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Influence of Eat, Sleep, and Console on Infants Pharmacologically Treated for Opioid Withdrawal: A Post Hoc Subgroup Analysis of the ESC-NOW Randomized Clinical Trial.
Devlin LA, Hu Z, Merhar SL, Ounpraseuth ST, Simon AE, Lee JY, Das A, Crawford MM, Greenberg RG, Smith PB, Higgins RD, Walsh MC, Rice W, Paul DA, Maxwell JR, Fung CM, Wright T, Ross J, McAllister JM, Crowley M, Shaikh SK, Christ L, Brown J, Riccio J, Wong Ramsey K, Braswell EF, Tucker L, McAlmon K, Dummula K, Weiner J, White JR, Newman S, Snowden JN, Young LW; Eunice Kennedy Shriver NICHD Neonatal Research Network and NIH Environmental Influences on Child Health Outcomes (ECHO) Program Institutional Development Award States Pediatric Clinical Trials Network. Devlin LA, et al. JAMA Pediatr. 2024 Apr 15:e240544. doi: 10.1001/jamapediatrics.2024.0544. Online ahead of print. JAMA Pediatr. 2024. PMID: 38619854 Free PMC article.
MAIN OUTCOMES AND MEASURES: For each outcome (total opioid exposure, peak opioid dose, time from birth to initiation of first opioid dose, length of opioid treatment, and LOS), we used generalized linear mixed models to adjust for the stepped-wedge design and maternal and …
MAIN OUTCOMES AND MEASURES: For each outcome (total opioid exposure, peak opioid dose, time from birth to initiation of first opioid …
TRPM2 and CaMKII signaling drives excessive GABAergic synaptic inhibition following ischemia.
Burch AM, Garcia JD, O'Leary H, Haas A, Orfila JE, Tiemeier E, Chalmers N, Smith KR, Quillinan N, Herson PS. Burch AM, et al. Among authors: smith kr. J Neurosci. 2024 Apr 2:e1762232024. doi: 10.1523/JNEUROSCI.1762-23.2024. Online ahead of print. J Neurosci. 2024. PMID: 38565288
We previously demonstrated sustained impairment of long-term potentiation (LTP) in hippocampal CA1 neurons correlating with deficits in learning and memory tasks in a murine model of cardiac arrest/ cardiopulmonary resuscitation (CA/CPR). ...Previous studies indicated isch …
We previously demonstrated sustained impairment of long-term potentiation (LTP) in hippocampal CA1 neurons correlating with deficits …
Mortality risk following end-of-life caregiving: A population-based analysis of hospice users and their families.
Hollingshaus M, Smith KR, Meeks H, Ornstein K, Iacob E, Tay D, Stephens C, Utz RL. Hollingshaus M, et al. Among authors: smith kr. Soc Sci Med. 2024 May;348:116781. doi: 10.1016/j.socscimed.2024.116781. Epub 2024 Mar 16. Soc Sci Med. 2024. PMID: 38547806
Adopting a linked-lived theoretical perspective, exposure to the death and dying of one family member could be conceptualized as a significant life stressor that produces short and long-term health consequences for surviving family members. This study uses familial-linked …
Adopting a linked-lived theoretical perspective, exposure to the death and dying of one family member could be conceptualized as a significa …
Extent of investigation and management of cases of 'unexplained' mismatch repair deficiency (u-dMMR): a UK Cancer Genetics Group consensus.
McVeigh TP, Monahan KJ, Christopher J, West N, Scott M, Murray J, Hanson H; UKCGG dMMR Consensus Meeting Attendees. McVeigh TP, et al. J Med Genet. 2024 Apr 6:jmg-2024-109886. doi: 10.1136/jmg-2024-109886. Online ahead of print. J Med Genet. 2024. PMID: 38531626
However, in most cases, it results from sporadic somatic events rather than hereditary factors. The term 'Lynch-like syndrome' (LLS) has been used to guide colorectal cancer surveillance for relatives of individuals with a dMMR tumour when somatic and germline genomic test …
However, in most cases, it results from sporadic somatic events rather than hereditary factors. The term 'Lynch-like syndrome' (LLS) …
Prevalence of Distal Symmetrical Polyneuropathy by Diabetes Prevention Program Treatment Group, Diabetes Status, Duration of Diabetes, and Cumulative Glycemic Exposure.
