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Page 1
Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis.
Lefrancq N, Bouchez V, Fernandes N, Barkoff AM, Bosch T, Dalby T, Åkerlund T, Darenberg J, Fabianova K, Vestrheim DF, Fry NK, González-López JJ, Gullsby K, Habington A, He Q, Litt D, Martini H, Piérard D, Stefanelli P, Stegger M, Zavadilova J, Armatys N, Landier A, Guillot S, Hong SL, Lemey P, Parkhill J, Toubiana J, Cauchemez S, Salje H, Brisse S. Lefrancq N, et al. Among authors: toubiana j. Sci Transl Med. 2022 Apr 27;14(642):eabn3253. doi: 10.1126/scitranslmed.abn3253. Epub 2022 Apr 27. Sci Transl Med. 2022. PMID: 35476597
Increased fitness of pertactin-deficient strains after implementation of acellular vaccines, but reduced fitness otherwise, can explain long-term genotype dynamics. These findings highlight the role of vaccine policy in shifting local diversity of a pathogen that is respon …
Increased fitness of pertactin-deficient strains after implementation of acellular vaccines, but reduced fitness otherwise, can explain long …
Management of Gorham Stout disease with skull-base defects: Case series of six children and literature review.
Simon F, Luscan R, Khonsari RH, Toubiana J, Belhous K, James S, Blauwblomme T, Zerah M, Denoyelle F, Donadieu J, Couloigner V. Simon F, et al. Among authors: toubiana j. Int J Pediatr Otorhinolaryngol. 2019 Sep;124:152-156. doi: 10.1016/j.ijporl.2019.06.002. Epub 2019 Jun 5. Int J Pediatr Otorhinolaryngol. 2019. PMID: 31195309 Review.
Surgery included petrectomy, endonasal surgery for CSF leak management and neurosurgery for medullar management but could not guarantee long-term effects. CONCLUSION: Main issues in skull base defects are CSF leaks and medullar compressions. ...
Surgery included petrectomy, endonasal surgery for CSF leak management and neurosurgery for medullar management but could not guarantee long …
Salvage Strategy for Long-Term Central Venous Catheter-Associated Staphylococcus aureus Infections in Children.
Alby-Laurent F, Lambe C, Ferroni A, Salvi N, Lebeaux D, Le Gouëz M, Castelle M, Moulin F, Nassif X, Lortholary O, Chalumeau M, Toubiana J. Alby-Laurent F, et al. Among authors: toubiana j. Front Pediatr. 2019 Jan 25;6:427. doi: 10.3389/fped.2018.00427. eCollection 2018. Front Pediatr. 2019. PMID: 30740390 Free PMC article.
Methods: We retrospectively analyzed data for all children <18 years having S. aureus CLABSI on a long-term central venous catheter in a tertiary hospital from 2010 to 2014. ...Results: During the study period, 49 cases of S. aureus CLABSI on long-term central ve …
Methods: We retrospectively analyzed data for all children <18 years having S. aureus CLABSI on a long-term central venous cathete …
Association between the COVID-19 pandemic and pertussis derived from multiple nationwide data sources, France, 2013 to 2020.
Matczak S, Levy C, Fortas C, Cohen JF, Béchet S, Aït El Belghiti F, Guillot S, Trombert-Paolantoni S, Jacomo V, Savitch Y, Paireau J, Brisse S, Guiso N, Lévy-Bruhl D, Cohen R, Toubiana J. Matczak S, et al. Among authors: toubiana j. Euro Surveill. 2022 Jun;27(25):2100933. doi: 10.2807/1560-7917.ES.2022.27.25.2100933. Euro Surveill. 2022. PMID: 35748301 Free PMC article.
We conducted a quasi-experimental interrupted time series analysis, relying on negative binomial regression models. The models accounted for seasonality, long-term cycles and secular trend, and included a binary variable for the first national lockdown (start 16 March 2020 …
We conducted a quasi-experimental interrupted time series analysis, relying on negative binomial regression models. The models accounted for …
Sepsis-induced expansion of granulocytic myeloid-derived suppressor cells promotes tumour growth through Toll-like receptor 4.
Llitjos JF, Auffray C, Alby-Laurent F, Rousseau C, Merdji H, Bonilla N, Toubiana J, Belaïdouni N, Mira JP, Lucas B, Chiche JD, Pène F. Llitjos JF, et al. Among authors: toubiana j. J Pathol. 2016 Aug;239(4):473-83. doi: 10.1002/path.4744. Epub 2016 Jun 23. J Pathol. 2016. PMID: 27178223
Severe sepsis remains a frequent and dreaded complication in cancer patients. Beyond the often fatal short-term outcome, the long-term sequelae of severe sepsis may also impact directly on the prognosis of the underlying malignancy in survivors. ...
Severe sepsis remains a frequent and dreaded complication in cancer patients. Beyond the often fatal short-term outcome, the long- …
Incidence of paediatric pneumococcal meningitis and emergence of new serotypes: a time-series analysis of a 16-year French national survey.
Ouldali N, Levy C, Varon E, Bonacorsi S, Béchet S, Cohen R, Angoulvant F; French Pediatric Meningitis Network. Ouldali N, et al. Lancet Infect Dis. 2018 Sep;18(9):983-991. doi: 10.1016/S1473-3099(18)30349-9. Epub 2018 Jul 23. Lancet Infect Dis. 2018. PMID: 30049623
BACKGROUND: Successive implementation of seven-valent then 13-valent pneumococcal conjugate vaccines (PCVs) led to a marked decrease in pneumococcal disease burden, including pneumococcal meningitis. We assessed the long-term effect of implementation of PCVs on incidence o …
BACKGROUND: Successive implementation of seven-valent then 13-valent pneumococcal conjugate vaccines (PCVs) led to a marked decrease in pneu …