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Restoration of metabolic inflammation-related ghrelin resistance by weight loss.
Naznin F, Toshinai K, Waise TMZ, Okada T, Sakoda H, Nakazato M. Naznin F, et al. Among authors: toshinai k. J Mol Endocrinol. 2018 Feb;60(2):109-118. doi: 10.1530/JME-17-0192. Epub 2017 Dec 12. J Mol Endocrinol. 2018. PMID: 29233861 Free PMC article.
High-fat diet (HFD)-induced metabolic inflammation in the central and peripheral organs contributes to the pathogenesis of obesity. Long-term HFD blunts signaling by ghrelin, a gastric-derived orexigenic peptide, in the vagal afferent nerve via a mechanism involving in sit …
High-fat diet (HFD)-induced metabolic inflammation in the central and peripheral organs contributes to the pathogenesis of obesity. Long- …
Peripheral interaction of ghrelin with cholecystokinin on feeding regulation.
Date Y, Toshinai K, Koda S, Miyazato M, Shimbara T, Tsuruta T, Niijima A, Kangawa K, Nakazato M. Date Y, et al. Among authors: toshinai k. Endocrinology. 2005 Aug;146(8):3518-25. doi: 10.1210/en.2004-1240. Epub 2005 May 12. Endocrinology. 2005. PMID: 15890776
We investigated the interaction between ghrelin and CCK functioning in short-term regulation of feeding in Otsuka Long-Evans Tokushima fatty (OLETF) rats, which have a disrupted CCK type A receptor (CCK-AR), and their lean littermates, Long-Evans Tokushima Otsuka (LETO) ra …
We investigated the interaction between ghrelin and CCK functioning in short-term regulation of feeding in Otsuka Long-Evans Tokushim …
Upregulation of ghrelin expression in cachectic nude mice bearing human melanoma cells.
Hanada T, Toshinai K, Date Y, Kajimura N, Tsukada T, Hayashi Y, Kangawa K, Nakazato M. Hanada T, et al. Among authors: toshinai k. Metabolism. 2004 Jan;53(1):84-8. doi: 10.1016/j.metabol.2003.06.004. Metabolism. 2004. PMID: 14681847
This study demonstrates that both ghrelin biosynthesis and secretion are stimulated in the long-term negative energy balance of tumor-inoculated cachectic mice. ...
This study demonstrates that both ghrelin biosynthesis and secretion are stimulated in the long-term negative energy balance of tumor …