Lee CG, Ciarleglio A, Edelstein SL, Crandall JP, Dabelea D, Goldberg RB, Kahn SE, Knowler WC, Ma MT, White NH, Herman WH; Diabetes Prevention Program Research Group. Lee CG, et al. Diabetes Care. 2024 May 1;47(5):810-817. doi: 10.2337/dc23-2009. Diabetes Care. 2024. PMID: 38502874 Clinical Trial.
CONCLUSIONS: The likelihood of DSPN was similar across DPP treatment groups but higher for those with diabetes, longer diabetes duration, and higher cumulative glycemic exposure. ILS may have long-term benefits on DSPN for older adults....
CONCLUSIONS: The likelihood of DSPN was similar across DPP treatment groups but higher for those with diabetes, longer diabetes duration, an …
Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort.
Wong K, Pitcher D, Braddon F, Downward L, Steenkamp R, Annear N, Barratt J, Bingham C, Chrysochou C, Coward RJ, Game D, Griffin S, Hall M, Johnson S, Kanigicherla D, Karet Frankl F, Kavanagh D, Kerecuk L, Maher ER, Moochhala S, Pinney J, Sayer JA, Simms R, Sinha S, Srivastava S, Tam FWK, Turner AN, Walsh SB, Waters A, Wilson P, Wong E, Taylor CM, Nitsch D, Saleem M, Bockenhauer D, Bramham K, Gale DP; RaDaR consortium. Wong K, et al. Lancet. 2024 Mar 30;403(10433):1279-1289. doi: 10.1016/S0140-6736(23)02843-X. Epub 2024 Mar 13. Lancet. 2024. PMID: 38492578 Free article.
Addressing unmet therapeutic need for patients with rare kidney diseases could have a large beneficial effect on long-term kidney replacement therapy demand. FUNDING: RaDaR is funded by the Medical Research Council, Kidney Research UK, Kidney Care UK, and the Polycystic Ki …
Addressing unmet therapeutic need for patients with rare kidney diseases could have a large beneficial effect on long-term kidney rep …
FAST functional connectivity implicates P300 connectivity in working memory deficits in Alzheimer's disease.
Roy O, Moshfeghi Y, Ibanez A, Lopera F, Parra MA, Smith KM. Roy O, et al. Among authors: smith km. ArXiv [Preprint]. 2024 Feb 28:arXiv:2402.18489v1. ArXiv. 2024. PMID: 38463502 Free PMC article. Preprint.
We propose a novel methodology to overcome these problems called Filter Average Short-Term (FAST) functional connectivity. First, long-term, stable, functional connectivity is averaged across an entire study cohort for a given pair of Visual Short Term Memory …
We propose a novel methodology to overcome these problems called Filter Average Short-Term (FAST) functional connectivity. First, lon …
Pneumococcal Vaccination Strategies in 50-Year-Olds to Decrease Racial Disparities: A US Societal Perspective Cost-Effectiveness Analysis.
Altawalbeh SM, Wateska AR, Nowalk MP, Lin CJ, Harrison LH, Schaffner W, Zimmerman RK, Smith KJ. Altawalbeh SM, et al. Among authors: smith kj. Value Health. 2024 Mar 8:S1098-3015(24)00094-9. doi: 10.1016/j.jval.2024.02.021. Online ahead of print. Value Health. 2024. PMID: 38462225
Pneumococcal disease societal costs were estimated using direct and indirect costs of acute illness and of pneumococcal-related long-term disability and mortality. Hypothetical 50-year-old cohorts were followed over their lifetimes with costs and effectiveness discounted 3 …
Pneumococcal disease societal costs were estimated using direct and indirect costs of acute illness and of pneumococcal-related long-term …
Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19.
Hanson AL, Mulè MP, Ruffieux H, Mescia F, Bergamaschi L, Pelly VS, Turner L, Kotagiri P; Cambridge Institute of Therapeutic Immunology and Infectious Disease–National Institute for Health Research (CITIID–NIHR) COVID BioResource Collaboration; Göttgens B, Hess C, Gleadall N, Bradley JR, Nathan JA, Lyons PA, Drakesmith H, Smith KGC. Hanson AL, et al. Among authors: smith kgc. Nat Immunol. 2024 Mar;25(3):471-482. doi: 10.1038/s41590-024-01754-8. Epub 2024 Mar 1. Nat Immunol. 2024. PMID: 38429458 Free PMC article.
776 results