Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

4 results

Filters applied: . Clear all
Page 1
Evidence for a role of plasma membrane calcium pumps in neurodegenerative disease: Recent developments.
Strehler EE, Thayer SA. Strehler EE, et al. Neurosci Lett. 2018 Jan 10;663:39-47. doi: 10.1016/j.neulet.2017.08.035. Epub 2017 Aug 19. Neurosci Lett. 2018. PMID: 28827127 Free PMC article. Review.
PMCA dysfunction is often poorly compensated in neurons and may lead to changes in synaptic transmission, altered excitability and, with long-term calcium overload, eventual cell death. Decrease and functional decline of PMCAs are hallmarks of neurodegeneration during agin …
PMCA dysfunction is often poorly compensated in neurons and may lead to changes in synaptic transmission, altered excitability and, with lon …
Emanuel Strehler's work on calcium pumps and calcium signaling.
Strehler EE. Strehler EE. World J Biol Chem. 2011 Apr 26;2(4):67-72. doi: 10.4331/wjbc.v2.i4.67. World J Biol Chem. 2011. PMID: 21537475 Free PMC article.
Accordingly, research in the Strehler laboratory is focused on a better understanding of the molecular "toolkit" needed to ensure proper Ca(2+) homeostasis in the cell, as well as on the mechanisms of localized Ca(2+) signaling. A long-term focus has been on the plasma mem …
Accordingly, research in the Strehler laboratory is focused on a better understanding of the molecular "toolkit" needed to ensure proper Ca( …
Rapid downregulation of NCX and PMCA in hippocampal neurons following H2O2 oxidative stress.
Kip SN, Strehler EE. Kip SN, et al. Among authors: strehler ee. Ann N Y Acad Sci. 2007 Mar;1099:436-9. doi: 10.1196/annals.1387.005. Ann N Y Acad Sci. 2007. PMID: 17446483 Free PMC article.
Elevated [Ca2+]i is a hallmark of neurodegenerative disease and stroke. Here we studied the short-term effect of oxidative stress on the plasma membrane Ca2+ extrusion systems in hippocampal neurons (HN) and found that after 2-3 h exposure to 300 microM H2O2, all NCXs and …
Elevated [Ca2+]i is a hallmark of neurodegenerative disease and stroke. Here we studied the short-term effect of oxidative stress on …
Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.
Strehler EE, Zacharias DA. Strehler EE, et al. Physiol Rev. 2001 Jan;81(1):21-50. doi: 10.1152/physrev.2001.81.1.21. Physiol Rev. 2001. PMID: 11152753 Free article. Review.
Together with Na(+)/Ca(2+) exchangers, they are the major plasma membrane transport system responsible for the long-term regulation of the resting intracellular Ca(2+) concentration. ...
Together with Na(+)/Ca(2+) exchangers, they are the major plasma membrane transport system responsible for the long-term regulation o …