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DNA Adduct Assessment During Antihormonal Treatment of Perianal Gland Tumors With Tamoxifen in Male Dogs.
Brodzki A, Tatara MR, Brodzki P, Balicki I. Brodzki A, et al. Among authors: tatara mr. In Vivo. 2019 May-Jun;33(3):731-735. doi: 10.21873/invivo.11532. In Vivo. 2019. PMID: 31028190 Free PMC article.
Six-month-long therapy with tamoxifen resulted in a significant increase in the DNA adduct count by 78.7%, 221.5% and 198.3% in the ADE, EPI and CAR groups, respectively (p<0.05). CONCLUSION: Increased DNA adduct formation after long-term administration of tamoxifen sho …
Six-month-long therapy with tamoxifen resulted in a significant increase in the DNA adduct count by 78.7%, 221.5% and 198.3% in the ADE, EPI …
Effects of long-term oral administration of methimazole on femur and tibia properties in male Wistar rats.
Tatara MR, Gołyński M, Radzki RP, Bieńko M, Krupski W. Tatara MR, et al. Biomed Pharmacother. 2017 Oct;94:124-128. doi: 10.1016/j.biopha.2017.07.107. Epub 2017 Jul 28. Biomed Pharmacother. 2017. PMID: 28759749
Methimazole (1-methyl-2-mercaptoimidazole) is an antithyroid drug used for the treatment of the hyperthyroidism in humans and animals. The aim of the study was to determine effects of long-term oral methimazole treatment in male Wistar rats on biochemical bone metabolism m …
Methimazole (1-methyl-2-mercaptoimidazole) is an antithyroid drug used for the treatment of the hyperthyroidism in humans and animals. The a …
Effects of combined maternal administration with alpha-ketoglutarate (AKG) and β-hydroxy-β-methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring.
Tatara MR, Krupski W, Tymczyna B, Studziński T. Tatara MR, et al. Nutr Metab (Lond). 2012 May 11;9(1):39. doi: 10.1186/1743-7075-9-39. Nutr Metab (Lond). 2012. PMID: 22578071 Free PMC article.
BACKGROUND: Nutritional manipulations during fetal growth may induce long-term metabolic effects in postnatal life. The aim of the study was to test whether combined treatment of pregnant sows with alpha-ketoglutarate and beta-hydroxy-beta-methylbutyrate induces additive l …
BACKGROUND: Nutritional manipulations during fetal growth may induce long-term metabolic effects in postnatal life. The aim of the st …
The long-term effect of alpha-ketoglutarate, given early in postnatal life, on both growth and various bone parameters in pigs.
Andersen NK, Tatara MR, Krupski W, Majcher P, Harrison AP. Andersen NK, et al. Among authors: tatara mr. J Anim Physiol Anim Nutr (Berl). 2008 Oct;92(5):519-28. doi: 10.1111/j.1439-0396.2007.00742.x. J Anim Physiol Anim Nutr (Berl). 2008. PMID: 19012595
The long-term effect of alpha-ketoglutarate (AKG) given for 21-24 days post-partum, on the skeleton of commercial pigs, was investigated. ...In addition, AKG elevated plasma 17 beta-oestradiol levels compared to those of controls at the end of the period of treatment (20%, …
The long-term effect of alpha-ketoglutarate (AKG) given for 21-24 days post-partum, on the skeleton of commercial pigs, was investiga …
Effect of β-hydroxy-β-methylbutyrate (HMB) administration on volumetric bone mineral density, and morphometric and mechanical properties of tibia in male turkeys.
Tatara MR. Tatara MR. J Anim Physiol Anim Nutr (Berl). 2009 Dec;93(6):669-77. doi: 10.1111/j.1439-0396.2008.00854.x. J Anim Physiol Anim Nutr (Berl). 2009. PMID: 18700848 Clinical Trial.
Cross-sectional area, second moment of inertia, maximum elastic strength and ultimate strength of tibia were significantly increased in HMB-treated turkeys by 21.3%, 49.0%, 27.2% and 28.3%, respectively (p 0.01). beta-hydroxy-beta-methylbutyrate administration increased plasma co …
Cross-sectional area, second moment of inertia, maximum elastic strength and ultimate strength of tibia were significantly increased in HMB- …
Neonatal programming of skeletal development in sheep is mediated by somatotrophic axis function.
Tatara MR. Tatara MR. Exp Physiol. 2008 Jun;93(6):763-72. doi: 10.1113/expphysiol.2007.041145. Epub 2008 Feb 8. Exp Physiol. 2008. PMID: 18263656 Free article.
Nutritional and metabolic exposure during critical periods of prenatal and neonatal development in animals and humans may induce long-term effects on health status in later life. The aim of this study was to investigate the effects of neonatal treatment with beta-hydroxy-b …
Nutritional and metabolic exposure during critical periods of prenatal and neonatal development in animals and humans may induce long-ter
Prenatal programming of skeletal development in the offspring: effects of maternal treatment with beta-hydroxy-beta-methylbutyrate (HMB) on femur properties in pigs at slaughter age.
Tatara MR, Sliwa E, Krupski W. Tatara MR, et al. Bone. 2007 Jun;40(6):1615-22. doi: 10.1016/j.bone.2007.02.018. Epub 2007 Mar 1. Bone. 2007. PMID: 17433802
Alteration in fetal growth and development in response to prenatal environmental conditions such as nutrition has long-term or permanent effects during postnatal life. The aim of this study was to investigate effects of beta-hydroxy-beta-methylbutyrate (HMB) treatment of s …
Alteration in fetal growth and development in response to prenatal environmental conditions such as nutrition has long-term or perman …
Long-term denervation of the humerus in turkeys as an experimental model for osteopenia.
Tatara MR, Krupski W, Majcher P, Studzinski T. Tatara MR, et al. Poult Sci. 2005 May;84(5):718-22. doi: 10.1093/ps/84.5.718. Poult Sci. 2005. PMID: 15913183 Free article.
The aim of this study was to evaluate the influence of long-term denervation on volumetric bone mineral density, and geometrical and mechanical properties of the humerus in turkeys. ...However, no significant differences between right and left humerus were observed when an …
The aim of this study was to evaluate the influence of long-term denervation on volumetric bone mineral density, and geometrical and …
Alpha-ketoglutarate treatment early in postnatal life improves bone density in lambs at slaughter.
Harrison AP, Tygesen MP, Sawa-Wojtanowicz B, Husted S, Tatara MR. Harrison AP, et al. Among authors: tatara mr. Bone. 2004 Jul;35(1):204-9. doi: 10.1016/j.bone.2004.03.016. Bone. 2004. PMID: 15207758
This study has investigated the long-term effect on skeletal development of a short postnatal period of oral alpha-ketoglutarate (AKG) administration, a compound known to regulate the synthesis of proline, which in turn is important for collagen production. ...
This study has investigated the long-term effect on skeletal development of a short postnatal period of oral alpha-ketoglutarate (AKG …