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Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine β-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial.
Van Hove JLK, Freehauf CL, Ficicioglu C, Pena LDM, Moreau KL, Henthorn TK, Christians U, Jiang H, Cowan TM, Young SP, Hite M, Friederich MW, Stabler SP, Spector EB, Kronquist KE, Thomas JA, Emmett P, Harrington MJ, Pyle L, Creadon-Swindell G, Wempe MF, MacLean KN. Van Hove JLK, et al. Among authors: spector eb. J Inherit Metab Dis. 2019 May;42(3):424-437. doi: 10.1002/jimd.12085. Epub 2019 Apr 11. J Inherit Metab Dis. 2019. PMID: 30873612 Clinical Trial.
STUDY OBJECTIVE: A phase 1/2 clinical trial was performed in individuals with cystathionine beta synthase (CBS) deficient homocystinuria with aims to: (a) assess pharmacokinetics and safety of taurine therapy, (b) evaluate oxidative stress, inflammation, and vascular function in …
STUDY OBJECTIVE: A phase 1/2 clinical trial was performed in individuals with cystathionine beta synthase (CBS) deficient homocystinuria wit …
Further delineation of achondroplasia-hypochondroplasia complex with long-term survival.
González-Del Angel A, Rius R, Alcántara-Ortigoza MA, Spector E, Del Castillo V, Mata-García LE. González-Del Angel A, et al. Among authors: spector e. Am J Med Genet A. 2018 May;176(5):1225-1231. doi: 10.1002/ajmg.a.38660. Am J Med Genet A. 2018. PMID: 29681095 Review.
This patient exhibits intellectual disability, has a history of seizures, experienced multiple cardiorespiratory complications during early childhood, and required foramen magnum decompression. However, he now shows a stable health condition with long-term survival (curren …
This patient exhibits intellectual disability, has a history of seizures, experienced multiple cardiorespiratory complications during early …
Risk factors for metachronous adenoma in the residual colon of patients undergoing curative surgery for colorectal cancer.
Patel A, Williams N, Parsons N, Ali O, Peters F, Ranat R, Shah J, Spector E, Arasaradnam RP. Patel A, et al. Among authors: spector e. Int J Colorectal Dis. 2017 Nov;32(11):1609-1616. doi: 10.1007/s00384-017-2881-x. Epub 2017 Aug 21. Int J Colorectal Dis. 2017. PMID: 28828520 Free PMC article.
Men and those undergoing right-sided resection have a higher risk of metachronous adenoma in the long term and may benefit from more frequent endoscopic surveillance post resection....
Men and those undergoing right-sided resection have a higher risk of metachronous adenoma in the long term and may benefit from more …
Evaluating Bone Loss in ISS Astronauts.
Sibonga JD, Spector ER, Johnston SL, Tarver WJ. Sibonga JD, et al. Among authors: spector er. Aerosp Med Hum Perform. 2015 Dec;86(12 Suppl):A38-A44. doi: 10.3357/AMHP.EC06.2015. Aerosp Med Hum Perform. 2015. PMID: 26630194
Consequently, use of relatively new research technologies is being proposed to NASA for risk surveillance and to enhance long-term management of skeletal health in long-duration astronauts. Sibonga JD, Spector ER, Johnston SL, Tarver WJ. ...
Consequently, use of relatively new research technologies is being proposed to NASA for risk surveillance and to enhance long-term ma …
DNA diagnosis and management of Hermansky-Pudlak syndrome in pregnancy.
Wax JR, Rosengren S, Spector E, Gainey AJ, Ingardia CJ. Wax JR, et al. Among authors: spector e. Am J Perinatol. 2001 May;18(3):159-61. doi: 10.1055/s-2001-14528. Am J Perinatol. 2001. PMID: 11414528
An 18-year-old primigravida with OCA was diagnosed during pregnancy with Hermansky-Pudlak syndrome by DNA analysis. Uneventful vaginal delivery occurred at term following prophylactic platelet transfusion. Women of northwestern Puerto Rican descent with OCA should be offer …
An 18-year-old primigravida with OCA was diagnosed during pregnancy with Hermansky-Pudlak syndrome by DNA analysis. Uneventful vaginal deliv …
Hologic QDR 2000 whole-body scans: a comparison of three combinations of scan modes and analysis software.
Spector E, LeBlanc A, Shackelford L. Spector E, et al. Osteoporos Int. 1995;5(6):440-5. doi: 10.1007/BF01626605. Osteoporos Int. 1995. PMID: 8695965
This study reports on the short-term in vivo precision and absolute measurements of three combinations of whole-body scan modes and analysis software using a Hologic QDR 2000 dual-energy X-ray densitometer. ...In general, there was no significant difference among the three …
This study reports on the short-term in vivo precision and absolute measurements of three combinations of whole-body scan modes and a …
Zinc and copper balances in healthy adult males during and after 17 wk of bed rest.
Krebs JM, Schneider VS, LeBlanc AD, Kuo MC, Spector E, Lane HW. Krebs JM, et al. Among authors: spector e. Am J Clin Nutr. 1993 Dec;58(6):897-901. doi: 10.1093/ajcn/58.6.897. Am J Clin Nutr. 1993. PMID: 8249875
The effects of long-term bed rest on zinc and copper balances were measured in seven healthy men. ...Reambulation decreased fecal zinc excretion and increased both zinc and copper balances. These results suggest that during long-term bed rest or space flight, indivi …
The effects of long-term bed rest on zinc and copper balances were measured in seven healthy men. ...Reambulation decreased fecal zin …
14 results