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Matrix-free human pluripotent stem cell manufacturing by seed train approach and intermediate cryopreservation.
Ullmann K, Manstein F, Triebert W, Kriedemann N, Franke A, Teske J, Mertens M, Lupanow V, Göhring G, Haase A, Martin U, Zweigerdt R. Ullmann K, et al. Among authors: teske j. Stem Cell Res Ther. 2024 Mar 25;15(1):89. doi: 10.1186/s13287-024-03699-z. Stem Cell Res Ther. 2024. PMID: 38528578 Free PMC article.
The suspension culture (three-dimensional; 3D) of hPSCs in stirred tank bioreactors (STBRs) has enormous potential for fuelling these cell demands. In this study, the efficient long-term matrix-free suspension culture of hPSC aggregates is shown. ...
The suspension culture (three-dimensional; 3D) of hPSCs in stirred tank bioreactors (STBRs) has enormous potential for fuelling these cell d …
Myosin expression and contractile function are altered by replating stem cell-derived cardiomyocytes.
Osten F, Weber N, Wendland M, Holler T, Piep B, Kröhn S, Teske J, Bodenschatz AK, Devadas SB, Menge KS, Chatterjee S, Schwanke K, Kosanke M, Montag J, Thum T, Zweigerdt R, Kraft T, Iorga B, Meissner JD. Osten F, et al. Among authors: teske j. J Gen Physiol. 2023 Nov 6;155(11):e202313377. doi: 10.1085/jgp.202313377. Epub 2023 Sep 1. J Gen Physiol. 2023. PMID: 37656049 Free PMC article.
We previously demonstrated that 80% of human embryonic stem cell-derived cardiomyocytes (hESC-CMs) express exclusively beta-MyHC after long-term culture on laminin-coated glass coverslips. Here, we investigated the impact of enzymatically detaching hESC-CMs after long-t …
We previously demonstrated that 80% of human embryonic stem cell-derived cardiomyocytes (hESC-CMs) express exclusively beta-MyHC after long- …
Calcium-sensing receptor and CPAP-induced neonatal airway hyperreactivity in mice.
Mayer CA, Roos B, Teske J, Wells N, Martin RJ, Chang W, Pabelick CM, Prakash YS, MacFarlane PM. Mayer CA, et al. Among authors: teske j. Pediatr Res. 2022 May;91(6):1391-1398. doi: 10.1038/s41390-021-01540-4. Epub 2021 May 6. Pediatr Res. 2022. PMID: 33958714 Free PMC article.
BACKGROUND: Continuous positive airway pressure (CPAP) in preterm infants is initially beneficial, but animal models suggest longer term detrimental airway effects towards asthma. We used a neonatal CPAP mouse model and human fetal airway smooth muscle (ASM) to investigate …
BACKGROUND: Continuous positive airway pressure (CPAP) in preterm infants is initially beneficial, but animal models suggest longer term …
A candidate super-Earth planet orbiting near the snow line of Barnard's star.
Ribas I, Tuomi M, Reiners A, Butler RP, Morales JC, Perger M, Dreizler S, Rodríguez-López C, González Hernández JI, Rosich A, Feng F, Trifonov T, Vogt SS, Caballero JA, Hatzes A, Herrero E, Jeffers SV, Lafarga M, Murgas F, Nelson RP, Rodríguez E, Strachan JBP, Tal-Or L, Teske J, Toledo-Padrón B, Zechmeister M, Quirrenbach A, Amado PJ, Azzaro M, Béjar VJS, Barnes JR, Berdiñas ZM, Burt J, Coleman G, Cortés-Contreras M, Crane J, Engle SG, Guinan EF, Haswell CA, Henning T, Holden B, Jenkins J, Jones HRA, Kaminski A, Kiraga M, Kürster M, Lee MH, López-González MJ, Montes D, Morin J, Ofir A, Pallé E, Rebolo R, Reffert S, Schweitzer A, Seifert W, Shectman SA, Staab D, Street RA, Suárez Mascareño A, Tsapras Y, Wang SX, Anglada-Escudé G. Ribas I, et al. Among authors: teske j. Nature. 2018 Nov;563(7731):365-368. doi: 10.1038/s41586-018-0677-y. Epub 2018 Nov 14. Nature. 2018. PMID: 30429552
The combination of all radial-velocity datasets spanning 20 years of measurements additionally reveals a long-term modulation that could arise from a stellar magnetic-activity cycle or from a more distant planetary object. ...
