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Reirradiation With Proton Therapy for Recurrent Malignancies of the Esophagus and Gastroesophageal Junction: Results of the Proton Collaborative Group Multi-Institutional Prospective Registry Trial.
Hotca A, Sindhu KK, Lehrer EJ, Hartsell WF, Vargas C, Tsai HK, Chang JH, Apisarnthanarax S, Nichols RC Jr, Chhabra AM, Hasan S, Press RH, Lazarev S, Hajj C, Kabarriti R, Rule WG, Simone CB 2nd, Choi JI. Hotca A, et al. Among authors: simone cb 2nd. Adv Radiat Oncol. 2024 Feb 6;9(5):101459. doi: 10.1016/j.adro.2024.101459. eCollection 2024 May. Adv Radiat Oncol. 2024. PMID: 38596455 Free PMC article.
However, these findings are limited by the poor prognoses of these patients, who are at high risk of mortality. Further research is needed to better assess the long-term benefits and toxicities of PBT in this specific patient population....
However, these findings are limited by the poor prognoses of these patients, who are at high risk of mortality. Further research is needed t …
Bimekizumab for the Treatment of Plaque Psoriasis With Involvement of Genitalia: A 16-Week Multicenter Real-World Experience - IL PSO (Italian Landscape Psoriasis).
Orsini D, Malagoli P, Balato A, Bianchi L, Brianti P, Buononato D, Burlando M, Caldarola G, Campanati A, Campione E, Carrera CG, Carugno A, Cusano F, Dapavo P, Dattola A, De Simone C, Dini V, Esposito M, Fargnoli MC, Gaiani FM, Gargiulo L, Gisondi P, Giunta A, Ibba L, Lasagni C, Loconsole F, Maione V, Mortato E, Marzano AV, Maurelli M, Megna M, Mercuri SR, Narcisi A, Offidani A, Paolino G, Parodi A, Pellacani G, Potestio L, Quaglino P, Richetta AG, Romano F, Sena P, Venturini M, Assorgi C, Costanzo A. Orsini D, et al. Among authors: de simone c. Dermatol Pract Concept. 2024 Apr 1. doi: 10.5826/dpc.1402a52. Online ahead of print. Dermatol Pract Concept. 2024. PMID: 38416060 Free article.
Nevertheless, further research with larger sample sizes and longer-term follow-up is imperative to conclusively validate these results....
Nevertheless, further research with larger sample sizes and longer-term follow-up is imperative to conclusively validate these result …
Classic Galactosemia: Clinical and Computational Characterization of a Novel GALT Missense Variant (p.A303D) and a Literature Review.
Forte G, Buonadonna AL, Pantaleo A, Fasano C, Capodiferro D, Grossi V, Sanese P, Cariola F, De Marco K, Lepore Signorile M, Manghisi A, Guglielmi AF, Simonetti S, Laforgia N, Disciglio V, Simone C. Forte G, et al. Among authors: simone c. Int J Mol Sci. 2023 Dec 12;24(24):17388. doi: 10.3390/ijms242417388. Int J Mol Sci. 2023. PMID: 38139222 Free PMC article. Review.
While a galactose-restricted diet is lifesaving, most patients still develop long-term complications. In this study, we report on a two-week-old female patient who is a compound heterozygote for a known pathogenic variant (p.K285N) and a novel missense variant (p.A303D) in …
While a galactose-restricted diet is lifesaving, most patients still develop long-term complications. In this study, we report on a t …
Latest clinical research in leptomeningeal disease (LMD)-a narrative review.
Chan AW, Wong HCY, Taphoorn M, Dirven L, Le Rhun E, Soliman H, Oldenburger E, Raman S, Vassiliou V, Bonomo P, Koller M, Marta GN, Rembielak A, Lee SF, Chow E, Simone CB 2nd. Chan AW, et al. Among authors: simone cb 2nd. Ann Palliat Med. 2023 Nov;12(6):1215-1231. doi: 10.21037/apm-23-390. Epub 2023 Oct 27. Ann Palliat Med. 2023. PMID: 37953219 Free article. Review.
METHODS: A narrative review of clinical trials in LMD was conducted based on a search in clinicatrials.gov using the search term "leptomeningeal" under "condition or disease". Clinical trials in patients with LMD arising from solid malignancy that were labelled as "not yet …
METHODS: A narrative review of clinical trials in LMD was conducted based on a search in clinicatrials.gov using the search term "lep …
Topical Treatment for the Management of Mild-to-Moderate Psoriasis: A Critical Appraisal of the Current Literature.
Fargnoli MC, De Simone C, Gisondi P, Pellacani G, Calzavara-Pinton P. Fargnoli MC, et al. Among authors: de simone c. Dermatol Ther (Heidelb). 2023 Nov;13(11):2527-2547. doi: 10.1007/s13555-023-01024-9. Epub 2023 Sep 22. Dermatol Ther (Heidelb). 2023. PMID: 37737941 Free PMC article. Review.
This study critically appraises the available literature on all topical treatments of psoriasis from the past 20 years to address some relevant issues, such as the vehicle associated with the highest effectiveness, the best vehicle for improving patient adherence, and the best st …
This study critically appraises the available literature on all topical treatments of psoriasis from the past 20 years to address some relev …
The preclinical discovery and development of deucravacitinib for the treatment of psoriasis.
