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Epidemiology of SARS-CoV-2 infection among staff and students in a cohort of English primary and secondary schools during 2020-2021.
Hargreaves JR, Langan SM, Oswald WE, Halliday KE, Sturgess J, Phelan J, Nguipdop-Djomo P, Ford B, Allen E, Sundaram N, Ireland G, Poh J, Ijaz S, Diamond I, Rourke E, Dawe F, Judd A, Warren-Gash C, Clark TG, Glynn JR, Edmunds WJ, Bonell C, Mangtani P, Ladhani SN; COVID-19 Schools Infection Survey Study Group. Hargreaves JR, et al. Lancet Reg Health Eur. 2022 Oct;21:100471. doi: 10.1016/j.lanepe.2022.100471. Epub 2022 Aug 24. Lancet Reg Health Eur. 2022. PMID: 36035630 Free PMC article.
SARS-CoV-2 infection prevalence among those attending school was highest during the first two rounds of testing in the autumn term, ranging from 0.7% (95% CI 0.2, 1.2) among primary staff in November 2020 to 1.6% (95% CI 0.9, 2.3) among secondary staff in December 2020. An …
SARS-CoV-2 infection prevalence among those attending school was highest during the first two rounds of testing in the autumn term, r …
Longitudinal Follow-up of Impedance Drift in Deep Brain Stimulation Cases.
Wong J, Gunduz A, Shute J, Eisinger R, Cernera S, Ho KWD, Martinez-Ramirez D, Almeida L, Wilson CA, Okun MS, Hess CW. Wong J, et al. Among authors: shute j. Tremor Other Hyperkinet Mov (N Y). 2018 Mar 26;8:542. doi: 10.7916/D8M62XTC. eCollection 2018. Tremor Other Hyperkinet Mov (N Y). 2018. PMID: 29607241 Free PMC article.
BACKGROUND: Impedance is an integral property of neuromodulation devices that determines the current delivered to brain tissue. Long-term variability in therapeutic impedance following deep brain stimulation (DBS) has not been extensively investigated across different brai …
BACKGROUND: Impedance is an integral property of neuromodulation devices that determines the current delivered to brain tissue. Long-term …
Human mid-gestation amniotic fluid contains interleukin-16 bioactivity.
Thornton CA, Holloway JA, Shute JK, Holloway JW, Diaper ND, Warner JO. Thornton CA, et al. Among authors: shute jk. Immunology. 2009 Apr;126(4):543-51. doi: 10.1111/j.1365-2567.2008.02903.x. Immunology. 2009. PMID: 19278422 Free PMC article.
We have shown that IL-16 was detectable in human amniotic fluid at 16-18 weeks of gestation (mid-pregnancy) but was not detectable at term (late pregnancy; > 37 weeks of gestation). Similarly, mid-pregnancy, but not late pregnancy, amniotic fluid contained chemotactic a …
We have shown that IL-16 was detectable in human amniotic fluid at 16-18 weeks of gestation (mid-pregnancy) but was not detectable at ter …
Inflammatory responses to the occupational inhalation of metal fume.
Palmer KT, McNeill Love RM, Poole JR, Coggon D, Frew AJ, Linaker CH, Shute JK. Palmer KT, et al. Among authors: shute jk. Eur Respir J. 2006 Feb;27(2):366-73. doi: 10.1183/09031936.06.00053205. Eur Respir J. 2006. PMID: 16452594 Free article.
Induced sputum and venous blood samples were collected from 27 welders with regular long-term exposure to ferrous metal fume and 31 unexposed matched controls. ...
Induced sputum and venous blood samples were collected from 27 welders with regular long-term exposure to ferrous metal fume and 31 u …
Inhaled heparin in cystic fibrosis.
Serisier DJ, Shute JK, Hockey PM, Higgins B, Conway J, Carroll MP. Serisier DJ, et al. Among authors: shute jk. Eur Respir J. 2006 Feb;27(2):354-8. doi: 10.1183/09031936.06.00069005. Eur Respir J. 2006. PMID: 16452592 Free article. Clinical Trial.
Unfractionated heparin may be mucolytic and has demonstrated a number of anti-inflammatory properties; however, further safety data are needed in these subjects who are at risk of airway bleeding. The current study aimed to assess the medium-term safety and tolerability of …
Unfractionated heparin may be mucolytic and has demonstrated a number of anti-inflammatory properties; however, further safety data are need …
Effect of treatment with dornase alpha on airway inflammation in patients with cystic fibrosis.
Paul K, Rietschel E, Ballmann M, Griese M, Worlitzsch D, Shute J, Chen C, Schink T, Döring G, van Koningsbruggen S, Wahn U, Ratjen F; Bronchoalveolar Lavage for the Evaluation of Antiinflammatory Treatment Study Group. Paul K, et al. Among authors: shute j. Am J Respir Crit Care Med. 2004 Mar 15;169(6):719-25. doi: 10.1164/rccm.200307-959OC. Epub 2003 Dec 18. Am J Respir Crit Care Med. 2004. PMID: 14684561 Clinical Trial.
Recombinant human deoxyribonuclease (rhDNase) has been shown to improve lung function and reduce the number of pulmonary exacerbations in patients with cystic fibrosis (CF), but its long-term effect on airway inflammation remains unknown. In this study, we used bronchoalve …
Recombinant human deoxyribonuclease (rhDNase) has been shown to improve lung function and reduce the number of pulmonary exacerbations in pa …
Fetal exposure to intact immunoglobulin E occurs via the gastrointestinal tract.
Thornton CA, Holloway JA, Popplewell EJ, Shute JK, Boughton J, Warner JO. Thornton CA, et al. Among authors: shute jk. Clin Exp Allergy. 2003 Mar;33(3):306-11. doi: 10.1046/j.1365-2222.2003.01614.x. Clin Exp Allergy. 2003. PMID: 12614443

Circulating IgE levels from women in Sao Paulo, Brazil, associated positively not only with term (> 37 weeks' gestation) amniotic fluid (rho = 0.993; P < 0.001) but also breast milk IgE levels (rho = 0.785; P = 0.001). ...The evolutionary significance of these intera

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Circulating IgE levels from women in Sao Paulo, Brazil, associated positively not only with term (> 37 weeks' gestation) amniotic …
Role of elevated plasma soluble ICAM-1 and bronchial lavage fluid IL-8 levels as markers of chronic lung disease in premature infants.
Little S, Dean T, Bevin S, Hall M, Ashton M, Church M, Warner J, Shute J. Little S, et al. Among authors: shute j. Thorax. 1995 Oct;50(10):1073-9. doi: 10.1136/thx.50.10.1073. Thorax. 1995. PMID: 7491556 Free PMC article.
The possibility that persistently raised markers of inflammation indicate the development of chronic lung disease in low birth weight (< 1730 g) preterm (< 31 weeks) infants was therefore investigated. ...Levels of IL-8 in BLF at 14 days of age correlated with the lo …
The possibility that persistently raised markers of inflammation indicate the development of chronic lung disease in low birth weight …