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Evaluation of Topical Lysostaphin as a Novel Treatment for Instrumented Rhesus Macaques (Macaca mulatta) Infected with Methicillin-Resistant Staphylococcus aureus.
Cheleuitte-Nieves CE, Diaz LL, Pardos de la Gandara M, Gonzalez A, Freiwald WA, de Lencastre HM, Tomasz A, Euler CW. Cheleuitte-Nieves CE, et al. Among authors: tomasz a. Comp Med. 2020 Oct 1;70(5):335-347. doi: 10.30802/AALAS-CM-19-000102. Epub 2020 Aug 13. Comp Med. 2020. PMID: 32792040 Free PMC article.
Our study suggests that lysostaphin, coupled with other treatment modalities, can decrease MRSA infection short-term but do not completely eradicate MRSA in the long-term. This reappearance of MRSA may be due to cross-contamination or reinfection from other infected …
Our study suggests that lysostaphin, coupled with other treatment modalities, can decrease MRSA infection short-term but do not compl …
Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone.
Croucher NJ, Hanage WP, Harris SR, McGee L, van der Linden M, de Lencastre H, Sá-Leão R, Song JH, Ko KS, Beall B, Klugman KP, Parkhill J, Tomasz A, Kristinsson KG, Bentley SD. Croucher NJ, et al. Among authors: tomasz a. BMC Biol. 2014 Jun 23;12:49. doi: 10.1186/1741-7007-12-49. BMC Biol. 2014. PMID: 24957517 Free PMC article.
CONCLUSIONS: PMEN2's clonal evolution was successful over the short-term in a limited geographical region, but its inability to alter major antigens or 'core' gene sequences associated with resistance may have prevented persistence over longer timespans....
CONCLUSIONS: PMEN2's clonal evolution was successful over the short-term in a limited geographical region, but its inability to alter …