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Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis.
Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk; Cholesterol Treatment Trialists’ (CTT) Collaboration. Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk, et al. Lancet Diabetes Endocrinol. 2024 May;12(5):306-319. doi: 10.1016/S2213-8587(24)00040-8. Epub 2024 Mar 27. Lancet Diabetes Endocrinol. 2024. PMID: 38554713
We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double-blind trials of statin therapy. METHODS: We conducted a meta-analysis of individual participant data from randomised controlled trials of s …
We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double …
Long-term cardiovascular risks and the impact of statin treatment on socioeconomic inequalities: a microsimulation model.
Wu R, Williams C, Zhou J, Schlackow I, Emberson J, Reith C, Keech A, Robson J, Armitage J, Gray A, Simes J, Baigent C, Mihaylova B; CTT Collaboration secretariat; Armitage J, Baigent C, Barnes E, Blackwell L, Collins R, Davies K, Emberson J, Fulcher J, Halls H, Herrington WG, Holland L, Keech A, Kirby A, Mihaylova B, O'Connell R, Preiss D, Reith C, Simes J, Wilson K; CTT Collaboration trialists: A to Z trial (phase Z); Blazing M, Braunwald E, Lemos J, Murphy S, Pedersen TR, Pfeffer M, White H, Wiviott S; AFCAPS/TEXCAPS (AirForce/Texas Coronary Atherosclerosis Prevention Study); Clearfield M, Downs JR, Gotto A Jr, Weis S; ALERT (Assessment of Lescol in Renal Transplantation); Fellström B, Holdaas H, Jardine A, Pedersen TR; ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial); Gordon D, Davis B, Furberg C, Grimm R, Pressel S, Probstfield JL, Rahman M, Simpson L; ALLIANCE (Aggressive Lipid-Lowering Initiation Abates New Cardiac Events); Koren M; ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial); Dahlöf B, Gupta A, Poulter N, Sever P, Wedel H; ASPEN (Atorvastatin Study for the Prevention of Coronary Heart Disease Endpoints in Non-Insulin Dependent Diabe… See abstract for full author list ➔ Wu R, et al. Among authors: tognoni g. Br J Gen Pract. 2024 Feb 19;74(740):e189-98. doi: 10.3399/BJGP.2023.0198. Online ahead of print. Br J Gen Pract. 2024. PMID: 38373851 Free PMC article.
CONCLUSION: The study demonstrated the potential of guideline-recommended statin treatment to reduce socioeconomic inequalities. This CVD model is a novel resource for individualised long-term projections of health outcomes of CVD treatments....
CONCLUSION: The study demonstrated the potential of guideline-recommended statin treatment to reduce socioeconomic inequalities. This CVD mo …
Long-term beneficial impact of the randomised trial 'Train the Brain', a motor/cognitive intervention in mild cognitive impairment people: effects at the 14-month follow-up.
Sale A, Noale M, Cintoli S, Tognoni G, Braschi C, Berardi N, Maggi S, Maffei L; Train the Brain Consortium. Sale A, et al. Among authors: tognoni g. Age Ageing. 2023 May 1;52(5):afad067. doi: 10.1093/ageing/afad067. Age Ageing. 2023. PMID: 37167616 Clinical Trial.
The 'Train the Brain' programme is a combined motor and cognitive intervention previously shown to markedly improve cognitive functions in MCI individuals compared to non-trained MCI controls, as assessed at the end of the 7-month intervention. Here, we extended the previous anal …
The 'Train the Brain' programme is a combined motor and cognitive intervention previously shown to markedly improve cognitive functions in M …
Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials.
Cholesterol Treatment Trialists' Collaboration. Cholesterol Treatment Trialists' Collaboration. Lancet. 2022 Sep 10;400(10355):832-845. doi: 10.1016/S0140-6736(22)01545-8. Epub 2022 Aug 29. Lancet. 2022. PMID: 36049498 Free PMC article.
We aimed to address these through an individual participant data meta-analysis of all recorded adverse muscle events in large, long-term, randomised, double-blind trials of statin therapy. METHODS: Randomised trials of statin therapy were eligible if they aimed to recruit …
We aimed to address these through an individual participant data meta-analysis of all recorded adverse muscle events in large, long-term …
[Cultural meta-analysis 2: the after Covid-19].
