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Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design.
Gross RS, Thaweethai T, Rosenzweig EB, Chan J, Chibnik LB, Cicek MS, Elliott AJ, Flaherman VJ, Foulkes AS, Gage Witvliet M, Gallagher R, Gennaro ML, Jernigan TL, Karlson EW, Katz SD, Kinser PA, Kleinman LC, Lamendola-Essel MF, Milner JD, Mohandas S, Mudumbi PC, Newburger JW, Rhee KE, Salisbury AL, Snowden JN, Stein CR, Stockwell MS, Tantisira KG, Thomason ME, Truong DT, Warburton D, Wood JC, Ahmed S, Akerlundh A, Alshawabkeh AN, Anderson BR, Aschner JL, Atz AM, Aupperle RL, Baker FC, Balaraman V, Banerjee D, Barch DM, Baskin-Sommers A, Bhuiyan S, Bind MC, Bogie AL, Bradford T, Buchbinder NC, Bueler E, Bükülmez H, Casey BJ, Chang L, Chrisant M, Clark DB, Clifton RG, Clouser KN, Cottrell L, Cowan K, D'Sa V, Dapretto M, Dasgupta S, Dehority W, Dionne A, Dummer KB, Elias MD, Esquenazi-Karonika S, Evans DN, Faustino EVS, Fiks AG, Forsha D, Foxe JJ, Friedman NP, Fry G, Gaur S, Gee DG, Gray KM, Handler S, Harahsheh AS, Hasbani K, Heath AC, Hebson C, Heitzeg MM, Hester CM, Hill S, Hobart-Porter L, Hong TKF, Horowitz CR, Hsia DS, Huentelman M, Hummel KD, Irby K, Jacobus J, Jacoby VL, Jone PN, Kaelber DC, Kasmarcak TJ, Kluko MJ, Kosut JS, Laird AR, Landeo-Gutierrez J, Lang SM, Larson CL, Li… See abstract for full author list ➔ Gross RS, et al. Among authors: stevenson md. PLoS One. 2024 May 7;19(5):e0285635. doi: 10.1371/journal.pone.0285635. eCollection 2024. PLoS One. 2024. PMID: 38713673 Free PMC article.
IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long COVID") in children and young adults remain unknown. ...CONCLUSIONS AND RELEVANCE: RECOVER-Pediatrics seeks to characterize the clinical cours …
IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long CO …
Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation.
Abhishek A, Grainge M, Card T, Williams HC, Taal MW, Aithal GP, Fox CP, Mallen CD, Stevenson MD, Nakafero G, Riley R. Abhishek A, et al. Among authors: stevenson md. RMD Open. 2024 Mar 7;10(1):e003980. doi: 10.1136/rmdopen-2023-003980. RMD Open. 2024. PMID: 38453215 Free PMC article.
BACKGROUND: Sulfasalazine-induced cytopenia, nephrotoxicity and hepatotoxicity is uncommon during long-term treatment. Some guidelines recommend 3 monthly monitoring blood tests indefinitely during long-term treatment while others recommend stopping monitoring after …
BACKGROUND: Sulfasalazine-induced cytopenia, nephrotoxicity and hepatotoxicity is uncommon during long-term treatment. Some guideline …
Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation.
Nakafero G, Card T, Grainge MJ, Williams HC, Taal MW, Aithal GP, Fox CP, Mallen CD, van der Windt DA, Stevenson MD, Riley RD, Abhishek A. Nakafero G, et al. Among authors: stevenson md. EClinicalMedicine. 2023 Sep 14;64:102213. doi: 10.1016/j.eclinm.2023.102213. eCollection 2023 Oct. EClinicalMedicine. 2023. PMID: 37745026 Free PMC article.
., azathioprine) are recommended to undergo three-monthly blood tests for the early detection of blood, liver, or kidney toxicity. These side-effects are uncommon during long-term treatment. We developed a prognostic model that could be used to inform risk-stratified decis …
., azathioprine) are recommended to undergo three-monthly blood tests for the early detection of blood, liver, or kidney toxicity. These sid …
Risk stratified monitoring for methotrexate toxicity in immune mediated inflammatory diseases: prognostic model development and validation using primary care data from the UK.
