2022. PMID: 35666188 Free PMC article.
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, contextualize, and examine comparisons between quantitative trends in children's end-of-life care and parents' qualitative perceptions. ...
Little is known about how nursing care at the end of a child's life impacts long-term parental bereavement. We aimed to explain, cont …
Most High-Intensity Transient Signals Are Not Associated With Specific Surgical Maneuvers.
Twedt MH, Hage BD, Hammel JM, Ibrahimye AN, Shukry M, Qadeer A, Eskridge KM, Truemper EJ, Bashford GR. Twedt MH, et al. Among authors: truemper ej. World J Pediatr Congenit Heart Surg. 2020 Jul;11(4):401-408. doi: 10.1177/2150135120909761. World J Pediatr Congenit Heart Surg. 2020. PMID: 32645775
BACKGROUND: Mortality after congenital heart defect surgery has dropped dramatically in the last few decades. Current research on long-term outcomes has focused on preventing secondary neurological sequelae, for which embolic burden is suspected. ...Future recommended rese …
BACKGROUND: Mortality after congenital heart defect surgery has dropped dramatically in the last few decades. Current research on long-te …
Delirium in Critically Ill Children: An International Point Prevalence Study.
Traube C, Silver G, Reeder RW, Doyle H, Hegel E, Wolfe HA, Schneller C, Chung MG, Dervan LA, DiGennaro JL, Buttram SD, Kudchadkar SR, Madden K, Hartman ME, deAlmeida ML, Walson K, Ista E, Baarslag MA, Salonia R, Beca J, Long D, Kawai Y, Cheifetz IM, Gelvez J, Truemper EJ, Smith RL, Peters ME, O'Meara AM, Murphy S, Bokhary A, Greenwald BM, Bell MJ. Traube C, et al. Among authors: truemper ej. Crit Care Med. 2017 Apr;45(4):584-590. doi: 10.1097/CCM.0000000000002250. Crit Care Med. 2017. PMID: 28079605 Free PMC article.
Further multi-institutional, longitudinal studies are required to investigate effect of delirium on long-term outcomes and possible preventive and treatment measures. Universal delirium screening is practical and can be implemented in pediatric critical care units....
Further multi-institutional, longitudinal studies are required to investigate effect of delirium on long-term outcomes and possible p …
Use of ketamine in asthmatic children to treat respiratory failure refractory to conventional therapy.
Rock MJ, Reyes de la Rocha S, L'Hommedieu CS, Truemper E. Rock MJ, et al. Among authors: truemper e. Crit Care Med. 1986 May;14(5):514-6. doi: 10.1097/00003246-198605000-00019. Crit Care Med. 1986. PMID: 3698618
Except for increased secretions during the infusion, our patients showed no immediate or long-term sequelae from ketamine therapy. However, ketamine should only be used for asthmatics whose respiratory failure does not respond to conventional management and mechanical vent …
Except for increased secretions during the infusion, our patients showed no immediate or long-term sequelae from ketamine therapy. Ho …