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The dose-response relationship of subretinal gene therapy with rAAV2tYF-CB-hRS1 in a mouse model of X-linked retinoschisis.
Hassan S, Hsu Y, Thompson JM, Kalmanek E, VandeLune JA, Stanley S, Drack AV. Hassan S, et al. Among authors: thompson jm. Front Med (Lausanne). 2024 Feb 13;11:1304819. doi: 10.3389/fmed.2024.1304819. eCollection 2024. Front Med (Lausanne). 2024. PMID: 38414621 Free PMC article.
We conducted a subretinal dose-response preclinical study using rAAV2tYF-CB-hRS1 utilizing the Rs1 knockout (Rs1-KO) mouse to investigate short- and long-term retinal rescue after subretinal gene delivery. METHODS: Rs1-KO mice were subretinally injected with 2 muL of rAAV2 …
We conducted a subretinal dose-response preclinical study using rAAV2tYF-CB-hRS1 utilizing the Rs1 knockout (Rs1-KO) mouse to investigate sh …
Maternal and neonatal morbidity associated with Fetal Pillow® use at full dilatation caesarean: A retrospective cohort.
Sadler LC, Thompson JMD, Alsweiler JM, McKinlay CJD, Cronin R, Browne E, Baillie-Bellew T, Harvey AD, Hill MG. Sadler LC, et al. Among authors: thompson jmd. BJOG. 2024 Jan 29. doi: 10.1111/1471-0528.17772. Online ahead of print. BJOG. 2024. PMID: 38287196
SETTING: Two tertiary maternity units, New Zealand. POPULATION OR SAMPLE: Full dilatation singleton, term, cephalic caesarean section, with three comparisons: at Unit A (1) before versus after introduction of the Fetal Pillow (1 Jaunary 2016-31 October 2021); (2) with vers …
SETTING: Two tertiary maternity units, New Zealand. POPULATION OR SAMPLE: Full dilatation singleton, term, cephalic caesarean section …
Neonatal and maternal outcomes at early vs. full term following induction of labor; A secondary analysis of the OBLIGE randomized trial.
Carlhäll S, Alsweiler J, Battin M, Wilson J, Sadler L, Thompson JMD, Wise MR. Carlhäll S, et al. Among authors: thompson jmd. Acta Obstet Gynecol Scand. 2024 May;103(5):955-964. doi: 10.1111/aogs.14775. Epub 2024 Jan 11. Acta Obstet Gynecol Scand. 2024. PMID: 38212889 Free PMC article. Clinical Trial.
INTRODUCTION: Birth at early term (37(+0)-38(+6) completed gestational weeks [GW] and additional days) is associated with adverse neonatal outcomes compared with waiting to 39 GW. ...Multivariable logistic regression was used to analyze neonatal and maternal outcome …
INTRODUCTION: Birth at early term (37(+0)-38(+6) completed gestational weeks [GW] and additional days) is associated with adve …
Factors associated with spontaneous vaginal birth in nulliparous women: A descriptive systematic review.
Kearney L, Nugent R, Maher J, Shipstone R, Thompson JM, Boulton R, George K, Robins A, Bogossian F. Kearney L, et al. Among authors: thompson jm. Women Birth. 2024 Feb;37(1):63-78. doi: 10.1016/j.wombi.2023.08.009. Epub 2023 Sep 12. Women Birth. 2024. PMID: 37704535 Free article. Review.
PROBLEM: Spontaneous vaginal birth (SVB) rates for nulliparous women are declining internationally. BACKGROUND: There is inadequate understanding of factors affecting this trend overall and limited large-scale responses to improve women's opportunity to birth sponta …
PROBLEM: Spontaneous vaginal birth (SVB) rates for nulliparous women are declining internationally. BACKGROUND: There is inadequate u …
Does fetal size affect maternal perception of fetal movements? Evidence from an individual participant data meta-analysis.
Thompson JMD, Heazell AEP, Cronin RS, Wilson J, Li M, Gordon A, Askie LM, O'Brien LM, Raynes-Greenow C, Stacey T, Mitchell EA, McCowan LME, Bradford BF. Thompson JMD, et al. Acta Obstet Gynecol Scand. 2023 Nov;102(11):1586-1592. doi: 10.1111/aogs.14652. Epub 2023 Aug 8. Acta Obstet Gynecol Scand. 2023. PMID: 37553853 Free PMC article.
INTRODUCTION: Maternal perception of fetal movements during pregnancy are reassuring; however, the perception of a reduction in movements are concerning to women and known to be associated with increased odds of late stillbirth. Prior to full term, little evidence exists t …
INTRODUCTION: Maternal perception of fetal movements during pregnancy are reassuring; however, the perception of a reduction in movements ar …
Outpatient balloon catheter vs inpatient prostaglandin for induction of labor: a randomized trial.
