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Early Enzymatic Burn Debridement: Results of the DETECT Multicenter Randomized Controlled Trial.
Shoham Y, Rosenberg L, Hickerson W, Goverman J, Iyer N, Barrera-Oro J, Lipovy B, Monstrey S, Blome-Eberwein S, Wibbenmeyer LA, Scharpenberg M, Singer AJ. Shoham Y, et al. Among authors: singer aj. J Burn Care Res. 2024 Mar 4;45(2):297-307. doi: 10.1093/jbcr/irad142. J Burn Care Res. 2024. PMID: 37715999 Clinical Trial.
We tested the hypothesis that enzymatic debridement with NexoBrid would remove the eschar reducing surgery and achieve comparable long-term outcomes as standard of care (SOC). In this Phase 3 trial, we randomly assigned adults with deep burns (covering 3-30% of total body …
We tested the hypothesis that enzymatic debridement with NexoBrid would remove the eschar reducing surgery and achieve comparable long-te …
Closing the gap in osteoporosis management: the critical role of primary care in bone health.
Singer AJ, Sharma A, Deignan C, Borgermans L. Singer AJ, et al. Curr Med Res Opin. 2023 Mar;39(3):387-398. doi: 10.1080/03007995.2022.2141483. Epub 2023 Jan 24. Curr Med Res Opin. 2023. PMID: 36597741 Review.
RESULTS: We present a systematic approach to facilitate osteoporosis assessment and management that includes four steps: (1) identifying patients at risk through proactive screening strategies, (2) investigating and diagnosing patients, (3) intervening with personalized treatment …
RESULTS: We present a systematic approach to facilitate osteoporosis assessment and management that includes four steps: (1) identifying pat …
Defining Acute Traumatic Encephalopathy: Methods of the "HEAD Injury Serum Markers and Multi-Modalities for Assessing Response to Trauma" (HeadSMART II) Study.
Peacock WF, Kuehl D, Bazarian J, Singer AJ, Cannon C, Rafique Z, d'Etienne JP, Welch R, Clark C, Diaz-Arrastia R. Peacock WF, et al. Among authors: singer aj. Front Neurol. 2021 Dec 8;12:733712. doi: 10.3389/fneur.2021.733712. eCollection 2021. Front Neurol. 2021. PMID: 34956041 Free PMC article.
The recognition that "mild" forms of TBI and even sub-clinical impacts can result in persistent neuropsychiatric consequences, particularly when repetitive, highlights the need for objective assessments that can complement the clinical diagnosis and provide prognostic information …
The recognition that "mild" forms of TBI and even sub-clinical impacts can result in persistent neuropsychiatric consequences, particularly …
Treatment patterns and long-term persistence with osteoporosis therapies in women with Medicare fee-for-service (FFS) coverage.
Singer AJ, Liu J, Yan H, Stad RK, Gandra SR, Yehoshua A. Singer AJ, et al. Osteoporos Int. 2021 Dec;32(12):2473-2484. doi: 10.1007/s00198-021-05951-1. Epub 2021 Jun 7. Osteoporos Int. 2021. PMID: 34095966 Free PMC article.
Longer-term persistence was higher among women who persisted in the first year of therapy. INTRODUCTION: Osteoporosis, a chronic, progressive disease, requires long-term therapy; this study assessed long-term persistence with anti-resorptive therapies in post …
Longer-term persistence was higher among women who persisted in the first year of therapy. INTRODUCTION: Osteoporosis, a chronic, pro …
Reducing the hospital burden associated with the treatment of pulmonary embolism.
Peacock WF, Singer AJ. Peacock WF, et al. Among authors: singer aj. J Thromb Haemost. 2019 May;17(5):720-736. doi: 10.1111/jth.14423. Epub 2019 Apr 1. J Thromb Haemost. 2019. PMID: 30851227 Free PMC article. Review.
The available data on outpatient treatment of PE are summarized, including details on patient selection, anticoagulant choice, and short-term outcomes in each study. Accumulating evidence suggests that outcomes in patients with low-risk PE treated as outpatients are at lea …
The available data on outpatient treatment of PE are summarized, including details on patient selection, anticoagulant choice, and short- …
Minimally invasive burn care: a review of seven clinical studies of rapid and selective debridement using a bromelain-based debriding enzyme (Nexobrid®).
Rosenberg L, Shoham Y, Krieger Y, Rubin G, Sander F, Koller J, David K, Egosi D, Ahuja R, Singer AJ. Rosenberg L, et al. Among authors: singer aj. Ann Burns Fire Disasters. 2015 Dec 31;28(4):264-274. Ann Burns Fire Disasters. 2015. PMID: 27777547 Free PMC article.
The incidence of surgical debridement in patients treated with DGD was lower than the SOC (40/163 [24.5%] vs. 119/170 [70.0%], P0.001). Less autografting was used in all studies. Long-term scar quality and function were similar in DGD- and SOCtreated. ...
The incidence of surgical debridement in patients treated with DGD was lower than the SOC (40/163 [24.5%] vs. 119/170 [70.0%], P0.001). Less …
The Long-Term Effect of an Independent Capacity Protocol on Emergency Department Length of Stay: A before and after Study.
Cha WC, Song KJ, Cho JS, Singer AJ, Shin SD. Cha WC, et al. Among authors: singer aj. Yonsei Med J. 2015 Sep;56(5):1428-36. doi: 10.3349/ymj.2015.56.5.1428. Yonsei Med J. 2015. PMID: 26256991 Free PMC article.
PURPOSE: In this study, we determined the long-term effects of the Independent Capacity Protocol (ICP), in which the emergency department (ED) is temporarily used to stabilize patients, followed by transfer of patients to other facilities when necessary, on crowding metric …
PURPOSE: In this study, we determined the long-term effects of the Independent Capacity Protocol (ICP), in which the emergency depart …
ICG angiography predicts burn scarring within 48 h of injury in a porcine vertical progression burn model.
Fourman MS, McKenna P, Phillips BT, Crawford L, Romanelli F, Lin F, McClain SA, Khan SU, Dagum AB, Singer AJ, Clark RA. Fourman MS, et al. Among authors: singer aj. Burns. 2015 Aug;41(5):1043-8. doi: 10.1016/j.burns.2014.11.001. Epub 2014 Dec 11. Burns. 2015. PMID: 25499407
Findings suggest that ICG angiography may have significant potential in the prediction of long-term burn outcomes....
Findings suggest that ICG angiography may have significant potential in the prediction of long-term burn outcomes....
Health economic aspects of vertebral augmentation procedures.
Borgström F, Beall DP, Berven S, Boonen S, Christie S, Kallmes DF, Kanis JA, Olafsson G, Singer AJ, Åkesson K. Borgström F, et al. Among authors: singer aj. Osteoporos Int. 2015 Apr;26(4):1239-49. doi: 10.1007/s00198-014-2953-5. Epub 2014 Nov 8. Osteoporos Int. 2015. PMID: 25381046 Review.
Rather, studies that can reduce the uncertainty in the underlying data, especially regarding the long-term clinical outcomes of VAPs, should be conducted....
Rather, studies that can reduce the uncertainty in the underlying data, especially regarding the long-term clinical outcomes of VAPs, …
24 results