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Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. DESIGN, SETTING, AN …
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: T …
Contrasting long-term dynamics of antimicrobial resistance and virulence plasmids in Salmonella Typhimurium from animals.
Mellor KC, Blackwell GA, Cawthraw SA, Mensah NE, Reid SWJ, Thomson NR, Petrovska L, Mather AE. Mellor KC, et al. Among authors: thomson nr. Microb Genom. 2022 Aug;8(8):mgen000826. doi: 10.1099/mgen.0.000826. Microb Genom. 2022. PMID: 35997596 Free PMC article.
Salmonella Typhimurium is the second most common cause of salmonellosis in humans and livestock in the UK and Europe. The long-term dynamics of plasmids between S. Typhimurium were investigated using isolates collected through national surveillance of animals in England an …
Salmonella Typhimurium is the second most common cause of salmonellosis in humans and livestock in the UK and Europe. The long-term d …
Transport and targeted binding of Pluronic-coated nanoparticles in unsaturated porous media.
Jaberi N, Linley S, Thomson NR, McVey K, Sra K, Gu FX. Jaberi N, et al. Among authors: thomson nr. J Contam Hydrol. 2022 Aug;249:104046. doi: 10.1016/j.jconhyd.2022.104046. Epub 2022 Jun 22. J Contam Hydrol. 2022. PMID: 35785549
As a result of the lower NP polymer concentration coating used to promote increased attachment to crude oil, higher retention was observed near the column inlet and was captured quantitatively by adding a depth-dependent straining term to the model. This retention behaviou …
As a result of the lower NP polymer concentration coating used to promote increased attachment to crude oil, higher retention was observed n …
Genomic Characteristics of Recently Recognized Vibrio cholerae El Tor Lineages Associated with Cholera in Bangladesh, 1991 to 2017.
Monir MM, Hossain T, Morita M, Ohnishi M, Johura FT, Sultana M, Monira S, Ahmed T, Thomson N, Watanabe H, Huq A, Colwell RR, Seed K, Alam M. Monir MM, et al. Among authors: thomson n. Microbiol Spectr. 2022 Apr 27;10(2):e0039122. doi: 10.1128/spectrum.00391-22. Epub 2022 Mar 22. Microbiol Spectr. 2022. PMID: 35315699 Free PMC article.
Results of an in-depth genomic study of V. cholerae associated with endemic cholera during the past 27 years (1991 to 2017) indicate emergence and succession of the two lineages, BD-1 and BD-2, arising from a common ancestral paraphyletic group, BD-0, comprising the early strains …
Results of an in-depth genomic study of V. cholerae associated with endemic cholera during the past 27 years (1991 to 2017) indicate emergen …
An inducible transposon mutagenesis approach for the intracellular human pathogen Chlamydia trachomatis.
O'Neill CE, Skilton RJ, Forster J, Cleary DW, Pearson SA, Lampe DJ, Thomson NR, Clarke IN. O'Neill CE, et al. Among authors: thomson nr. Wellcome Open Res. 2021 Nov 16;6:312. doi: 10.12688/wellcomeopenres.16068.1. eCollection 2021. Wellcome Open Res. 2021. PMID: 35087955 Free PMC article.
Background: Chlamydia trachomatis is a prolific human pathogen that can cause serious long-term conditions if left untreated. Recent developments in Chlamydia genetics have opened the door to conducting targeted and random mutagenesis experiments to identify gene function. …
Background: Chlamydia trachomatis is a prolific human pathogen that can cause serious long-term conditions if left untreated. Recent …
The Nature and Extent of Plasmid Variation in Chlamydia trachomatis.
Jones CA, Hadfield J, Thomson NR, Cleary DW, Marsh P, Clarke IN, O'Neill CE. Jones CA, et al. Among authors: thomson nr. Microorganisms. 2020 Mar 6;8(3):373. doi: 10.3390/microorganisms8030373. Microorganisms. 2020. PMID: 32155798 Free PMC article.
This is crucial at a time when single-target diagnostic assays are failing to detect natural mutants, putting those infected at risk of a serious long-term and life-changing illness....
This is crucial at a time when single-target diagnostic assays are failing to detect natural mutants, putting those infected at risk of a se …
The Impact of Parental Incarceration on Psychopathy, Crime, and Prison Violence in Women.
Thomson ND, Moeller FG, Amstadter AB, Svikis D, Perera RA, Bjork JM. Thomson ND, et al. Int J Offender Ther Comp Criminol. 2020 Aug;64(10-11):1178-1194. doi: 10.1177/0306624X20904695. Epub 2020 Feb 10. Int J Offender Ther Comp Criminol. 2020. PMID: 32036722 Free PMC article.
There is a growing interest in understanding the consequences of parental incarceration. Unfortunately, research exploring the long-term criminological and personality effects in female offspring is limited, particularly among second-generation female offenders. ...
There is a growing interest in understanding the consequences of parental incarceration. Unfortunately, research exploring the long-term
Recent Developments In Bronchial Thermoplasty For Severe Asthma.
Thomson NC. Thomson NC. J Asthma Allergy. 2019 Nov 19;12:375-387. doi: 10.2147/JAA.S200912. eCollection 2019. J Asthma Allergy. 2019. PMID: 31819539 Free PMC article. Review.
Asthma morbidity increases during and shortly after treatment. Follow-up studies provide reassurance on the long-term safety of the procedure. Uncertainties remain about predictors of response, mechanism(s) of action, and place in management of severe asthma....
Asthma morbidity increases during and shortly after treatment. Follow-up studies provide reassurance on the long-term safety of the p …
Whole genome sequencing of toxigenic Clostridium difficile in asymptomatic carriers: insights into possible role in transmission.
Halstead FD, Ravi A, Thomson N, Nuur M, Hughes K, Brailey M, Oppenheim BA. Halstead FD, et al. Among authors: thomson n. J Hosp Infect. 2019 Jun;102(2):125-134. doi: 10.1016/j.jhin.2018.10.012. Epub 2018 Oct 22. J Hosp Infect. 2019. PMID: 30359648
BACKGROUND: Estimates of the prevalence of asymptomatically carried Clostridium difficile in elderly patients in long-term care range from 0% to 51%. Asymptomatic carriage is possibly a risk factor for the development of infection, and there is ongoing debate surrounding t …
BACKGROUND: Estimates of the prevalence of asymptomatically carried Clostridium difficile in elderly patients in long-term care range …
Realistic expectations for the treatment of FMGP residuals by chemical oxidants.
Shafieiyoun S, Thomson NR, Brey AP, Gasinski CM, Pence W, Marley M. Shafieiyoun S, et al. Among authors: thomson nr. J Contam Hydrol. 2018 Dec;219:1-17. doi: 10.1016/j.jconhyd.2018.08.007. Epub 2018 Sep 4. J Contam Hydrol. 2018. PMID: 30314848
To achieve a substantial degradation of mass within the treatment system (>40%), results from the screening model indicated that the hydraulic resident time would need to be >10 days and the average lumped mass transfer coefficient increased by two orders-of-magnitude. Resu …
To achieve a substantial degradation of mass within the treatment system (>40%), results from the screening model indicated that the hydr …
73 results