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Determinants of lung function development from birth to age 5 years: an interrupted time series analysis of a South African birth cohort.
McCready C, Zar HJ, Chaya S, Jacobs C, Workman L, Hantos Z, Hall GL, Sly PD, Nicol MP, Stein DJ, Ullah A, Custovic A, Little F, Gray DM. McCready C, et al. Among authors: sly pd. Lancet Child Adolesc Health. 2024 Apr 12:S2352-4642(24)00072-5. doi: 10.1016/S2352-4642(24)00072-5. Online ahead of print. Lancet Child Adolesc Health. 2024. PMID: 38621408 Free article.
BACKGROUND: Early life is a key period that determines long-term health. Lung development in childhood predicts lung function attained in adulthood and morbidity and mortality across the life course. We aimed to assess the effect of early-life lower respiratory tract infec …
BACKGROUND: Early life is a key period that determines long-term health. Lung development in childhood predicts lung function attaine …
Bronchiolitis hospital admission in infancy is associated with later preschool ventilation inhomogeneity.
Sena CRDS, Morten M, Collison AM, Shaar A, Andrade EQ, Meredith J, Kepreotes E, Murphy VE, Sly PD, Whitehead B, Karmaus W, Gibson PG, Robinson PD, Mattes J. Sena CRDS, et al. Among authors: sly pd. Pediatr Pulmonol. 2024 Mar;59(3):632-641. doi: 10.1002/ppul.26793. Epub 2023 Dec 13. Pediatr Pulmonol. 2024. PMID: 38088225
Differences between groups were calculated using logistic and linear regression and adjusted for confounders (sex, age at bronchiolitis admission, height at visit, maternal asthma, and doctor-diagnosed asthma, including interaction terms between the latter three). An interaction …
Differences between groups were calculated using logistic and linear regression and adjusted for confounders (sex, age at bronchiolitis admi …
Trajectories of psychosocial environmental factors and their associations with asthma symptom trajectories among children in Australia.
Shahunja KM, Sly PD, Mamun A. Shahunja KM, et al. Among authors: sly pd. Pediatr Pulmonol. 2024 Jan;59(1):151-162. doi: 10.1002/ppul.26733. Epub 2023 Oct 26. Pediatr Pulmonol. 2024. PMID: 37882548
Associations between psychosocial factors and three distinct asthma symptom trajectories were assessed by multivariable logistic regression. RESULTS: We included 3917 children from the LSAC birth cohort in our study. We identified distinct trajectories for maternal depress …
Associations between psychosocial factors and three distinct asthma symptom trajectories were assessed by multivariable logistic regression. …
Peripheral airway dysfunction in prematurity-associated obstructive lung disease identified by oscillometry.
Cousins M, Hart K, Radics BL, Henderson AJ, Hantos Z, Sly PD, Kotecha S. Cousins M, et al. Among authors: sly pd. Pediatr Pulmonol. 2023 Nov;58(11):3279-3292. doi: 10.1002/ppul.26658. Epub 2023 Sep 13. Pediatr Pulmonol. 2023. PMID: 37701982 Free PMC article.
INTRODUCTION: Mechanisms underlying lung dysfunction after preterm birth are poorly understood. Studying phenotypes of prematurity-associated lung disease may aid understanding of underlying mechanisms. Preterm-born children with and without lung dysfunction and term
INTRODUCTION: Mechanisms underlying lung dysfunction after preterm birth are poorly understood. Studying phenotypes of prematurity-as …
Wearing masks as a protective measure for children against traffic-related air pollution: A comparison of perceptions between school children and their caregivers in Ho Chi Minh City, Vietnam.
Le HHTC, Vien NT, Dang TN, Ware RS, Phung D, Thai PK, Ranganathan S, Vinh NN, Dung PHT, Thanh HN, Dung TTT, Hien TT, Sly PD, Le An P. Le HHTC, et al. Among authors: sly pd. Trop Med Int Health. 2023 Sep;28(9):753-762. doi: 10.1111/tmi.13923. Epub 2023 Aug 24. Trop Med Int Health. 2023. PMID: 37615211 Free PMC article.
