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Prospective Cohort Study to Compare Long-Term Lung Cancer-Specific and All-Cause Survival of Clinical Early Stage (T1a-b; 20 mm) NSCLC Treated by Stereotactic Body Radiation Therapy and Surgery.
Henschke CI, Yip R, Sun Q, Li P, Kaufman A, Samstein R, Connery C, Kohman L, Lee P, Tannous H, Yankelevitz DF, Taioli E, Rosenzweig K, Flores RM; I-ELCAP; IELCART Investigators. Henschke CI, et al. J Thorac Oncol. 2024 Mar;19(3):476-490. doi: 10.1016/j.jtho.2023.10.002. Epub 2023 Oct 6. J Thorac Oncol. 2024. PMID: 37806384
CONCLUSIONS: This first prospectively collected cohort analysis of long-term survival of small, early NSCLCs revealed that lung cancer-specific survival was high for both treatments and not significantly different (p = 0.48) and that all-cause survival after propensity mat …
CONCLUSIONS: This first prospectively collected cohort analysis of long-term survival of small, early NSCLCs revealed that lung cance …
Characterization of Newly Detected Costal Pleura-attached Noncalcified Nodules at Annual Low-Dose CT Screenings.
Zhu Y, Yip R, You N, Cai Q, Henschke CI, Yankelevitz DF; International Early Lung Cancer Action Program Investigators; International Early Lung Cancer Action Program Investigators. Zhu Y, et al. Radiology. 2021 Dec;301(3):724-731. doi: 10.1148/radiol.2021210807. Epub 2021 Sep 21. Radiology. 2021. PMID: 34546130
Background Solid costal pleura-attached noncalcified nodules (CP-NCNs) less than 10.0 mm with lentiform, oval, or semicircular (LOS) or triangular shapes and smooth margins on baseline low-dose CT scans from the Mount Sinai Early Lung and Cardiac Action Program (MS-ELCAP) were re …
Background Solid costal pleura-attached noncalcified nodules (CP-NCNs) less than 10.0 mm with lentiform, oval, or semicircular (LOS) or tria …
Survival with Parenchymal and Pleural Invasion of Non-Small Cell Lung Cancers Less than 30 mm.
Yip R, Ma T, Flores RM, Yankelevitz D, Henschke CI; International Early Lung Cancer Action Program Investigators. Yip R, et al. J Thorac Oncol. 2019 May;14(5):890-902. doi: 10.1016/j.jtho.2019.01.013. Epub 2019 Jan 24. J Thorac Oncol. 2019. PMID: 30685507 Free article.
OBJECTIVE: To determine long-term survival of visceral pleural invasion (VPI) and parenchymal invasion (PAI) (angiolymphatic and/or vascular) on survival of NSCLCs less than 30 mm in maximum diameter. ...
OBJECTIVE: To determine long-term survival of visceral pleural invasion (VPI) and parenchymal invasion (PAI) (angiolymphatic and/or v …
Baseline and annual repeat rounds of screening: implications for optimal regimens of screening.
Henschke CI, Salvatore M, Cham M, Powell CA, DiFabrizio L, Flores R, Kaufman A, Eber C, Yip R, Yankelevitz DF; International Early Lung Cancer Action Program Investigators. Henschke CI, et al. Eur Radiol. 2018 Mar;28(3):1085-1094. doi: 10.1007/s00330-017-5029-z. Epub 2017 Oct 5. Eur Radiol. 2018. PMID: 28983713

Percentages of lung cancers by cell type were significantly different (p < 0.0001) in the baseline round compared with annual rounds, reflecting length bias, as were the ratios, reflecting lead times. Long-term K-M survival rate was 100% for typical carcinoids and for a

…

Percentages of lung cancers by cell type were significantly different (p < 0.0001) in the baseline round compared with annual rounds, ref