Coscarella G, Malvaso D, Mannino M, Caldarola G, Fossati B, De Simone C, Chiricozzi A, Peris K. Coscarella G, et al. Among authors: de simone c. Expert Opin Drug Discov. 2023 Jul-Dec;18(11):1201-1208. doi: 10.1080/17460441.2023.2246880. Epub 2023 Aug 13. Expert Opin Drug Discov. 2023. PMID: 37574849 Review.
Because of its oral administration, deucravacitinib represents an intriguing option in the therapeutic armamentarium of psoriasis, though the evaluation of long-term efficacy and safety is necessary to establish its place-in-therapy....
Because of its oral administration, deucravacitinib represents an intriguing option in the therapeutic armamentarium of psoriasis, though th …
Drug survival of methotrexate and predictor factors for discontinuation in psoriasis.
Caldarola G, De Luca E, Mariani M, Chiricozzi A, Peris K, De Simone C. Caldarola G, et al. Among authors: de simone c. Int J Dermatol. 2023 May;62(5):649-656. doi: 10.1111/ijd.16652. Epub 2023 Mar 24. Int J Dermatol. 2023. PMID: 36961109
There is a lack of data on its use in daily practice and particularly on its long-term effectiveness and survival in psoriasis. METHODS: We performed a single-centered, retrospective, observational study to evaluate the drug survival of MTX in patients with psoriasis, trea …
There is a lack of data on its use in daily practice and particularly on its long-term effectiveness and survival in psoriasis. METHO …
Real-life experience with ixekizumab in plaque psoriasis: a multi-center, retrospective, 3-year study.
Caldarola G, Chiricozzi A, Megna M, Dapavo P, Giunta A, Burlando M, Malagoli P, Dini V, Mariani M, Fabbrocini G, Quaglino P, Bianchi L, Parodi A, Peris K, De Simone C. Caldarola G, et al. Among authors: de simone c. Expert Opin Biol Ther. 2023 Apr;23(4):365-370. doi: 10.1080/14712598.2023.2193288. Epub 2023 Mar 20. Expert Opin Biol Ther. 2023. PMID: 36927246
BACKGROUND: Confirmatory data on the long-term effectiveness and safety of ixekizumab in psoriatic patients from real-world studies are needed. ...CONCLUSIONS: We found that ixekizumab is a biological agent characterized by long-term effectiveness, not influenced by …
BACKGROUND: Confirmatory data on the long-term effectiveness and safety of ixekizumab in psoriatic patients from real-world studies a …
Policies and Processes for Accessibility from a UD Perspective: The Integrated Approach Supported by the Friuli Venezia Giulia Region (IT).
Burelli A, Simone C. Burelli A, et al. Among authors: simone c. Stud Health Technol Inform. 2022 Sep 2;297:247-254. doi: 10.3233/SHTI220846. Stud Health Technol Inform. 2022. PMID: 36073401
With Regional Law no. 10 of 19 March 2018 (General principles and implementing provisions on accessibility), the Autonomous Region of Friuli Venezia Giulia has set itself the objective of improving urban accessibility throughout the regional territory, in order to guarantee equal …
With Regional Law no. 10 of 19 March 2018 (General principles and implementing provisions on accessibility), the Autonomous Region of Friuli …
Long-term proactive management of psoriasis with calcipotriol and betamethasone dipropionate foam: an Italian consensus through a combined nominal group technique and Delphi approach.
De Simone C, Dapavo P, Malagoli P, Martella A, Campanati A, Campione E, Errichetti E, Franchi C, Gambardella A, Megna M, Osti F, Ribero S, Zagni G, Calzavara-Pinton P, Fabbrocini G; PAM Italian Working Group; Amoruso GF, Baglieri F, Biamonte AS, Bianchelli T, Bigi L, Bortoli J, Brunetti B, Buligan C, Cagni E, Calderoni O, Calzavara-Pinton P, Campanati A, Caputo A, Carrera CG, Carugno A, Chersi K, Cicchelli S, De Natale F, De Simone C, Dapavo P, Di Maria D, Errichetti E, Fabbrocini G, Ferrari AS, Fogli E, Forconi R, Franchi C, Galeazzi A, Gambardella A, Giovannini A, Giura MT, Iuculano M, Lazzaretti G, Leporati C, Magnanini M, Malagoli P, Marconi B, Martella A, Maruccia A, Megna M, Miglietta R, Minuti A, Mocci L, Modica S, Narcisi A, Odorici G, Osti F, Pazzaglia M, Peila R, Pertusi G, Pezza M, Pezzullo E, Puccia N, Raulo U, Ribero S, Rossi M, Rusignuolo S, Sapienza G, Savarese C, Scalisi M, Strippoli D, Stroppiana E, Tiberio R, Trischitta A, Tucci MG, Vaira F, Verrone A, Villa L, Zagni F, Zoccali A. De Simone C, et al. Int J Dermatol. 2022 Dec;61(12):1543-1551. doi: 10.1111/ijd.16192. Epub 2022 May 24. Int J Dermatol. 2022. PMID: 35609147 Free PMC article.
BACKGROUND: Although long-term management of psoriasis is paramount, this approach is challenging in clinical practice. ...RESULTS: Eighteen statements were proposed, and the majority of them (14/18) reached a consensus during the Delphi voting. The need to provide long- …
BACKGROUND: Although long-term management of psoriasis is paramount, this approach is challenging in clinical practice. ...RESULTS: E …
67 results