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Two-year outcomes following a randomised platelet transfusion trial in preterm infants.
Moore CM, D'Amore A, Fustolo-Gunnink S, Hudson C, Newton A, Santamaria BL, Deary A, Hodge R, Hopkins V, Mora A, Llewelyn C, Venkatesh V, Khan R, Willoughby K, Onland W, Fijnvandraat K, New HV, Clarke P, Lopriore E, Watts T, Stanworth S, Curley A; PlaNeT2 MATISSE. Moore CM, et al. Arch Dis Child Fetal Neonatal Ed. 2023 Sep;108(5):452-457. doi: 10.1136/archdischild-2022-324915. Epub 2023 Feb 21. Arch Dis Child Fetal Neonatal Ed. 2023. PMID: 36810309 Free PMC article.
INTERVENTIONS: Infants were randomised to undergo a platelet transfusion at platelet count thresholds of 5010(9)/L (higher threshold group) or 2510(9)/L (lower threshold group). MAIN OUTCOMES MEASURES: Our prespecified long-term follow-up outcome was a composite of death o …
INTERVENTIONS: Infants were randomised to undergo a platelet transfusion at platelet count thresholds of 5010(9)/L (higher threshold group) …
A Longitudinal Study Exploring the Role of Mental Health Symptoms and Social Support Regarding Life Satisfaction 18 Months after Initiation of Gender-Affirming Hormone Treatment.
Aldridge Z, Thorne N, Bouman WP, Witcomb GL, Arcelus J. Aldridge Z, et al. Among authors: thorne n. Healthcare (Basel). 2023 Jan 29;11(3):379. doi: 10.3390/healthcare11030379. Healthcare (Basel). 2023. PMID: 36766954 Free PMC article.
The lack of significant differences in life satisfaction at 18 months post-GAHT based on pre-GAHT mental health, coupled with no evidence for the predictive role social support suggest that these factors are not central to long-term life satisfaction. For many, lower menta …
The lack of significant differences in life satisfaction at 18 months post-GAHT based on pre-GAHT mental health, coupled with no evidence fo …
Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: phase III randomised controlled trial and economic evaluation.
Webb NJA, Woolley RL, Lambe T, Frew E, Brettell EA, Barsoum EN, Trompeter RS, Cummins C, Deeks JJ, Wheatley K, Ives NJ; PREDNOS Collaborative Group. Webb NJA, et al. BMJ. 2019 May 23;365:l1800. doi: 10.1136/bmj.l1800. BMJ. 2019. PMID: 31335316 Free PMC article. Clinical Trial.
CONCLUSIONS: Clinical outcomes did not improve when the initial course of prednisolone treatment was extended from eight to 16 weeks in UK children with steroid sensitive nephrotic syndrome. However, evidence was found of a short term health economic benefit through reduce …
CONCLUSIONS: Clinical outcomes did not improve when the initial course of prednisolone treatment was extended from eight to 16 weeks in UK c …
The terminology of identities between, outside and beyond the gender binary - A systematic review.
Thorne N, Yip AK, Bouman WP, Marshall E, Arcelus J. Thorne N, et al. Int J Transgend. 2019 Jul 18;20(2-3):138-154. doi: 10.1080/15532739.2019.1640654. eCollection 2019. Int J Transgend. 2019. PMID: 32999602 Free PMC article. Review.
However, "gender diverse" is emerging as a more suitable wide-ranging inclusive term for non-male and non-female identities. Discussion: Identity outside of "male" and "female" is an emerging concept which currently has several identifiers and little academic agreement on …
However, "gender diverse" is emerging as a more suitable wide-ranging inclusive term for non-male and non-female identities. Discussi …
An Emerging Female Phenotype with Loss-of-Function Mutations in the Aristaless-Related Homeodomain Transcription Factor ARX.
Mattiske T, Moey C, Vissers LE, Thorne N, Georgeson P, Bakshi M, Shoubridge C. Mattiske T, et al. Among authors: thorne n. Hum Mutat. 2017 May;38(5):548-555. doi: 10.1002/humu.23190. Epub 2017 Feb 15. Hum Mutat. 2017. PMID: 28150386
Two male siblings presenting with XLAG were deceased prior to full-term gestation or within the first few weeks of life. Of the two female siblings, one presented with behavioral disturbances, mild ID, a seizure disorder, and complete agenesis of the corpus callosum (ACC), …
Two male siblings presenting with XLAG were deceased prior to full-term gestation or within the first few weeks of life. Of the two f …
High-throughput viability assay using an autonomously bioluminescent cell line with a bacterial Lux reporter.
Class B, Thorne N, Aguisanda F, Southall N, McKew JC, Zheng W. Class B, et al. Among authors: thorne n. J Lab Autom. 2015 Apr;20(2):164-74. doi: 10.1177/2211068214560608. Epub 2014 Dec 1. J Lab Autom. 2015. PMID: 25447977
We optimized and validated a reagent-addition-free cell viability assay using an autoluminescent HEK293 cell line that stably expresses bacterial luciferase and all substrates necessary for bioluminescence. This cell viability assay can be used for real-time, long-term mea …
We optimized and validated a reagent-addition-free cell viability assay using an autoluminescent HEK293 cell line that stably expresses bact …