BACKGROUND: Traffic-related air pollution (TRAP) problems are unlikely to be solved in the short term, making it imperative to educate children on protective measures to mitigate the negative impact on their health. ...
BACKGROUND: Traffic-related air pollution (TRAP) problems are unlikely to be solved in the short term, making it imperative to educat …
Environmental Impacts on Infectious Disease: A Literature View of Epidemiological Evidence.
Sly PD, Trottier B, Ikeda-Araki A, Vilcins D. Sly PD, et al. Ann Glob Health. 2022 Oct 21;88(1):91. doi: 10.5334/aogh.3670. eCollection 2022. Ann Glob Health. 2022. PMID: 36348708 Free PMC article. Review.
FINDINGS AND CONCLUSIONS: The Hokkaido longitudinal children's study has found that exposure to chemicals in early life, such as persistent organic pollutants and per/polyfluorinated compounds, is associated with a range of immunological outcomes such as decreased cord blood IgE, …
FINDINGS AND CONCLUSIONS: The Hokkaido longitudinal children's study has found that exposure to chemicals in early life, such as persistent …
Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood.
Foong RE, Franklin P, Sanna F, Hall GL, Sly PD, Thorstensen EB, Doherty DA, Keelan JA, Hart RJ. Foong RE, et al. Among authors: sly pd. Respirology. 2023 Mar;28(3):236-246. doi: 10.1111/resp.14386. Epub 2022 Oct 2. Respirology. 2023. PMID: 36184579 Free PMC article.
BACKGROUND AND OBJECTIVE: Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may increase risk for asthma and allergies. However, little is known about the long-term effects of early life exposure to these compounds. W …
BACKGROUND AND OBJECTIVE: Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may incr …
Asthma and allergies in a cohort of adolescents conceived with ART.
Wijs LA, Doherty DA, Keelan JA, Penova-Veselinovic B, Burton P, Yovich JL, Hall GL, Sly PD, Holt PG, Hart RJ. Wijs LA, et al. Among authors: sly pd. Reprod Biomed Online. 2022 Dec;45(6):1255-1265. doi: 10.1016/j.rbmo.2022.07.007. Epub 2022 Jul 16. Reprod Biomed Online. 2022. PMID: 36182641
DESIGN: The Growing Up Healthy Study (GUHS) is a prospective cohort study including ART-conceived offspring born between 1991 and 2001 in Perth, Australia. Their long-term health outcomes, including asthma and allergy parameters, were compared with those of their counterpa …
DESIGN: The Growing Up Healthy Study (GUHS) is a prospective cohort study including ART-conceived offspring born between 1991 and 2001 in Pe …
Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort study.
Sanna F, Locatelli F, Sly PD, White E, Blake D, Heyworth J, Hall GL, Foong RE. Sanna F, et al. Among authors: sly pd. ERJ Open Res. 2022 Mar 21;8(1):00072-2022. doi: 10.1183/23120541.00072-2022. eCollection 2022 Jan. ERJ Open Res. 2022. PMID: 35350282 Free PMC article.
The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments. METHODS: Our study included participants from the Raine Study, a prospective pregnancy cohort, with at least two spirometry me …
The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung …
Exacerbation of chronic cigarette-smoke induced lung disease by rhinovirus in mice.
Larcombe AN, Iosifidis T, Foong RE, Berry LJ, Stumbles PA, Strickland DH, Sly PD, Kicic A. Larcombe AN, et al. Among authors: sly pd. Respir Physiol Neurobiol. 2022 Apr;298:103846. doi: 10.1016/j.resp.2022.103846. Epub 2022 Jan 19. Respir Physiol Neurobiol. 2022. PMID: 35063696
A significant proportion of chronic obstructive pulmonary disease exacerbations are strongly associated with rhinovirus infection (HRV). In this study, we combined long-term cigarette smoke exposure with HRV infection in a mouse model. ...Cigarette smoke and HRV-1A togethe …
A significant proportion of chronic obstructive pulmonary disease exacerbations are strongly associated with rhinovirus infection (HRV). In …
63 results