…
Computed Tomography Screening for Lung Cancer: Mediastinal Lymph Node Resection in Stage IA Nonsmall Cell Lung Cancer Manifesting as Subsolid and Solid Nodules.
Flores RM, Nicastri D, Bauer T, Aye R, Andaz S, Kohman L, Sheppard B, Mayfield W, Thurer R, Korst R, Straznicka M, Grannis F, Pass H, Connery C, Yip R, Smith JP, Yankelevitz DF, Henschke CI, Altorki NK; Writing committee for the I-ELCAP Investigators. Flores RM, et al. Among authors: thurer r. Ann Surg. 2017 May;265(5):1025-1033. doi: 10.1097/SLA.0000000000001802. Ann Surg. 2017. PMID: 27232256 Free PMC article.
OBJECTIVE: To compare long-term survival rates of patients with first, primary, clinical stage IA nonsmall cell lung cancer from a large cohort undergoing computed tomography screening with and without mediastinal lymph node resection (MLNR) under an Institutional Review B …
OBJECTIVE: To compare long-term survival rates of patients with first, primary, clinical stage IA nonsmall cell lung cancer from a la …
CT Screening for Lung Cancer: Nonsolid Nodules in Baseline and Annual Repeat Rounds.
Yankelevitz DF, Yip R, Smith JP, Liang M, Liu Y, Xu DM, Salvatore MM, Wolf AS, Flores RM, Henschke CI; International Early Lung Cancer Action Program Investigators Group. Yankelevitz DF, et al. Radiology. 2015 Nov;277(2):555-64. doi: 10.1148/radiol.2015142554. Epub 2015 Jun 23. Radiology. 2015. PMID: 26101879 Free PMC article.
PURPOSE: To address the frequency of identifying nonsolid nodules, diagnosing lung cancer manifesting as such nodules, and the long-term outcome after treatment in a prospective cohort, the International Early Lung Cancer Action Program. ...
PURPOSE: To address the frequency of identifying nonsolid nodules, diagnosing lung cancer manifesting as such nodules, and the long-term …
Implementation of a comprehensive blood conservation program can reduce blood use in a community cardiac surgery program.
Xydas S, Magovern CJ, Slater JP, Brown JM 3rd, Bustami R, Parr GV, Thurer RL. Xydas S, et al. Among authors: thurer rl. J Thorac Cardiovasc Surg. 2012 Apr;143(4):926-35. doi: 10.1016/j.jtcvs.2012.01.003. Epub 2012 Jan 27. J Thorac Cardiovasc Surg. 2012. PMID: 22285327 Free article.
Further research will determine the effects of reduced transfusions on long-term outcomes....
Further research will determine the effects of reduced transfusions on long-term outcomes....
On-pump versus off-pump coronary-artery bypass surgery.
Shroyer AL, Grover FL, Hattler B, Collins JF, McDonald GO, Kozora E, Lucke JC, Baltz JH, Novitzky D; Veterans Affairs Randomized On/Off Bypass (ROOBY) Study Group. Shroyer AL, et al. N Engl J Med. 2009 Nov 5;361(19):1827-37. doi: 10.1056/NEJMoa0902905. N Engl J Med. 2009. PMID: 19890125 Free article. Clinical Trial.
The primary long-term end point was a composite of death from any cause, a repeat revascularization procedure, or a nonfatal myocardial infarction within 1 year after surgery. ...There were no treatment-based differences in neuropsychological outcomes or short-term …
The primary long-term end point was a composite of death from any cause, a repeat revascularization procedure, or a nonfatal myocardi …
Phase II trial of sequential chemotherapy followed by chemoradiation, surgery, and postoperative chemotherapy for the treatment of stage IIIA/IIIB non-small-cell lung cancer.
Lam P, Berman S, Thurer R, Ashiku S, DeCamp M, Goldstein M, Schumer S, Halmos B, Karp D, Coute D, Bergman M, Boyd-Sirard C, Ou SH, Muzikansky A, Woodard C, Huberman M. Lam P, et al. Among authors: thurer r. Clin Lung Cancer. 2006 Sep;8(2):122-9. doi: 10.3816/CLC.2006.n.040. Clin Lung Cancer. 2006. PMID: 17026813 Clinical Trial.
Postoperative chemotherapy after initial combined modality therapy is often not feasible, reinforcing the value of initial systemic therapy. Long-term results are still suboptimal and await studies adding targeted therapies to our usual chemotherapy/radiation approaches... …
Postoperative chemotherapy after initial combined modality therapy is often not feasible, reinforcing the value of initial systemic therapy. …
Factors affecting late survival after surgical remodeling of left ventricular aneurysms.
Bolooki H, DeMarchena E, Mallon SM, Katariya K, Barron M, Bolooki HM, Thurer RJ, Novak S, Duncan RC. Bolooki H, et al. Among authors: thurer rj. J Thorac Cardiovasc Surg. 2003 Aug;126(2):374-83; discussion 383-5. doi: 10.1016/s0022-5223(03)00023-0. J Thorac Cardiovasc Surg. 2003. PMID: 12928633 Free article.
OBJECTIVES: Surgical remodeling of the left ventricle has involved various techniques of volume reduction. This study evaluates factors that influence long-term survival results with 3 operative methods. METHODS: From 1979 to 2000, 157 patients (134 men, mean age 61 years) …
OBJECTIVES: Surgical remodeling of the left ventricle has involved various techniques of volume reduction. This study evaluates factors that …
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