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2012 1
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2020 3
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Page 1
Real-World Clinical Practice Among Patients With Bipolar Disorder and Chronic Kidney Disease on Long-term Lithium Therapy.
Kumar R, Joseph B, Pazdernik VM, Geske J, Nuñez NA, Pahwa M, Kashani KB, Veldic M, Betcher HK, Moore KM, Croarkin PE, Ozerdem A, Cuellar-Barboza AB, McElroy SL, Biernacka JM, Frye MA, Singh B. Kumar R, et al. J Clin Psychopharmacol. 2023 Jan-Feb 01;43(1):6-11. doi: 10.1097/JCP.0000000000001632. J Clin Psychopharmacol. 2023. PMID: 36584244 Free PMC article.
PURPOSE: Long-term lithium therapy (LTLT) has been associated with chronic kidney disease (CKD). ...
PURPOSE: Long-term lithium therapy (LTLT) has been associated with chronic kidney disease (CKD). ...
Short Term Second-Generation Antidepressant Monotherapy in Acute Depressive Episodes of Bipolar II Disorder: A Systematic Review and Meta-Analysis.
Park JH, Nuñez NA, Gardea-Resendez M, Gerberi DJ, Breitinger S, Veldic M, Frye MA, Singh B. Park JH, et al. Psychopharmacol Bull. 2022 May 31;52(2):45-72. Psychopharmacol Bull. 2022. PMID: 35721812 Free PMC article. Review.
The discontinuation rate due to side-effects for SGAD monotherapy was significantly lower than lithium monotherapy with a RR = 0.32, 95% CI 0.11, 0.96, p = 0.04 but all-cause discontinuation rates were similar in both groups. CONCLUSIONS: Limited data suggests short-term e …
The discontinuation rate due to side-effects for SGAD monotherapy was significantly lower than lithium monotherapy with a RR = 0.32, 95% CI …
Subarachnoid hemorrhage rebleeding in the first 24 h is associated with external ventricular drain placement and higher grade on presentation: Cohort study.
Lu VM, Graffeo CS, Perry A, Carlstrom LP, Casabella AM, Wijdicks EFM, Lanzino G, Rabinstein AA. Lu VM, et al. J Clin Neurosci. 2020 Nov;81:180-185. doi: 10.1016/j.jocn.2020.09.064. Epub 2020 Oct 12. J Clin Neurosci. 2020. PMID: 33222913
EVD placement and higher SAH grade on presentation appear to be significantly and independently associated with increased risk of rebleeding within first 24 h, as well as unfavorable long-term functional outcome; however, the clinical benefit of hyper-acute aneurysm treatm …
EVD placement and higher SAH grade on presentation appear to be significantly and independently associated with increased risk of rebleeding …
Effects of Therapies on Cardiovascular Events in Ankylosing Spondylitis: A Systematic Review and Meta-Analysis.
Karmacharya P, Shahukhal R, Crowson CS, Murad MH, Davis JM 3rd, Shrestha P, Bekele D, Wright K, Chakradhar R, Dubreuil M. Karmacharya P, et al. Rheumatol Ther. 2020 Dec;7(4):993-1009. doi: 10.1007/s40744-020-00248-x. Epub 2020 Nov 10. Rheumatol Ther. 2020. PMID: 33170493 Free PMC article.
INTRODUCTION: Non-steroidal anti-inflammatory drugs (NSAIDs) and tumor necrosis factor inhibitors (TNFi) are the most common therapies used in AS, however, the associated long-term cardiovascular risk is unclear. We performed a systematic review and meta-analysis on the as …
INTRODUCTION: Non-steroidal anti-inflammatory drugs (NSAIDs) and tumor necrosis factor inhibitors (TNFi) are the most common therapies used …
Effect of Therapy on Radiographic Progression in Axial Spondyloarthritis: A Systematic Review and Meta-Analysis.
Karmacharya P, Duarte-Garcia A, Dubreuil M, Murad MH, Shahukhal R, Shrestha P, Myasoedova E, Crowson CS, Wright K, Davis JM 3rd. Karmacharya P, et al. Arthritis Rheumatol. 2020 May;72(5):733-749. doi: 10.1002/art.41206. Epub 2020 Apr 1. Arthritis Rheumatol. 2020. PMID: 31960614 Free PMC article.
CONCLUSION: Although no significant protective effect of TNFi treatment on spinal radiographic progression was seen over the course of 2 years or 4 years in patients with axial SpA, our analysis restricted to studies with a low risk of bias showed a protective effect of TNFi afte …
CONCLUSION: Although no significant protective effect of TNFi treatment on spinal radiographic progression was seen over the course of 2 yea …
DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine.
Yu J, Qin B, Moyer AM, Nowsheen S, Liu T, Qin S, Zhuang Y, Liu D, Lu SW, Kalari KR, Visscher DW, Copland JA, McLaughlin SA, Moreno-Aspitia A, Northfelt DW, Gray RJ, Lou Z, Suman VJ, Weinshilboum R, Boughey JC, Goetz MP, Wang L. Yu J, et al. J Clin Invest. 2018 Jun 1;128(6):2376-2388. doi: 10.1172/JCI97924. Epub 2018 Apr 30. J Clin Invest. 2018. PMID: 29708513 Free PMC article.
Furthermore, all 3 methytransferases, DNMT1, DNMT3A, and DNMT3B, were degraded following low-concentration, long-term decitabine treatment both in vitro and in vivo. The DNMT proteins could be ubiquitinated by the E3 ligase, TNF receptor-associated factor 6 (TRAF6), leadin …
Furthermore, all 3 methytransferases, DNMT1, DNMT3A, and DNMT3B, were degraded following low-concentration, long-term decitabine trea …
Electrophysiological Neuroimaging using sLORETA Comparing 12 Anorexia Nervosa Patients to 12 Controls.
Eugene AR, Masiak J, Kapica J. Eugene AR, et al. Brain (Bacau). 2014 Dec;5(1-4):26-33. Brain (Bacau). 2014. PMID: 26609424 Free PMC article.
The desired outcome would be for patients afflicted with AN to be diagnosed and treated at an earlier stage, increasing their overall long-term survival....
The desired outcome would be for patients afflicted with AN to be diagnosed and treated at an earlier stage, increasing their overall long- …
Effects of selective checkpoint kinase 1 inhibition on cytarabine cytotoxicity in acute myelogenous leukemia cells in vitro.
Schenk EL, Koh BD, Flatten KS, Peterson KL, Parry D, Hess AD, Smith BD, Karp JE, Karnitz LM, Kaufmann SH. Schenk EL, et al. Clin Cancer Res. 2012 Oct 1;18(19):5364-73. doi: 10.1158/1078-0432.CCR-12-0961. Epub 2012 Aug 6. Clin Cancer Res. 2012. PMID: 22869869 Free PMC article.
Human AML lines treated with cytarabine in the absence or presence of SCH 900776 were assayed for checkpoint activation by immunoblotting, nucleotide incorporation into DNA, and flow cytometry. Long-term effects in AML lines, clinical AML isolates, and normal myeloid proge …
Human AML lines treated with cytarabine in the absence or presence of SCH 900776 were assayed for checkpoint activation by immunoblotting, n …