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Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A.
Yu D, Thakor DK, Han I, Ropper AE, Haragopal H, Sidman RL, Zafonte R, Schachter SC, Teng YD. Yu D, et al. Among authors: sidman rl. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E746-55. doi: 10.1073/pnas.1300083110. Epub 2013 Feb 5. Proc Natl Acad Sci U S A. 2013. PMID: 23386718 Free PMC article.
Because conventional treatments blocking individual mechanisms elicit only short-term effectiveness, a multimodal approach with simultaneous actions against major pain-related pathways may have value for clinical management of chronic pain. ...
Because conventional treatments blocking individual mechanisms elicit only short-term effectiveness, a multimodal approach with simul …
Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice.
Reimold AM, Grusby MJ, Kosaras B, Fries JW, Mori R, Maniwa S, Clauss IM, Collins T, Sidman RL, Glimcher MJ, Glimcher LH. Reimold AM, et al. Among authors: sidman rl. Nature. 1996 Jan 18;379(6562):262-5. doi: 10.1038/379262a0. Nature. 1996. PMID: 8538792
Unlike CREB alpha/delta-deficient mice whose main defect is in long-term potentiation, the widespread abnormalities in ATF-2 mutant mice demonstrate its absolute requirement for skeletal and central nervous system development, and for maximal induction of select genes with …
Unlike CREB alpha/delta-deficient mice whose main defect is in long-term potentiation, the widespread abnormalities in ATF-2 mutant m …
A genetic variant in the morphology of the medial preoptic area in mice.
Robinson SM, Fox TO, Sidman RL. Robinson SM, et al. Among authors: sidman rl. J Neurogenet. 1985 Dec;2(6):381-8. doi: 10.3109/01677068509101424. J Neurogenet. 1985. PMID: 4078650
We describe a distinguishing nucleus of darkly staining, densely packed cells, which we term the medioventral pars compacta (MVPC), within the medial preoptic nucleus of DBA/2J, but not C57BL/6J mice. ...
We describe a distinguishing nucleus of darkly staining, densely packed cells, which we term the medioventral pars compacta (MVPC), w …
Cross-linked collagen surface for cell culture that is stable, uniform, and optically superior to conventional surfaces.
Macklis JD, Sidman RL, Shine HD. Macklis JD, et al. Among authors: sidman rl. In Vitro Cell Dev Biol. 1985 Mar;21(3 Pt 1):189-94. doi: 10.1007/BF02621357. In Vitro Cell Dev Biol. 1985. PMID: 3859483
Collagen is derivatized to plastic culture dishes by a cross-linking reagent, l-cyclohexyl-3-(2-morpholinoethyl)-carbodiimide-metho-p-toluene sulfonate (carbodiimide), to form a uniform and durable surface for cell attachment and growth that allows dry storage, long-term c …
Collagen is derivatized to plastic culture dishes by a cross-linking reagent, l-cyclohexyl-3-(2-morpholinoethyl)-carbodiimide-metho-p-toluen …
The multiple molecular forms of acetylcholinesterase in "motor end-plate disease" in the mouse (medJ and med allelic forms): sensitivity of the 10 S form to partial or total loss of muscle activity.
Rieger F, Shelanski ML, Sidman RL. Rieger F, et al. Among authors: sidman rl. Exp Neurol. 1983 Feb;79(2):299-315. doi: 10.1016/0014-4886(83)90215-7. Exp Neurol. 1983. PMID: 6822265
A decrease in the 10 S AChE proportion to total AChE activity is the major change in gastrocnemius muscle. Similar AChE changes occur after total short-term denervation, tenotomy, and in other genetic diseases. Thus it appears that AChE is modified in med/med muscle as the …
A decrease in the 10 S AChE proportion to total AChE activity is the major change in gastrocnemius muscle. Similar AChE changes occur after …
Neurochemical and morphological consequences of axon terminal degeneration in cerebellar deep nuclei of mice with inherited Purkinje cell degeneration.
Roffler-Tarlov S, Beart PM, O'Gorman S, Sidman RL. Roffler-Tarlov S, et al. Among authors: sidman rl. Brain Res. 1979 May 18;168(1):75-95. doi: 10.1016/0006-8993(79)90129-x. Brain Res. 1979. PMID: 455087
No other measured free amino acid decreased. There were no long-term increases following Purkinje cell degeneration in the concentration of any transmitter amino acids or related enzymes, GAD, ChAC or GABA-t, and thus no indication of axonal sprouting reactions. ...
No other measured free amino acid decreased. There were no long-term increases following Purkinje cell degeneration in the concentrat …