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An animal model for copper-associated cirrhosis in infancy.
Aston NS, Morris PA, Tanner MS, Variend S. Aston NS, et al. Among authors: tanner ms. J Pathol. 1998 Oct;186(2):215-21. doi: 10.1002/(SICI)1096-9896(1998100)186:2<215::AID-PATH145>3.0.CO;2-C. J Pathol. 1998. PMID: 9924439
Since copper administration alone has not been shown to induce cirrhosis in animals, synergy between copper and a second hepatotoxin has been suggested. This study investigates the ability of long-term exposure to copper and a pyrrolizidine alkaloid, retrorsine, to produce …
Since copper administration alone has not been shown to induce cirrhosis in animals, synergy between copper and a second hepatotoxin has bee …
Role of copper in Indian childhood cirrhosis.
Tanner MS. Tanner MS. Am J Clin Nutr. 1998 May;67(5 Suppl):1074S-1081S. doi: 10.1093/ajcn/67.5.1074S. Am J Clin Nutr. 1998. PMID: 9587155 Review.
Penicillamine, if given before the terminal clinical stage of ICC, reduces mortality from 92% to 53%. Long-term survivors show a sequence of histologic resolution, resulting either in inactive micronodular cirrhosis or in virtually normal histologic appearance. ...
Penicillamine, if given before the terminal clinical stage of ICC, reduces mortality from 92% to 53%. Long-term survivors show a sequ …