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Anti-interferon antibodies to interferon-alpha 2b: results of comparative assays and clinical perspective.
Spiegel RJ, Jacobs SL, Treuhaft MW. Spiegel RJ, et al. J Interferon Res. 1989 Sep;9 Suppl 1:S17-24. J Interferon Res. 1989. PMID: 2553829
In this report two patient groups, 151 hairy cell leukemia (HCL) patients and 101 patients with other malignancies, who have received long-term dosing with IFN-alpha 2b, are reported. The sera of both groups were studied before, during and after treatment by various assay …
In this report two patient groups, 151 hairy cell leukemia (HCL) patients and 101 patients with other malignancies, who have received long- …
Combined recombinant human interferon alpha 2 and cytotoxic agents studied in a clonogenic assay.
Welander CE, Morgan TM, Homesley HD, Trotta PP, Spiegel RJ. Welander CE, et al. Among authors: spiegel rj. Int J Cancer. 1985 Jun 15;35(6):721-9. doi: 10.1002/ijc.2910350605. Int J Cancer. 1985. PMID: 4008100
Results show that interferon as a single agent causes insignificant reduction in tumor cell colony survival if the short-term 1-hr cell exposure method is used; only high concentrations of interferon used in continuous cell exposure in the clonogenic assay can demonstrate …
Results show that interferon as a single agent causes insignificant reduction in tumor cell colony survival if the short-term 1-hr ce …
Adrenal suppression after short-term corticosteroid therapy.
Spiegel RJ, Vigersky RA, Oliff AI, Echelberger CK, Bruton J, Poplack DG. Spiegel RJ, et al. Lancet. 1979 Mar 24;1(8117):630-3. doi: 10.1016/s0140-6736(79)91077-8. Lancet. 1979. PMID: 85870
Adrenal function was evaluated in fourteen cancer patients receiving chemotherapy which included short-term high-dose courses of prednisone. 90 min corticotropin stimulation tests were performed before therapy and 1, 2, 4, and 7 days after steroids were discontinued. ...Al …
Adrenal function was evaluated in fourteen cancer patients receiving chemotherapy which included short-term high-dose courses of pred …