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Mononucleosis and antigen-driven T cell responses have different requirements for interleukin-2 signaling in murine gammaherpesvirus infection.
Molloy M, Zhang W, Usherwood E. Molloy M, et al. J Virol. 2010 Oct;84(20):10923-7. doi: 10.1128/JVI.00856-10. Epub 2010 Aug 4. J Virol. 2010. PMID: 20686022 Free PMC article.
Our study indicates that CD25 is necessary for optimal expansion of the antigen-specific CD8(+) T cell response but not for the long-term memory response. Contrastingly, IL-2 signaling through CD25 is absolutely required for CD8(+) T cell mononucleosis....
Our study indicates that CD25 is necessary for optimal expansion of the antigen-specific CD8(+) T cell response but not for the long-term …
The Pseudomonas aeruginosa magnesium transporter MgtE inhibits transcription of the type III secretion system.
Anderson GG, Yahr TL, Lovewell RR, O'Toole GA. Anderson GG, et al. Infect Immun. 2010 Mar;78(3):1239-49. doi: 10.1128/IAI.00865-09. Epub 2009 Dec 22. Infect Immun. 2010. PMID: 20028803 Free PMC article.
Pseudomonas aeruginosa is an opportunistic pathogen that causes life-long pneumonia in individuals with cystic fibrosis (CF). These long-term infections are maintained by bacterial biofilm formation in the CF lung. ...
Pseudomonas aeruginosa is an opportunistic pathogen that causes life-long pneumonia in individuals with cystic fibrosis (CF). These long- …