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Protocol design and synopsis: Omalizumab as Monotherapy and as Adjunct Therapy to Multiallergen OIT in Children and Adults with Food Allergy (OUtMATCH).
Wood RA, Chinthrajah RS, Rudman Spergel AK, Babineau DC, Sicherer SH, Kim EH, Shreffler WG, Jones SM, Leung DYM, Vickery BP, Bird JA, Spergel JM, Kulis M, Iqbal A, Kaufman D, Umetsu DT, Ligueros-Saylan M, Uddin A, Fogel RB, Lussier S, Mudd K, Poyser J, MacPhee M, Veri M, Davidson W, Hamrah S, Long A, Togias A; OUtMATCH study team. Wood RA, et al. Among authors: togias a. J Allergy Clin Immunol Glob. 2022 Jul 21;1(4):225-232. doi: 10.1016/j.jacig.2022.05.006. eCollection 2022 Nov. J Allergy Clin Immunol Glob. 2022. PMID: 37779534 Free PMC article.
Second, stage 2 will directly compare treatment of patients with multifood allergies using omalizumab as monotherapy versus treatment with omalizumab-facilitated multiallergen oral immunotherapy in which omalizumab is used as an adjunctive treatment. Third, stage 3 will address t …
Second, stage 2 will directly compare treatment of patients with multifood allergies using omalizumab as monotherapy versus treatment with o …
Synchronous immune alterations mirror clinical response during allergen immunotherapy.
Renand A, Shamji MH, Harris KM, Qin T, Wambre E, Scadding GW, Wurtzen PA, Till SJ, Togias A, Nepom GT, Kwok WW, Durham SR. Renand A, et al. Among authors: togias a. J Allergy Clin Immunol. 2018 May;141(5):1750-1760.e1. doi: 10.1016/j.jaci.2017.09.041. Epub 2017 Nov 9. J Allergy Clin Immunol. 2018. PMID: 29128670 Free PMC article.
BACKGROUND: Three years of treatment with either sublingual or subcutaneous allergen immunotherapy has been shown to be effective and to induce long-term tolerance. The Gauging Response in Allergic Rhinitis to Sublingual and Subcutaneous Immunotherapy (GRASS) trial demonst …
BACKGROUND: Three years of treatment with either sublingual or subcutaneous allergen immunotherapy has been shown to be effective and to ind …
Reducing Exacerbations in the Inner City: Lessons from the Inner-City Asthma Consortium (ICAC).
Gergen PJ, Teach SJ, Togias A, Busse WW. Gergen PJ, et al. Among authors: togias a. J Allergy Clin Immunol Pract. 2016 Jan-Feb;4(1):22-6. doi: 10.1016/j.jaip.2015.07.024. Epub 2015 Nov 14. J Allergy Clin Immunol Pract. 2016. PMID: 26589178 Free PMC article. Review.
Despite this year around aggressive therapy, exacerbations remain albeit at a lower level and with less seasonal variation. Another strategy, the short term use of therapy aimed at reducing the role of allergy begun before the fall season and focused on individuals at high …
Despite this year around aggressive therapy, exacerbations remain albeit at a lower level and with less seasonal variation. Another strategy …
Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations.
Teach SJ, Gill MA, Togias A, Sorkness CA, Arbes SJ Jr, Calatroni A, Wildfire JJ, Gergen PJ, Cohen RT, Pongracic JA, Kercsmar CM, Khurana Hershey GK, Gruchalla RS, Liu AH, Zoratti EM, Kattan M, Grindle KA, Gern JE, Busse WW, Szefler SJ. Teach SJ, et al. Among authors: togias a. J Allergy Clin Immunol. 2015 Dec;136(6):1476-1485. doi: 10.1016/j.jaci.2015.09.008. Epub 2015 Oct 27. J Allergy Clin Immunol. 2015. PMID: 26518090 Free PMC article. Clinical Trial.
BACKGROUND: Short-term targeted treatment can potentially prevent fall asthma exacerbations while limiting therapy exposure. ...
BACKGROUND: Short-term targeted treatment can potentially prevent fall asthma exacerbations while limiting therapy exposure. ...
Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report.