Nakafero G, Grainge MJ, Williams HC, Card T, Taal MW, Aithal GP, Fox CP, Mallen CD, van der Windt DA, Stevenson MD, Riley RD, Abhishek A. Nakafero G, et al. Among authors: stevenson md. BMJ. 2023 May 30;381:e074678. doi: 10.1136/bmj-2022-074678. BMJ. 2023. PMID: 37253479 Free PMC article.
OBJECTIVE: To develop and validate a prognostic model to inform risk stratified decisions on frequency of monitoring blood tests during long term methotrexate treatment. DESIGN: Retrospective cohort study. ...CONCLUSION: A prognostic model was developed and validated that …
OBJECTIVE: To develop and validate a prognostic model to inform risk stratified decisions on frequency of monitoring blood tests during long …
Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design.
Gross R, Thaweethai T, Rosenzweig EB, Chan J, Chibnik LB, Cicek MS, Elliott AJ, Flaherman VJ, Foulkes AS, Witvliet MG, Gallagher R, Gennaro ML, Jernigan TL, Karlson EW, Katz SD, Kinser PA, Kleinman LC, Lamendola-Essel MF, Milner JD, Mohandas S, Mudumbi PC, Newburger JW, Rhee KE, Salisbury AL, Snowden JN, Stein CR, Stockwell MS, Tantisira KG, Thomason ME, Truong DT, Warburton D, Wood JC, Ahmed S, Akerlundh A, Alshawabkeh AN, Anderson BR, Aschner JL, Atz AM, Aupperle RL, Baker FC, Balaraman V, Banerjee D, Barch DM, Baskin-Sommers A, Bhuiyan S, Bind MC, Bogie AL, Buchbinder NC, Bueler E, Bükülmez H, Casey BJ, Chang L, Clark DB, Clifton RG, Clouser KN, Cottrell L, Cowan K, D'Sa V, Dapretto M, Dasgupta S, Dehority W, Dummer KB, Elias MD, Esquenazi-Karonika S, Evans DN, Faustino EVS, Fiks AG, Forsha D, Foxe JJ, Friedman NP, Fry G, Gaur S, Gee DG, Gray KM, Harahsheh AS, Heath AC, Heitzeg MM, Hester CM, Hill S, Hobart-Porter L, Hong TKF, Horowitz CR, Hsia DS, Huentelman M, Hummel KD, Iacono WG, Irby K, Jacobus J, Jacoby VL, Jone PN, Kaelber DC, Kasmarcak TJ, Kluko MJ, Kosut JS, Laird AR, Landeo-Gutierrez J, Lang SM, Larson CL, Lim PPC, Lisdahl KM, McCrindle BW, McCulloh RJ, Mendelsohn AL,… See abstract for full author list ➔ Gross R, et al. Among authors: stevenson md. medRxiv [Preprint]. 2023 May 12:2023.04.27.23289228. doi: 10.1101/2023.04.27.23289228. medRxiv. 2023. PMID: 37214806 Free PMC article. Updated. Preprint.
IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long COVID") in children and young adults remain unknown. ...CONCLUSIONS AND RELEVANCE: RECOVER-Pediatrics seeks to characterize the clinical cours …
IMPORTANCE: The prevalence, pathophysiology, and long-term outcomes of COVID-19 (post-acute sequelae of SARS-CoV-2 [PASC] or "Long CO …
Health Care Utilization During the COVID-19 Pandemic Among Individuals Born Preterm.
