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PMID: 27033548
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C1q is necessary for the toxic effects of soluble beta-amyloid (Abeta) oligomers on synapses and hippocampal long-term potentiation. Finally, microglia in adult brains engulf synaptic material in a CR3-dependent process when exposed to soluble Abeta oligomers. ...
C1q is necessary for the toxic effects of soluble beta-amyloid (Abeta) oligomers on synapses and hippocampal long-term potentiation. …