Papadopoulos NG, Bernstein JA, Demoly P, Dykewicz M, Fokkens W, Hellings PW, Peters AT, Rondon C, Togias A, Cox LS. Papadopoulos NG, et al. Among authors: togias a. Allergy. 2015 May;70(5):474-94. doi: 10.1111/all.12573. Epub 2015 Feb 19. Allergy. 2015. PMID: 25620381
Rhinitis is an umbrella term that encompasses many different subtypes, several of which still elude complete characterization. ...
Rhinitis is an umbrella term that encompasses many different subtypes, several of which still elude complete characterization. ...
Comparison of the etiology of viral respiratory illnesses in inner-city and suburban infants.
Gern JE, Pappas T, Visness CM, Jaffee KF, Lemanske RF, Togias A, Bloomberg GR, Cruikshank WW, Lamm C, Tuzova M, Wood RA, Lee WM. Gern JE, et al. Among authors: togias a. J Infect Dis. 2012 Nov;206(9):1342-9. doi: 10.1093/infdis/jis504. Epub 2012 Sep 25. J Infect Dis. 2012. PMID: 23014674 Free PMC article.
These findings raise important questions about the etiology of virus-negative illnesses in urban infants and the possibility of long-term consequences of early life infections with adenovirus in this population....
These findings raise important questions about the etiology of virus-negative illnesses in urban infants and the possibility of long-term
Rhinosinusitis: establishing definitions for clinical research and patient care.
Meltzer EO, Hamilos DL, Hadley JA, Lanza DC, Marple BF, Nicklas RA, Bachert C, Baraniuk J, Baroody FM, Benninger MS, Brook I, Chowdhury BA, Druce HM, Durham S, Ferguson B, Gwaltney JM, Kaliner M, Kennedy DW, Lund V, Naclerio R, Pawankar R, Piccirillo JF, Rohane P, Simon R, Slavin RG, Togias A, Wald ER, Zinreich SJ; American Academy of Allergy, Asthma and Immunology (AAAAI); American Academy of Otolaryngic Allergy (AAOA); American Academy of Otolaryngology--Head and Neck Surgery (AAO-HNS); American College of Allergy, Asthma and Immunology (ACAAI); American Rhinologic Society (ARS). Meltzer EO, et al. Among authors: togias a. J Allergy Clin Immunol. 2004 Dec;114(6 Suppl):155-212. doi: 10.1016/j.jaci.2004.09.029. J Allergy Clin Immunol. 2004. PMID: 15577865 Free PMC article. Review.
Over two days, the panel developed definitions for rhinosinusitis and outlined strategies for design of clinical trials. RESULTS: Committee members agreed to adopt the term "rhinosinusitis" and reached consensus on definitions and strategies for clinical research on acute …
Over two days, the panel developed definitions for rhinosinusitis and outlined strategies for design of clinical trials. RESULTS: Committee …
Rhinosinusitis: Establishing definitions for clinical research and patient care.
Meltzer EO, Hamilos DL, Hadley JA, Lanza DC, Marple BF, Nicklas RA, Bachert C, Baraniuk J, Baroody FM, Benninger MS, Brook I, Chowdhury BA, Druce HM, Durham S, Ferguson B, Gwaltney JM Jr, Kaliner M, Kennedy DW, Lund V, Naclerio R, Pawankar R, Piccirillo JF, Rohane P, Simon R, Slavin RG, Togias A, Wald ER, Zinreich SJ; American Academy of Allergy, Asthma and Immunology; American Academy of Otolaryngic Allergy; American Academy of Otolaryngology-Head and Neck Surgery; American College of Allergy, Asthma and Immunology; American Rhinologic Society. Meltzer EO, et al. Among authors: togias a. Otolaryngol Head Neck Surg. 2004 Dec;131(6 Suppl):S1-62. doi: 10.1016/j.otohns.2004.09.067. Otolaryngol Head Neck Surg. 2004. PMID: 15577816 Free PMC article. Review.
Over two days, the panel developed definitions for rhinosinusitis and outlined strategies for design of clinical trials. RESULTS: Committee members agreed to adopt the term "rhinosinusitis" and reached consensus on definitions and strategies for clinical research on acute …
Over two days, the panel developed definitions for rhinosinusitis and outlined strategies for design of clinical trials. RESULTS: Committee …