The combination of all radial-velocity datasets spanning 20 years of measurements additionally reveals a long-term modulation that co …
Effects on Hedonic Feeding, Energy Expenditure and Balance of the Non-opioid Peptide DYN-A2-17.
Alvarez B, Barrientos T, Gac L, Teske JA, Perez-Leighton CE. Alvarez B, et al. Among authors: teske ja. Neuroscience. 2018 Feb 10;371:337-345. doi: 10.1016/j.neuroscience.2017.11.044. Epub 2017 Dec 2. Neuroscience. 2018. PMID: 29203229
Recent evidence shows that administering the non-opioid peptide DYN-A(2-17) into the paraventricular hypothalamic nucleus (PVN) simultaneously increased short-term intake of standard rodent chow and spontaneous physical activity (SPA). ...Injection of DYN-A(2-17) in PVN in …
Recent evidence shows that administering the non-opioid peptide DYN-A(2-17) into the paraventricular hypothalamic nucleus (PVN) simultaneous …
Long-term, intermittent, insulin-induced hypoglycemia produces marked obesity without hyperphagia or insulin resistance: a model for weight gain with intensive insulin therapy.
McNay EC, Teske JA, Kotz CM, Dunn-Meynell A, Levin BE, McCrimmon RJ, Sherwin RS. McNay EC, et al. Among authors: teske ja. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E131-8. doi: 10.1152/ajpendo.00262.2012. Epub 2012 Nov 20. Am J Physiol Endocrinol Metab. 2013. PMID: 23169787 Free PMC article.
Brain orexin promotes obesity resistance.
Kotz C, Nixon J, Butterick T, Perez-Leighton C, Teske J, Billington C. Kotz C, et al. Among authors: teske j. Ann N Y Acad Sci. 2012 Aug;1264(1):72-86. doi: 10.1111/j.1749-6632.2012.06585.x. Epub 2012 Jul 17. Ann N Y Acad Sci. 2012. PMID: 22803681 Free PMC article. Review.
Levels of energy intake and physical activity both contribute to body weight management, but it is challenging for most to adopt major long-term changes in either factor. Physical activity outside of formal exercise, also referred to as activity of daily living, and in str …
Levels of energy intake and physical activity both contribute to body weight management, but it is challenging for most to adopt major long- …
Spontaneous physical activity protects against fat mass gain.
Teske JA, Billington CJ, Kuskowski MA, Kotz CM. Teske JA, et al. Int J Obes (Lond). 2012 Apr;36(4):603-13. doi: 10.1038/ijo.2011.108. Epub 2011 May 24. Int J Obes (Lond). 2012. PMID: 21610695 Free PMC article.
OBJECTIVE: It is unclear whether elevated spontaneous physical activity (SPA, very low-intensity physical activity) positively influences body composition long term. We determined whether SPA and caloric intake were differentially related to the growth curve trajectories o …
OBJECTIVE: It is unclear whether elevated spontaneous physical activity (SPA, very low-intensity physical activity) positively influences bo …
Caloric restriction and physical activity in zebrafish (Danio rerio).
Novak CM, Jiang X, Wang C, Teske JA, Kotz CM, Levine JA. Novak CM, et al. Among authors: teske ja. Neurosci Lett. 2005 Jul 22-29;383(1-2):99-104. doi: 10.1016/j.neulet.2005.03.048. Epub 2005 Apr 20. Neurosci Lett. 2005. PMID: 15936519
Here, our goal was to test the hypothesis that fasting induces a biphasic pattern of change in PA by measuring PA before and after long-term food deprivation in zebrafish. Compared to control-fed fish, food-deprived fish showed a significant increase in PA levels during th …
Here, our goal was to test the hypothesis that fasting induces a biphasic pattern of change in PA by measuring PA before and after long-t …