Tognoni G. Tognoni G. Assist Inferm Ric. 2021 Apr-Jun;40(2):101-107. doi: 10.1702/3634.36148. Assist Inferm Ric. 2021. PMID: 34180913 Italian.
Its 'syndemic' nature (i.e. its interaction with structural, permanent, economic, social, cultural pandemics) imposes the acceptance and the long-term pursuit of new civilisation paradigms. Health care is definitely one of the areas where this cultural challenge must be me …
Its 'syndemic' nature (i.e. its interaction with structural, permanent, economic, social, cultural pandemics) imposes the acceptance and the …
Obstructive sleep apnea syndrome and Alzheimer's disease pathology: may continuous positive airway pressure treatment delay cognitive deterioration?
Liguori C, Cremascoli R, Maestri M, Fernandes M, Izzi F, Tognoni G, Scarpina F, Siciliano G, Mercuri NB, Priano L, Bonanni E, Placidi F. Liguori C, et al. Among authors: tognoni g. Sleep Breath. 2021 Dec;25(4):2135-2139. doi: 10.1007/s11325-021-02320-4. Epub 2021 Feb 22. Sleep Breath. 2021. PMID: 33619666
PURPOSE: The main aim of the present study was to identify the long-term effects of continuous positive airway pressure (CPAP) treatment in patients co-affected by obstructive sleep apnea syndrome (OSAS) and mild cognitive impairment (MCI) or dementia due to Alzheimer's di …
PURPOSE: The main aim of the present study was to identify the long-term effects of continuous positive airway pressure (CPAP) treatm …
[When, how, why and whom for there will be an "after" Covid-19?].
Tognoni G. Tognoni G. Assist Inferm Ric. 2020 Jul-Sep;39(3):147-153. doi: 10.1702/3454.34432. Assist Inferm Ric. 2020. PMID: 33077984 Italian.
The importance of the nursing component of the organisation and of the technical and cultural aspects of health care delivery and accessibility has been underlined as a protagonist of the resistance and resilience during the worst period of the emergency, and should be specifical …
The importance of the nursing component of the organisation and of the technical and cultural aspects of health care delivery and accessibil …
Cardiovascular mortality and morbidity burden in successive and age pre-stratified case-control cohorts of breast cancer women. A population-based study.
Staszewsky L, Robusto F, Lepore V, Bisceglia L, Petrarolo V, D'Ettorre A, Tognoni G, Latini R. Staszewsky L, et al. Among authors: tognoni g. Breast Cancer Res Treat. 2020 Aug;183(1):177-188. doi: 10.1007/s10549-020-05758-4. Epub 2020 Jun 25. Breast Cancer Res Treat. 2020. PMID: 32588164
While younger patients seems to tolerate BC and BC therapy better in the short term, HF mortality and morbidity resulted significantly increased at 5-year follow-up. ...
While younger patients seems to tolerate BC and BC therapy better in the short term, HF mortality and morbidity resulted significantl …
[I promotori di salute come attori-protagonisti delle cure primarie nel controllo delle malattie comunicabili e non comunicabili e nell' empowerment delle comunità. Esperienza e risultati di lungo periodo in aree marginali in Ecuador dal 1980 al 2018.].
Caicedo C, Anselmi M, Prandi R, Márquez M, Buonfrate BD, Gobbi F, Bisoffi Z, Tognoni G. Caicedo C, et al. Among authors: tognoni g. Assist Inferm Ric. 2020 Jan-Mar;39(1):47-56. doi: 10.1702/3371.33476. Assist Inferm Ric. 2020. PMID: 32458830 Italian.
Long-Term Outcomes of a Cohort of Hypertensive Subjects in Rural Ecuador.
Moreira J, Figueroa MM, Anselmi M, Prandi R, Montaño CC, Bell D, Betancour O, Robusto F, Vannini T, Avanzini F, Tognoni G, Roncaglioni MC; COHEMI Project Study Group. Moreira J, et al. Among authors: tognoni g. Glob Heart. 2019 Dec;14(4):373-378. doi: 10.1016/j.gheart.2019.09.001. Glob Heart. 2019. PMID: 31727267 Free article.
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