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Mitochondrial and metabolic remodelling in human skin fibroblasts in response to glucose availability.
Pinho SA, Costa CF, Deus CM, Pinho SLC, Miranda-Santos I, Afonso G, Bagshaw O, Stuart JA, Oliveira PJ, Cunha-Oliveira T. Pinho SA, et al. Among authors: stuart ja. FEBS J. 2022 Sep;289(17):5198-5217. doi: 10.1111/febs.16413. Epub 2022 Mar 7. FEBS J. 2022. PMID: 35213938 Free article.
LGm did not promote significant metabolic changes in NHDF, although mitochondrial network extension and VDAC protein content were increased compared to HGm-cultured cells. Our results indicate that short-term adaptation to OXPHOSm is ideal for studying mitochondrial health …
LGm did not promote significant metabolic changes in NHDF, although mitochondrial network extension and VDAC protein content were increased …
Quantification of Mitochondrial Network Characteristics in Health and Disease.
Valente AJ, Fonseca J, Moradi F, Foran G, Necakov A, Stuart JA. Valente AJ, et al. Among authors: stuart ja. Adv Exp Med Biol. 2019;1158:183-196. doi: 10.1007/978-981-13-8367-0_10. Adv Exp Med Biol. 2019. PMID: 31452141 Review.
The term 'mitochondrial dynamics' is commonly used to refer to ongoing fusion and fission of mitochondrial structures within a living cell. ...
The term 'mitochondrial dynamics' is commonly used to refer to ongoing fusion and fission of mitochondrial structures within a living …
A simple ImageJ macro tool for analyzing mitochondrial network morphology in mammalian cell culture.
Valente AJ, Maddalena LA, Robb EL, Moradi F, Stuart JA. Valente AJ, et al. Among authors: stuart ja. Acta Histochem. 2017 Apr;119(3):315-326. doi: 10.1016/j.acthis.2017.03.001. Epub 2017 Mar 15. Acta Histochem. 2017. PMID: 28314612
Mitochondria exist in a dynamic cycle of fusion and fission whose balance directly influences the morphology of the 'mitochondrial network', a term that encompasses the branched, reticular structure of fused mitochondria as well as the separate, punctate individual organel …
Mitochondria exist in a dynamic cycle of fusion and fission whose balance directly influences the morphology of the 'mitochondrial network', …
Folate deficiency increases mtDNA and D-1 mtDNA deletion in aged brain of mice lacking uracil-DNA glycosylase.
Kronenberg G, Gertz K, Overall RW, Harms C, Klein J, Page MM, Stuart JA, Endres M. Kronenberg G, et al. Among authors: stuart ja. Exp Neurol. 2011 Apr;228(2):253-8. doi: 10.1016/j.expneurol.2011.01.014. Epub 2011 Jan 28. Exp Neurol. 2011. PMID: 21281628
The rate of mitochondrial biogenesis as assessed at six weeks of the experimental diet by mRNA expression levels of transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha and of mitochondrial transcription factor A (Tfam) was not aff …
The rate of mitochondrial biogenesis as assessed at six weeks of the experimental diet by mRNA expression levels of transcriptional coactiva …
Photochemical and thermal stability of green and blue proteorhodopsins: implications for protein-based bioelectronic devices.
Ranaghan MJ, Shima S, Ramos L, Poulin DS, Whited G, Rajasekaran S, Stuart JA, Albert AD, Birge RR. Ranaghan MJ, et al. Among authors: stuart ja. J Phys Chem B. 2010 Nov 11;114(44):14064-70. doi: 10.1021/jp106633w. J Phys Chem B. 2010. PMID: 20964279 Free PMC article.
The lower cyclicity of BPR is found to be adequate for the long-term biological function of the host organism at ocean depths of 50 m or more....
The lower cyclicity of BPR is found to be adequate for the long-term biological function of the host organism at ocean depths of 50 m …
Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD.
Robb EL, Page MM, Wiens BE, Stuart JA. Robb EL, et al. Among authors: stuart ja. Biochem Biophys Res Commun. 2008 Mar 7;367(2):406-12. doi: 10.1016/j.bbrc.2007.12.138. Epub 2007 Dec 31. Biochem Biophys Res Commun. 2008. PMID: 18167310
trans-Resveratrol (3,4',5-trihydroxystilbene; RES), a polyphenol found in particularly high concentrations in red wine, has recently attracted intense interest for its potentially beneficial effects on human health. Here, we report the effects of long-term exposure to micr …
trans-Resveratrol (3,4',5-trihydroxystilbene; RES), a polyphenol found in particularly high concentrations in red wine, has recently attract …
Metabolic rate does not scale with body mass in cultured mammalian cells.
Brown MF, Gratton TP, Stuart JA. Brown MF, et al. Among authors: stuart ja. Am J Physiol Regul Integr Comp Physiol. 2007 Jun;292(6):R2115-21. doi: 10.1152/ajpregu.00568.2006. Epub 2007 Jan 18. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17234960 Free article.
To examine the effect of oxygen on steady-state cellular respiration rates, we grew cells under a variety of physiologically relevant oxygen regimens. Long-term exposure to higher medium oxygen levels increased respiration rates of all cells, consistent with the hypothesis …
To examine the effect of oxygen on steady-state cellular respiration rates, we grew cells under a variety of physiologically relevant oxygen …