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Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease.
Choate R, Holm KE, Sandhaus RA, Mannino DM, Strange C. Choate R, et al. Among authors: strange c. Int J Chron Obstruct Pulmon Dis. 2024 Apr 10;19:889-900. doi: 10.2147/COPD.S443183. eCollection 2024. Int J Chron Obstruct Pulmon Dis. 2024. PMID: 38617018 Free PMC article.
Age, mMRC categories, presence or absence of productive cough, frequency of exacerbations, and use of oxygen at baseline were significantly associated with the rate of change of SGRQ total (p<0.0001). CONCLUSION: We observed long-term stability in HRQoL and an associati …
Age, mMRC categories, presence or absence of productive cough, frequency of exacerbations, and use of oxygen at baseline were significantly …
A qualitative evaluation of a Young Parents Program (YPP) - Parent and facilitator perspectives.
Strange C, Bennett E, Tait M, Hauck Y. Strange C, et al. Health Promot J Austr. 2019 Sep;30(3):402-412. doi: 10.1002/hpja.228. Epub 2019 Feb 1. Health Promot J Austr. 2019. PMID: 30597660
ISSUE ADDRESSED: Young parents (<25 years) have lower engagement with health and community services and are more likely to experience negative outcomes in the perinatal period compared to older parents. The aim of this study was to evaluate the short to medium-term outc …
ISSUE ADDRESSED: Young parents (<25 years) have lower engagement with health and community services and are more likely to experience neg …
Short-term progression of interstitial lung disease in systemic sclerosis predicts long-term survival in two independent clinical trial cohorts.
Volkmann ER, Tashkin DP, Sim M, Li N, Goldmuntz E, Keyes-Elstein L, Pinckney A, Furst DE, Clements PJ, Khanna D, Steen V, Schraufnagel DE, Arami S, Hsu V, Roth MD, Elashoff RM, Sullivan KM; SLS I and SLS II study groups. Volkmann ER, et al. Ann Rheum Dis. 2019 Jan;78(1):122-130. doi: 10.1136/annrheumdis-2018-213708. Epub 2018 Nov 8. Ann Rheum Dis. 2019. PMID: 30409830 Free PMC article. Clinical Trial.
Counting process Cox proportional hazard modelling identified variables associated with long-term mortality in SLS I and II. Internal validation was performed using joint modelling. ...CONCLUSION: In addition to identifying traditional mortality risk factors in SSc (skin s …
Counting process Cox proportional hazard modelling identified variables associated with long-term mortality in SLS I and II. Internal …
Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial.
Sciurba FC, Criner GJ, Strange C, Shah PL, Michaud G, Connolly TA, Deslée G, Tillis WP, Delage A, Marquette CH, Krishna G, Kalhan R, Ferguson JS, Jantz M, Maldonado F, McKenna R, Majid A, Rai N, Gay S, Dransfield MT, Angel L, Maxfield R, Herth FJ, Wahidi MM, Mehta A, Slebos DJ; RENEW Study Research Group. Sciurba FC, et al. Among authors: strange c. JAMA. 2016 May 24-31;315(20):2178-89. doi: 10.1001/jama.2016.6261. JAMA. 2016. PMID: 27179849 Free article. Clinical Trial.
CONCLUSIONS AND RELEVANCE: Among patients with emphysema and severe hyperinflation treated for 12 months, the use of endobronchial coils compared with usual care resulted in an improvement in median exercise tolerance that was modest and of uncertain clinical importance, with a h …
CONCLUSIONS AND RELEVANCE: Among patients with emphysema and severe hyperinflation treated for 12 months, the use of endobronchial coils com …
Aclidinium bromide plus formoterol for the treatment of chronic obstructive pulmonary disease.
Lal C, Strange C. Lal C, et al. Among authors: strange c. Expert Opin Pharmacother. 2015 Feb;16(3):427-34. doi: 10.1517/14656566.2015.1000861. Expert Opin Pharmacother. 2015. PMID: 25597386 Review.
EXPERT OPINION: Initial data for the aclidinium/formoterol inhaler appears to be promising for impacting the lung function. To define if this benefit translates into improved long-term outcomes of decreased exacerbation frequency, improved quality of life and decreased dis …
EXPERT OPINION: Initial data for the aclidinium/formoterol inhaler appears to be promising for impacting the lung function. To define if thi …
Sitaxsentan for the treatment of pulmonary arterial hypertension: a 1-year, prospective, open-label observation of outcome and survival.
Benza RL, Barst RJ, Galie N, Frost A, Girgis RE, Highland KB, Strange C, Black CM, Badesch DB, Rubin L, Fleming TR, Naeije R. Benza RL, et al. Among authors: strange c. Chest. 2008 Oct;134(4):775-782. doi: 10.1378/chest.07-0767. Epub 2008 Jul 14. Chest. 2008. PMID: 18625676 Clinical Trial.
BACKGROUND: Despite advances in the management of pulmonary arterial hypertension (PAH), the mortality rate remains excessive. Long-term efficacy evaluations are needed to guide therapeutic management. ...
BACKGROUND: Despite advances in the management of pulmonary arterial hypertension (PAH), the mortality rate remains excessive. Long-term …
"The lion, the witch and the wardrobe": impact on sibs of individuals with AAT deficiency.
Fanos JH, Strange C. Fanos JH, et al. Among authors: strange c. Am J Med Genet A. 2004 Oct 15;130A(3):251-7. doi: 10.1002/ajmg.a.30255. Am J Med Genet A. 2004. PMID: 15378547
Respondents were supportive of testing prior to adulthood for AAT status; 18 thought it was a good idea to test a child, three did not know, and four said children should not be tested, primarily citing insurance concerns. Of those 18 who stated it was a good idea, 14 would test …
Respondents were supportive of testing prior to adulthood for AAT status; 18 thought it was a good idea to test a child, three did not know, …
Long-term effects of inhaled corticosteroids on FEV1 in patients with chronic obstructive pulmonary disease. A meta-analysis.
Highland KB, Strange C, Heffner JE. Highland KB, et al. Among authors: strange c. Ann Intern Med. 2003 Jun 17;138(12):969-73. doi: 10.7326/0003-4819-138-12-200306170-00008. Ann Intern Med. 2003. PMID: 12809453
BACKGROUND: There is no consensus on the effectiveness of inhaled corticosteroids for the treatment of chronic obstructive pulmonary disease (COPD). PURPOSE: To evaluate the long-term effects of inhaled corticosteroids on the rate of FEV1 decline in patients with COPD. ...
BACKGROUND: There is no consensus on the effectiveness of inhaled corticosteroids for the treatment of chronic obstructive pulmonary disease …
Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension.
Strange C, Bolster M, Mazur J, Taylor M, Gossage JR, Silver R. Strange C, et al. Chest. 2000 Oct;118(4):1077-82. doi: 10.1378/chest.118.4.1077. Chest. 2000. PMID: 11035680
CONCLUSION: SSc patients with ILD have diverse and sometimes multiple causes of PH that can be determined by short-term epoprostenol infusion. Beneficial effects can be obtained from epoprostenol despite extensive ILD....
CONCLUSION: SSc patients with ILD have diverse and sometimes multiple causes of PH that can be determined by short-term epoprostenol …