Wise MR, Thompson JMD, Battin M, McDougall J, Wilson J, Marriott J, Stitely M, Sadler L. Wise MR, et al. Among authors: thompson jmd. Am J Obstet Gynecol MFM. 2023 Jun;5(6):100958. doi: 10.1016/j.ajogmf.2023.100958. Epub 2023 Apr 6. Am J Obstet Gynecol MFM. 2023. PMID: 37028554 Clinical Trial.
The eligibility criteria were pregnant women (nullipara and multipara) with a live singleton fetus in vertex presentation with any medical comorbidity who underwent planned induction of labor at term and who had an initial modified Bishop Score of 0 to 6 at 1 of 11 public …
The eligibility criteria were pregnant women (nullipara and multipara) with a live singleton fetus in vertex presentation with any medical c …
Risk factors for late preterm and term stillbirth: A secondary analysis of an individual participant data meta-analysis.
Thompson RA, Thompson JMD, Wilson J, Cronin RS, Mitchell EA, Raynes-Greenow CH, Li M, Stacey T, Heazell AEP, O'Brien LM, McCowan LME, Anderson NH. Thompson RA, et al. Among authors: thompson jmd. BJOG. 2023 Aug;130(9):1060-1070. doi: 10.1111/1471-0528.17444. Epub 2023 Mar 21. BJOG. 2023. PMID: 36852504
OBJECTIVE: Identify independent and novel risk factors for late-preterm (28-36 weeks) and term (37 weeks) stillbirth and explore development of a risk-prediction model. ...CONCLUSIONS: Similarities in risk factors for late-preterm and term stillbirth suggest the sam …
OBJECTIVE: Identify independent and novel risk factors for late-preterm (28-36 weeks) and term (37 weeks) stillbirth and explore deve …
Subretinal gene therapy delays vision loss in a Bardet-Biedl Syndrome type 10 mouse model.
Hsu Y, Bhattarai S, Thompson JM, Mahoney A, Thomas J, Mayer SK, Datta P, Garrison J, Searby CC, Vandenberghe LH, Seo S, Sheffield VC, Drack AV. Hsu Y, et al. Among authors: thompson jm. Mol Ther Nucleic Acids. 2022 Dec 12;31:164-181. doi: 10.1016/j.omtn.2022.12.007. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2022. PMID: 36700052 Free PMC article.
In this study, we performed gene augmentation therapy by injecting a viral construct subretinally to deliver the coding sequence of the mouse Bbs10 gene to treat retinal degeneration in a BBS10 mouse model. Long-term efficacy was assessed by measuring the electrical functi …
In this study, we performed gene augmentation therapy by injecting a viral construct subretinally to deliver the coding sequence of the mous …
Effect of short-term hindlimb immobilization on skeletal muscle atrophy and the transcriptome in a low compared with high responder to endurance training model.
Thompson JM, West DWD, Doering TM, Budiono BP, Lessard SJ, Koch LG, Britton SL, Byrne NM, Brown MA, Ashton KJ, Coffey VG. Thompson JM, et al. PLoS One. 2022 Jan 13;17(1):e0261723. doi: 10.1371/journal.pone.0261723. eCollection 2022. PLoS One. 2022. PMID: 35025912 Free PMC article.
We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low responders to endurance training to identify biological processes associated with the early atrophy response. ...This indicates that geneti …
We compared changes in muscle mass and the transcriptome profile after short-term immobilization in a divergent model of high and low …
A better understanding of the association between maternal perception of foetal movements and late stillbirth-findings from an individual participant data meta-analysis.
Thompson JMD, Wilson J, Bradford BF, Li M, Cronin RS, Gordon A, Raynes-Greenow CH, Stacey T, Cullling VM, Askie LM, O'Brien LM, Mitchell EA, McCowan LME, Heazell AEP. Thompson JMD, et al. BMC Med. 2021 Nov 15;19(1):267. doi: 10.1186/s12916-021-02140-z. BMC Med. 2021. PMID: 34775977 Free PMC article.
A single episode of unusually vigorous movement was associated with increased odds (aOR = 2.86, 95% CI 2.01 to 4.07), which was higher in women at term. CONCLUSIONS: Reduced foetal movements are associated with late stillbirth, with the association strongest at preterm ges …
A single episode of unusually vigorous movement was associated with increased odds (aOR = 2.86, 95% CI 2.01 to 4.07), which was higher in wo …
56 results