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Impact of mild and moderate/severe vertebral fractures on physical activity: a prospective study of older women in the UK.
Al-Sari UA, Tobias JH, Clark EM. Al-Sari UA, et al. Among authors: tobias jh. Osteoporos Int. 2019 Jan;30(1):155-166. doi: 10.1007/s00198-018-4692-5. Epub 2018 Sep 7. Osteoporos Int. 2019. PMID: 30194466
Little is known about the long-term impact of vertebral fractures on physical activity. There is also uncertainty over the clinical significance of mild vertebral fracture. We showed that women with moderate/severe but not mild vertebral fracture do less walking duration a …
Little is known about the long-term impact of vertebral fractures on physical activity. There is also uncertainty over the clinical s …
Placental Size Is Associated Differentially With Postnatal Bone Size and Density.
Holroyd CR, Osmond C, Barker DJ, Ring SM, Lawlor DA, Tobias JH, Smith GD, Cooper C, Harvey NC. Holroyd CR, et al. Among authors: tobias jh. J Bone Miner Res. 2016 Oct;31(10):1855-1864. doi: 10.1002/jbmr.2840. Epub 2016 Apr 22. J Bone Miner Res. 2016. PMID: 26999363 Free PMC article. Clinical Trial.
The Avon Longitudinal Study of Parents and Children (ALSPAC) recruited pregnant women from the southwest of England between 1991 and 1993. There were 12,942 singleton babies born at term who survived at least the first 12 months. From these, 8933 placentas were preserved i …
The Avon Longitudinal Study of Parents and Children (ALSPAC) recruited pregnant women from the southwest of England between 1991 and 1993. T …
An exploration of barriers and facilitators to older adults' participation in higher impact physical activity and bone health: a qualitative study.
Simmonds BAJ, Hannam KJ, Fox KR, Tobias JH. Simmonds BAJ, et al. Among authors: tobias jh. Osteoporos Int. 2016 Mar;27(3):979-987. doi: 10.1007/s00198-015-3376-7. Epub 2015 Nov 10. Osteoporos Int. 2016. PMID: 26556738 Free PMC article.
Ways in which high-impact physical activity can be habitualised into everyday activities, be fun and interactive may help facilitate longer term adoption....
Ways in which high-impact physical activity can be habitualised into everyday activities, be fun and interactive may help facilitate longer …
Maternal Preeclampsia Is Associated With Reduced Adolescent Offspring Hip BMD in a UK Population-Based Birth Cohort.
Hannam K, Lawlor DA, Tobias JH. Hannam K, et al. Among authors: tobias jh. J Bone Miner Res. 2015 Sep;30(9):1684-91. doi: 10.1002/jbmr.2506. Epub 2015 May 14. J Bone Miner Res. 2015. PMID: 25761963 Free PMC article.
A suboptimal intrauterine environment has been postulated to have adverse long-term health effects, including an increased risk of osteoporosis. ...This association was not attenuated by further adjustment for gestational age and birth weight, which were hypothesize …
A suboptimal intrauterine environment has been postulated to have adverse long-term health effects, including an increased risk of os …
Adiponectin and its association with bone mass accrual in childhood.
Sayers A, Timpson NJ, Sattar N, Deanfield J, Hingorani AD, Davey-Smith G, Tobias JH. Sayers A, et al. Among authors: tobias jh. J Bone Miner Res. 2010 Oct;25(10):2212-20. doi: 10.1002/jbmr.116. J Bone Miner Res. 2010. PMID: 20499348 Free article.
We examined this question using the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort by investigating relationships between circulating adiponectin levels at a mean age of 9.9 years, indices of bone mass as measured by total-body dual-energy X-ray abso …
We examined this question using the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort by investigating relationsh …
Novel therapeutic targets in osteoporosis.
Tobias JH, Flanagan AM, Scutt AM. Tobias JH, et al. Expert Opin Ther Targets. 2002 Feb;6(1):41-56. doi: 10.1517/14728222.6.1.41. Expert Opin Ther Targets. 2002. PMID: 11901480 Review.
Several licensed therapies are available to treat this condition, which suffer from several disadvantages including limited efficacy, high cost and poor long-term patient adherence as a consequence of significant side effects and inconvenient methods of administration. ...
Several licensed therapies are available to treat this condition, which suffer from several disadvantages including limited efficacy, high c …
Intermittent retinoic acid in combination with continuous oestradiol-17 beta increases cancellous bone volume in osteopaenic ovariectomized rats.
Tobias JH, Gallagher A, Chambers TJ. Tobias JH, et al. J Endocrinol. 1994 Jul;142(1):61-7. doi: 10.1677/joe.0.1420061. J Endocrinol. 1994. PMID: 7964285
Although short-term administration of oestradiol-17 beta (OE2) stimulates cancellous bone formation in the rat, this is replaced by a tendency to suppression after prolonged treatment. ...
Although short-term administration of oestradiol-17 beta (OE2) stimulates cancellous bone formation in the rat, this is replaced by a …