McGowan EC, McGrath M, Law A, O'Shea TM, Aschner JL, Blackwell CK, Fry RC, Ganiban JM, Higgins R, Margolis A, Sathyanarayana S, Taylor G, Alshawabkeh AN, Cordero JF, Spillane NT, Hudak ML, Camargo CA Jr, Dabelea D, Dunlop AL, Elliott AJ, Ferrara AM, Talavera-Barber M, Singh AM, Karagas MR, Karr C, O'Connor TG, Paneth N, Wright RJ, Wright RO, Cowell W, Stanford JB, Bendixsen C, Lester BM; program collaborators for Environmental Influences on Child Health Outcomes (ECHO). McGowan EC, et al. JAMA Netw Open. 2023 Apr 3;6(4):e2310696. doi: 10.1001/jamanetworkopen.2023.10696. JAMA Netw Open. 2023. PMID: 37115545 Free PMC article.
Individuals born preterm vs term (37 weeks' gestation) and differences among preterm subgroups of individuals (<28 weeks', 28-36 weeks' vs 37 weeks' gestation) were assessed. ...RESULTS: Data from 1691 children and young adults were analyzed; among 270 individuals born …
Individuals born preterm vs term (37 weeks' gestation) and differences among preterm subgroups of individuals (<28 weeks', 28-36 w …
The Cost-Effectiveness of Belimumab and Voclosporin for Patients with Lupus Nephritis in the United States.
Mandrik O, Fotheringham J, Ren S, Tice JA, Chapman RH, Stevenson MD, Pearson SD, Herron-Smith S, Agboola F, Thokala P. Mandrik O, et al. Among authors: stevenson md. Clin J Am Soc Nephrol. 2022 Mar;17(3):385-394. doi: 10.2215/CJN.13030921. Epub 2022 Feb 3. Clin J Am Soc Nephrol. 2022. PMID: 35115304 Free PMC article.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A de novo economic model was developed to estimate the cost-effectiveness of these therapies, including the following health states: "complete response," "partial response," and "active disease" defined by eGFR and proteinuria ch …
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A de novo economic model was developed to estimate the cost-effectiveness of these therap …
Comparing current and emerging practice models for the extrapolation of survival data: a simulation study and case-study.
Kearns B, Stevenson MD, Triantafyllopoulos K, Manca A. Kearns B, et al. Among authors: stevenson md. BMC Med Res Methodol. 2021 Nov 27;21(1):263. doi: 10.1186/s12874-021-01460-1. BMC Med Res Methodol. 2021. PMID: 34837957 Free PMC article.
The simulation study used a mixture-Weibull model as the data-generating mechanism with varying lengths of follow-up and sample sizes. The case-study was long-term follow-up of a prostate cancer trial. For both studies, models were fit to an early data-cut of the data, and …
The simulation study used a mixture-Weibull model as the data-generating mechanism with varying lengths of follow-up and sample sizes. The c …
Modeling the Economic Impact of Interventions for Older Populations with Multimorbidity: A Method of Linking Multiple Single-Disease Models.
Youn JH, Stevenson MD, Thokala P, Payne K, Goddard M. Youn JH, et al. Among authors: stevenson md. Med Decis Making. 2019 Oct;39(7):842-856. doi: 10.1177/0272989X19868987. Epub 2019 Aug 20. Med Decis Making. 2019. PMID: 31431188 Free article.
It also has potential for wider applications in informing decisions on commissioning of health care services and long-term priority setting across diseases and health care programs through providing potentially more accurate estimations of the relative cost-effectiveness o …
It also has potential for wider applications in informing decisions on commissioning of health care services and long-term priority s …
Scholarly Collaboration, Mentorship, and Friendship: A New Model for Success in Academic Medicine.
Abramson EL, Naifeh MM, Stevenson MD, Li ST. Abramson EL, et al. Among authors: stevenson md. Acad Pediatr. 2019 Nov-Dec;19(8):860-864. doi: 10.1016/j.acap.2019.07.010. Epub 2019 Aug 2. Acad Pediatr. 2019. PMID: 31382043
Our model aims to promote longitudinal, collaborative scholarship around a broad common research theme, provide long-term mentorship focused on successfully navigating personal and academic hurdles, and create a forum of mentorship for faculty at all academic ranks. ...
Our model aims to promote longitudinal, collaborative scholarship around a broad common research theme, provide long-term mentorship …
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