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Altered hepatic and intestinal homeostasis in a neonatal murine model of short-term total parenteral nutrition and antibiotics.
Mims TS, Kumari R, Leathem C, Antunes K, Joseph S, Yen MI, Ferstl D, Jamieson SM, Sabbar A, Biebel C, Lazarevic N, Willis NB, Henry L, Yen CE, Smith JP, Gosain A, Meisel M, Willis KA, Talati AJ, Elabiad MT, Hibl B, Pierre JF. Mims TS, et al. Among authors: talati aj. Am J Physiol Gastrointest Liver Physiol. 2023 Dec 1;325(6):G556-G569. doi: 10.1152/ajpgi.00129.2023. Epub 2023 Sep 27. Am J Physiol Gastrointest Liver Physiol. 2023. PMID: 37753583
We randomized mouse pups to PN or sham surgery controls +/- ABX exposure. ABX or short-term PN decreased liver and brain organ weights, intestinal length, and mucosal architecture (vs. controls). ...Within the gut, PN elevated the relative abundance of Akkermansia, Enteroc …
We randomized mouse pups to PN or sham surgery controls +/- ABX exposure. ABX or short-term PN decreased liver and brain organ weight …
Fungi form interkingdom microbial communities in the primordial human gut that develop with gestational age.
Willis KA, Purvis JH, Myers ED, Aziz MM, Karabayir I, Gomes CK, Peters BM, Akbilgic O, Talati AJ, Pierre JF. Willis KA, et al. Among authors: talati aj. FASEB J. 2019 Nov;33(11):12825-12837. doi: 10.1096/fj.201901436RR. Epub 2019 Aug 31. FASEB J. 2019. PMID: 31480903 Free PMC article. Clinical Trial.
To investigate primordial fungal ecology, we performed amplicon sequencing and culture-based techniques of first-pass meconium, which forms in the intestine prior to birth, from a prospective observational cohort of term and preterm newborns. Here, we describe funga …
To investigate primordial fungal ecology, we performed amplicon sequencing and culture-based techniques of first-pass meconium, which forms …
Neonates at risk for congenital syphilis: radiographic and cerebrospinal fluid evaluations.
Talati AJ, Koneru P. Talati AJ, et al. South Med J. 2011 Dec;104(12):827-30. doi: 10.1097/SMJ.0b013e31823875e9. South Med J. 2011. PMID: 22089362
Proper evaluation of neonates is important in preventing long-term consequences. The frequency of positive CSF and long bone radiography studies remains low. ...
Proper evaluation of neonates is important in preventing long-term consequences. The frequency of positive CSF and long bone radiogra …
In utero development of a warm-reactive autoantibody in a severely jaundiced neonate.
Blackall DP, Liles LH, Talati AJ. Blackall DP, et al. Among authors: talati aj. Transfusion. 2002 Jan;42(1):44-7. doi: 10.1046/j.1537-2995.2002.00016.x. Transfusion. 2002. PMID: 11896311
STUDY DESIGN AND METHODS: This report describes the case of a severely jaundiced full-term boy neonate presenting at birth with an IgG warm-reactive autoantibody. ...The serum also contained a panreactive antibody, and all crossmatches were incompatible. The neonate …
STUDY DESIGN AND METHODS: This report describes the case of a severely jaundiced full-term boy neonate presenting at birth wit …
Immunomodulation by exogenous surfactant: effect on TNF-alpha secretion and luminol-enhanced chemiluminescence activity by murine macrophages stimulated with group B streptococci.
Talati AJ, Crouse DT, English BK, Newman C, Harrison L, Meals E. Talati AJ, et al. Microbes Infect. 2001 Apr;3(4):267-73. doi: 10.1016/s1286-4579(01)01379-x. Microbes Infect. 2001. PMID: 11334743 Free article.
GBS stimulate alveolar macrophages to produce inflammatory cytokines and free oxygen radicals, which can damage the lungs. In several studies, use of exogenous surfactant in term babies has improved outcome related to sepsis and respiratory failure. ...
GBS stimulate alveolar macrophages to produce inflammatory cytokines and free oxygen radicals, which can damage the lungs. In several studie …
Persistent pulmonary hypertension after maternal naproxen ingestion in a term newborn: a case report.
Talati AJ, Salim MA, Korones SB. Talati AJ, et al. Am J Perinatol. 2000;17(2):69-71. doi: 10.1055/s-2000-9271. Am J Perinatol. 2000. PMID: 11023164
The fetal effects of other nonsteroid anti-inflammatory drugs (NSAIDs) like naproxen are not well reported. We report here a case of a 3,790-g term neonate who developed persistent pulmonary hypertension after birth with a closed ductus arteriosus. The mother admitt …
The fetal effects of other nonsteroid anti-inflammatory drugs (NSAIDs) like naproxen are not well reported. We report here a case of a 3,790 …